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- Original Articles
- Radiation Dose-escalation Trial for Glioblastomas with 3D-conformal Radiotherapy
- Jae Ho Cho, Chang Geol Lee, Kyoung Ju Kim, Jino Bak, Se Byeoung Lee, Sam Ju Cho, Su Jung Shim, Dok Hyun Yoon, Hee Jong Chang, Tae Gon Kim, Dong Suk Kim, Chang Ok Suh
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Radiat Oncol J. 2004;22(4):237-246.
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PURPOSE: To investigate the effects of radiation dose-escalation on the treatment outcome, complications and the other prognostic variables for glioblastoma patients treated with 3D-conformal radiotherapy (3D-CRT).
MATERIALS AND METHODS: Between Jan 1997 and July 2002, a total of 75 patients with histologically proven diagnosis of glioblastoma were analyzed. The patients who had a Karnofsky Performance Score (KPS) of 60 or higher,... |
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- Induction Chemotherapy Followed by Radiotherapy for Stage IV Hypopharyngeal Cancer
- Ki Mun Kang, Gyu Young Chai, Jin Pyeong Kim, Won Seop Lee
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Radiat Oncol J. 2004;22(4):247-253.
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PURPOSE: Hypopharyngeal cancer is diagnosed at the advanced stage in most cases, which the prognosis known to be poor.
Thus, the efficacy of induction chemotherapy followed by radiotherapy, with regards to the response and survival rate for stage IV hypopharyngeal cancer patients, was examined.
MATERIALS AND METHODS: From July 1998 to February 2000, 18 cases were diagnosedas AJCC stage IV hypopharyngeal cancer... |
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- The Results of Postoperative Radiotherapy for Hypopharyngeal Carcinoma
- Won Taek Kim, Yong Kan Ki, Ji Ho Nam, Dong Won Kim, Byung Ju Lee, Su Gun Wang, Byung Hyun Kyuon
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Radiat Oncol J. 2004;22(4):254-264.
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PURPOSE: This study was carried out to confirm clinical values and limitations of postoperative radiotherapy for hypopharyngeal carcinoma, to evaluate various prognostic factors which may affect to the treatment results and to use these results as fundamental data for making a new treatment strategy.
METHODS AND MATERIALS: A retrospective analysis was performed on 64 previously untreated patients with squamous cell carcinoma... |
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- Role of Postoperative Radiation Therapy in the Management of Cervical Cancer
- Ha Chung Chun, Myung Za Lee
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Radiat Oncol J. 2004;22(4):265-270.
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PURPOSE: To evaluate the effectiveness of postoperative radiation therapy in cervical cancer patients and define the prognostic factors to affect survival rates.
MATERIALS AND METHODS: Eighty one patients with cervical cancer who were treated with postoperative radiation therapy following surgery at our institution between May 1992 and April 2000 were retrospectively analyzed. Forty two patients had stage IB disease, 17 had... |
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- Psychology and Quality of Life in Cancer Patients on Radiation Therapy
- Jong Chul Yang, Woong Ki Chung
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Radiat Oncol J. 2004;22(4):271-279.
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PURPOSE: The object of this study is to investigate sociodemographic and clinical characteristics, psychology, self-esteem and quality of life in cancer patients on radiation therapy and to provide useful information for therapeutic approach to cancer patients on radiation therapy.
MATERIALS AND METHODS: The subjects were 36 patents who had been treated with radiation therapy and 20 normal people.
Sociodemographic information and clinical... |
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- The Protective Effects of Vitamin C on Hepatotoxicity Induced by Radiation
- Kijung Ahn, Sungkwang Park, Heunglae Cho, Kimun Kang, Duckwha Chung, Jinsoon Kang, Gyuyoung Chai
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Radiat Oncol J. 2004;22(4):280-287.
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PURPOSE: This study was carried out to determine the protective effects of vitamin C on the hepatotoxicity induced by radiation.
MATERIALS AND METHODS: The Spraque Dawley rats were randomly divided into 3 groups; the control group, the radiation exposed group, and the radiation and vitamin C-treated group. SOD activity, catalase, malondialdehyde and liver enzymes were analyzed to assess the antioxidant effects... |
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- Feasibility of Reflecting Improvement of Tumor Hypoxia by Mild Hyperthermia in Experimental Mouse Tumors with 18F-Fluoromisonidazole
- Sang wook Lee, Jin Sook Ryu, Seung Joon Oh, Ki Chun Im, Gi Jeong Chen, So Ryung Lee, Do Young Song, Soo Jeong Im, Eun Sook Moon, Jong Hoon Kim, Seung Do Ahn, Seong Soo Shin, Kyeong Ryong Lee, Dae Hyuk Moon, Eun Kyung Choi
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Radiat Oncol J. 2004;22(4):288-297.
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PURPOSE: The aims of this study were to evaluate the change of [18F]fluoromisonidazole ([18F]FMISO) uptake in C3H mouse squamous cell carcinoma-VII (SCC-VII) treated with mild hyperthermia (42oC) and nicotinamide and to assess the biodistribution of the markers in normal tissues under similar conditions.
METHODS AND MATERIALS: [18F]FMISO was producedby our hospital. Female C3H mice with a C3H SCC-VII tumor grown on... |
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- Proteomics of Protein Expression Profiling in Tissues with Different Radiosensitivity
- Jeung Hee An, Jiyoung Kim, Jinsil Seong
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Radiat Oncol J. 2004;22(4):298-306.
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PURPOSE: The purpose of this study was to identify Radiosensitivity of proteins in tissues with different radiosensitivity.
MATERIALS AND METHODS: C3H/HeJ mice were exposed to 10 Gy.
The mice were sacrifiud 8 hrs after radiation. Their spleen and liver tissues were collected and analyzed histologicaly for apoptosis. The expressions of radiosusceptibility protein were analyzed by 2-dimensional electrophoresis and matrix-assisted laser desorption ionization... |
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- Development of Respiration Gating RT Technique using Moving Phantom and Ultrasound Sensor: a feasibility study
- Suk Lee, Sang Hoon Lee, Dongho Shin, Dae Sik Yang, Myung Sun Choi, Chul Yong Kim
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Radiat Oncol J. 2004;22(4):316-324.
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PURPOSE: In radiotherapy of tumors in liver, enough planning target volume (PTV) margins are necessary to compensate breathing-related movement of tumor volumes. To overcome the problems, this study aims to obtain patients' body movements by using a moving phantom and an ultrasonic sensor, and to develop respiration gating techniques that can adjust patients' beds by using reversed values of the... |
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