Purpose: High-dose-rate (HDR) brachytherapy is a promising treatment modality for organ and function preservation in lip and oral cavity cancers. This study aims to describe the technique and assess clinical outcomes of HDR interstitial brachytherapy in patients diagnosed with lip and buccal mucosa cancer treated in a comprehensive cancer center. Materials and Methods: We conducted a retrospective analysis of six lip...

DOI: https://doi.org/10.3857/roj.2024.00682    [Epub ahead of print]

Purpose This study evaluated interfractional bladder volume variations and the resulting dosimetric changes during short-course radiotherapy (SCRT) 5X5Gy (RBE) in patients with locally advanced rectal cancer. Materials and methods Twenty patients received either protons or photons with daily cone-beam CT (CBCT). All patients received the same drinking instructions prior to the planning CT and each fraction. For each patient, VMAT and PBT plans...

DOI: https://doi.org/10.3857/roj.2024.00654    [Epub ahead of print]

Purpose: This study aimed to evaluate the effect of radiotherapy (RT) on symptomatic relief and tumor control in patients with breast cancer with skin involvement. Materials and Methods: This retrospective study included patients who received palliative RT of the breast or chest wall for breast cancer with skin involvement. Progression-free survival, freedom from local progression (FFLP), and symptomatic response were evaluated....

DOI: https://doi.org/10.3857/roj.2024.00122    [Epub ahead of print]

Purpose: Our purpose was to compare four whole brain radiotherapy (WBRT) delivery types: opposed lateral (OL) 3-dimensional-conformal radiotherapy (3D-CRT), a novel opposed lateral sparing (OLS) 3D-CRT technique, 3D optimized dynamic conformal arcs (optDCA), and hippocampal-avoidant WBRT (HA-WBRT). Materials and Methods: Ten patients previously undergoing HA-WBRT were retrospectively planned using OL, OLS, and optDCA techniques. OLS technique involved multi-leaf collimator (MLC) modifications...

DOI: https://doi.org/10.3857/roj.2023.01039    [Epub ahead of print]

Purpose: Stereotactic radiotherapy (SRT) is an important adjunctive treatment after excision of brain metastases. We investigated efficacy and safety outcomes of such treatment and the impact of radiotherapy dose fractionations in a real-world multi-center cohort. Materials and Methods: All patients who received resection cavity SRT between 2018–2022 were identified from institutional databases of two tertiary oncology centers. Patient and treatment characteristics...

DOI: https://doi.org/10.3857/roj.2024.00556    [Epub ahead of print]

This study evaluates the use of magnetic resonance–guided radiation therapy (MRgRT) as an alternative to brachytherapy in treating para-urethral gynecological cancers, particularly for patients who are not candidates for brachytherapy. Five female patients with advanced para-urethral gynecological cancers underwent MRgRT using a custom 3-dimensional-printed intravaginal cylinder for image registration and treatment alignment. MRgRT was administered as a five-fraction adaptive boost...

DOI: https://doi.org/10.3857/roj.2024.00584    [Epub ahead of print]

Radiation-induced cutaneous side effects are well known; however, the isoradiotopic phenomenon presenting as lichen planus is underreported in the literature. It is imperative to be aware of this entity to manage the patients accordingly. Herein, we report a 31-year-old male, a known case of carcinoma glottis who developed lichen planus confined to the radiation site and presented with a review...

DOI: https://doi.org/10.3857/roj.2024.00668    [Epub ahead of print]