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Journal of the Korean Society for Therapeutic Radiology 1985;3(1): 9-12. |
| Radiosensitivity and Dose-urvival Characteristics of Crypt Cells of Mouse Jejunum |
| Seoung Jae Huh, Charn Il Park |
1Department of Radiology, College of Medicine, Soonchunhyang University, Korea.
2Department of Therapeutic Radiology, College of Medicine, Seoul University, Korea. |
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| ABSTRACT |
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To determine the radiosensitivity and dose-urvival characteristics of jejunal crypt cells, experimental study was done using total 40 mice. Single irradiation of 1,000rad to 1,600rad was delivered to whole bodies of mice, using a cesium 137 animal irradiator. The number of regenerating crypts per jejunal circumference was counted, by using a jejunal crypt cell assay technique, and dose response curve was measured. The average number of jejunal crypt per circumference in control group was 140+/-10. Mean lethal dose(D0) of mouse jejunal crypt cell was 135rad. |
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