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Table of Contents | , 2001  Vol. 19  No.4 Previous Issue | Next Issue | Archive
In this issue:



Review
Hypofractionated Radiation Therapy for Early Glottic Cancer: Preliminary Results
Hong Gyun Wu, Semie Hong, Seong Soo Shin, Charn Il Park
Radiat Oncol J. 2001;19(4):301-305.
PURPOSE: This study was performed for the evaluation of the feasibility and toxicity of hypofractionated radiation therapy for early glottic cancer METHODS AND MATERIALS: From February 1999 to February 2000, 20 patients with histologically confirmed Stage I, II glottic cancer were enrolled into this study. There were 18 males and 2 females, the median age of the patients was 59...
Case Report
Intramedullary Spinal Cord Metastasis: A Report of Two Cases and a Review of the Literature
Yoon Kyeong Oh, Hee Chul Park
Radiat Oncol J. 2001;19(4):353-358.
Intramedullary spinal cord metastases (ISCM) account for only 3.4% of symptomatic metastases to the spinal cord. The survival of patients with ISCM is characteristically short, often no longer than 2 months, due to a rapid neurologic deterioration and the presence of widespread metastases, including metastases to the brain. We report two cases of ISCM arising from primary sphenoid sinus carcinoma...
Original Articles
Prognostic Factors and Treatment Outcome for Thymoma
Hak Jae Kim, Charn Il Park, Seong Soo Shin, Joo Hyun Kim, Jeong Wook Seo
Radiat Oncol J. 2001;19(4):306-311.
PURPOSE: In this retrospective study, we attempted to evaluate the treatment outcome and the prognostic factors of thymoma treated with surgery, radiotherapy and chemotherapy. METHODS AND MATERIALS: Between 1979 and 1998, 55 patients with thymoma were treated at the Seoul National University Hospital. Of these, 11 patients underwent surgery only, 33 patients received postoperative radiotherapy and 11 patients received radiotherapy...
Postoperative Radiation Therapy in High-risk Breast Cancer
Kyung Ja Lee
Radiat Oncol J. 2001;19(4):312-318.
PURPOSE: To assess the locoregional recurrence rate, survival rate and prognostic factors after modified radical mastectomy and postoperative adjuvant radiation therapy with or with chemotherapy in high-risk breast cancer patients. METHODS: Between 1984-1995, 48 patients underwent postoperative irradiation to the regional lymphatics and chest wall due to large tumor size (> or = 5 cm) or small tumor size (<5 cm)...
Use of Respiratory Motion Reduction Device (RRD) in Treatment of Hepatoma
Suk Lee, Jinsil Seong, Yong Bae Kim, Kwang Hwan Cho, Joo Ho Kim, Sae Kyung Jang, Soo Il Kwon, Sung Sil Chu, Chang Ok Suh
Radiat Oncol J. 2001;19(4):319-326.
PURPOSE: Planning target volume (PTV) for tumors in abdomen or thorax includes enough margin for breathing-related movement of tumor volumes during treatment. Depending on the location of the tumor, the magnitude of PTV margin extends from 10 mm to 30 mm, which increases substantial volume of the irradiated normal tissue hence, resulting in increase of normal tissue complication probability (NTCP)....
Surgery Alone or Postoperative Adjuvant Radiotherapy in Rectal Cancer: With Respect to Survival, Pelvic Control, Prognostic Factor
Taek Keun Nam, Sung Ja Ahn, Byung Sik Nah
Radiat Oncol J. 2001;19(4):327-334.
PURPOSE: To find out the role of postoperative adjuvant radiotherapy in the treatment of rectal cancer by comparing survival, pelvic control, complication rate, and any prognostic factor between surgery alone and postoperative radiotherapy group. MATERIALS AND METHODS: From Feb. 1982 to Dec. 1996 total 212 patients were treated by radical surgery with or without postoperative radiotherapy due to rectal carcinoma of...
The Expression of Vascular Endothelial Growth Factor (VEGF) is a Highly Significant Prognostic Factor in Stage IB Carcinoma of the Cervix
Ik Jae Lee, Kyung Ran Park, Jong Young Lee, Kang Kyoo Lee, Ji Sun Song, Kwang Gil Lee, Dong Soo Cha, Hyun Il Choi
Radiat Oncol J. 2001;19(4):335-344.
PURPOSE: The aim of this study was to clarify the role of VEGF expression as an independent prognostic factor and to identify the patients at high risk for poor prognosis in stage IB cervical cancer. MATERIALS AND METHODS: A total of 118 patients with stage IB cervical cancer who had radical hysterectomy and pelvic lymph node dissection were included in the...
Radiotherapy Results in Stage IIB Uterine Cervix Cancer
Whoon Jong Kil, Mison Chun, Seunghee Kang, Young Taek Oh, Hee Sug Ryu, Hee Jae Ju, Eun Ju Lee
Radiat Oncol J. 2001;19(4):345-352.
PURPOSE: To evaluate the treatment results and prognostic factors after radiotherapy in stage IIB uterine cervix cancer. MATERIALS AND METHODS: We retrospectively analyzed the records of 90 patients with stage IIB uterine cervix cancer who received radiotherapy between 9/94 and 12/99. Age was ranged from 28 to 79 years (median 57). Tumor size was > or = 4 cm in 64...
Bladder Preservation by Combuned Modality Therapy for Invasive Bladder Cancer: A Five-Year Follow-up
Jae Ho Cho, Jihoon Lim, Jinsil Seong, Hong Ryull Pyo, Woong Soup Koom, Chang Ok Suh, Sung Jun Hong
Radiat Oncol J. 2001;19(4):359-368.
No absract available.
The Development of On-Line Statistics Program for Radiation Oncology
Yoon Jong Kim, Dong Hoon Lee, Young Hoon Ji, Dong Han Lee, Chul Ku Jo, Mi Sook Kim, Sung Rul Ru, Seung Hong Hong
Radiat Oncol J. 2001;19(4):369-380.
PURPOSE: By developing on-line statistics program to record the information of radiation oncology to share the information with internet. It is possible to supply basic reference data for administrative plans to improve radiation oncology. MATERIALS AND METHODS: The information of radiation oncology statistics had been collected by paper forms about 52 hospitals in the past. Now, we can input the data...
Inductoin of Radioresistance by Overexpression of Glutathione S-Transferase K1 (hGSTK1) in MCF-7 Cells
Jae Chul Kim, Sei One Shin
Radiat Oncol J. 2001;19(4):381-388.
PURPOSE: This study was conducted to assess the effects of x-irradiation on the expression of the novel glutathione S-transferase K1 gene. MATERIALS AND METHODS: Human glutathione S-transferase K1 (hGSTK1) DNA was purified and ligated to a pcDNA3.1/Myc-His(+) vector for the overexpression of hGSTK1 gene. MCF-7 cells were transfected with or without the recombinant hGSTK1 gene, and irradiated with 6 MV x-ray. After...
The Differentially Expressed Genes by Radiotherapy in the Patients with Uterine Cervix Cancer
Eun Young Seo, Moon June Cho, Jeung Hoon Lee, Young Sook Lee, Myung Hoon Na, Woong Hee Lee, Jun Sang Kim, Jae Sung Kim
Radiat Oncol J. 2001;19(4):389-396.
PURPOSE: To detect differentially expressed genes in the patients with uterine cervical cancer during the radiation therapy. MATERIALS AND METHODS: In patients with biopsy proven uterine cervical cancer, we took a tumor tissue just before radiation therapy and at 40 minutes after external irradiation of 1.8 Gy. Total RNAs isolated from non-irradiated and irradiated tumor tissue samples were analyzed using the...
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