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Table of Contents | June, 2012  Vol. 30  No.2 Previous Issue | Next Issue | Archive
In this issue:


Original Articles
Clinical Investigation
Therapeutic results and safety of postoperative radiotherapy for keloid after repeated Cesarean section in immediate postpartum period
Juree Kim, Sang Hoon Lee
Radiat Oncol J. 2012;30(2):49-52.   Published online June 30, 2012
Purpose

To evaluate the effectiveness and safety of postoperative radiotherapy for the treatment of keloid scars administered immediately after Cesarean section.

Materials and Methods

A total of 26 postpartum patients with confirmed keloids resulting from previous Cesarean sections received either 12 or 15 Gy radiotherapy. The radiotherapy was divided into three 6 MeV electron beam fractions administered during the postpartum period immediately following...

Clinical application of RapidArc volumetric modulated arc therapy as a component in whole brain radiation therapy for poor prognostic, four or more multiple brain metastases
Seung Heon Lee, Kyu Chan Lee, Jinho Choi, Hye Young Kim, Seok Ho Lee, Ki Hoon Sung, Yunmi Kim
Radiat Oncol J. 2012;30(2):53-61.   Published online June 30, 2012
Purpose

To determine feasibility of RapidArc in sequential or simultaneous integrated tumor boost in whole brain radiation therapy (WBRT) for poor prognostic patients with four or more brain metastases.

Materials and Methods

Nine patients with multiple (≥4) brain metastases were analyzed. Three patients were classified as class II in recursive partitioning analysis and 6 were class III. The class III patients presented with...

Treatment outcome of conservative surgery plus postoperative radiotherapy for extremity soft tissue sarcoma
Jieun Lee, Young Je Park, Dae Sik Yang, Won Sup Yoon, Jung Ae Lee, Chai Hong Rim, Chul Yong Kim
Radiat Oncol J. 2012;30(2):62-69.   Published online June 30, 2012
Purpose

To evaluate the treatment outcome and prognostic factor of postoperative radiotherapy for extremity soft tissue sarcoma (STS).

Materials and Methods

Forty three patients with extremity STS were treated with conservative surgery and postoperative radiotherapy from January 1981 to December 2010 at Korea University Medical Center. Median total 60 Gy (range, 50 to 74.4 Gy) of radiation was delivered and 7 patients were...

Method of tumor volume evaluation using magnetic resonance imaging for outcome prediction in cervical cancer treated with concurrent chemotherapy and radiotherapy
Hun Jung Kim, Woochul Kim
Radiat Oncol J. 2012;30(2):70-77.   Published online June 30, 2012
Purpose

To evaluate the patterns of tumor shape and to compare tumor volume derived from simple diameter-based ellipsoid measurement with that derived from tracing the entire tumor contour using region of interest (ROI)-based 3D volumetry with respect to the prediction outcome in cervical cancer patients treated with concurrent chemotherapy and radiotherapy.

Materials and Methods

Magnetic resonance imaging was performed in 98 patients with...

Biology Contribution
Effect of troglitazone on radiation sensitivity in cervix cancer cells
Zhengzhe An, Xianguang Liu, Hyejin Song, Chihwan Choi, Won-Dong Kim, Jae-Ran Yu, Woo-Yoon Park
Radiat Oncol J. 2012;30(2):78-87.   Published online June 30, 2012
Purpose

Troglitazone (TRO) is a peroxisome proliferator-activated receptor γ (PPARγ) agonist. TRO has antiproliferative activity on many kinds of cancer cells via G1 arrest. TRO also increases Cu2+/Zn2+-superoxide dismutase (CuZnSOD) and catalase. Cell cycle, and SOD and catalase may affect on radiation sensitivity. We investigated the effect of TRO on radiation sensitivity in cancer cells in vitro.

Materials and Methods

Three human cervix...

Fenofibrate decreases radiation sensitivity via peroxisome proliferator-activated receptor α-mediated superoxide dismutase induction in HeLa cells
Xianguang Liu, Seong Soon Jang, Zhengzhe An, Hyejin Song, Won-Dong Kim, Jae-Ran Yu, Woo-Yoon Park
Radiat Oncol J. 2012;30(2):88-95.   Published online June 30, 2012
Purpose

The fibrates are ligands for peroxisome proliferator-activated receptor (PPAR) α and used clinically as hypolipidemic drugs. The fibrates are known to cause peroxisome proliferation, enhance superoxide dismutase (SOD) expression and catalase activity. The antioxidant actions of the fibrates may modify radiation sensitivity. Here, we investigated the change of the radiation sensitivity in two cervix cancer cell lines in combination with...

Letters to the Editor
Erratum: Acknowledgments correction
Wonmo Sung, Jong Min Park, Chang Heon Choi, Sung Whan Ha, Sung-Joon Ye
Radiat Oncol J. 2012;30(2):96-96.   Published online June 30, 2012
Erratum: Acknowledgments correction
BoKyong Kim, Hee Chul Park, Dongryul Oh, Eun Hyuk Shin, Yong Chan Ahn, Jinsung Kim, Youngyih Han
Radiat Oncol J. 2012;30(2):97-97.   Published online June 30, 2012
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