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- Review Article
- Enhancement of radiation effect using beta-lapachone and underlying mechanism
- Ki Jung Ahn, Hyung Sik Lee, Se Kyung Bai, Chang Won Song
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Radiat Oncol J. 2013;31(2):57-65. Published online June 30, 2013
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Beta-lapachone (β-Lap; 3,4-dihydro-2, 2-dimethyl-2H-naphthol[1, 2-b]pyran-5,6-dione) is a novel anti-cancer drug under phase I/II clinical trials. β-Lap has been demonstrated to cause apoptotic and necrotic death in a variety of human cancer cells in vitro and in vivo. The mechanisms underlying the β-Lap toxicity against cancer cells has been controversial. The most recent view is that β-Lap, which is a quinone... |
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- Original Articles
- Clinical Investigation
- Long-term results of ipsilateral radiotherapy for tonsil cancer
- Tae Ryool Koo, Hong-Gyun Wu
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Radiat Oncol J. 2013;31(2):66-71. Published online June 30, 2013
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Purpose We evaluated the effectiveness and safety of ipsilateral radiotherapy for the patient with well lateralized tonsil cancer: not cross midline and <1 cm of tumor invasion into the soft palate or base of tongue. Materials and MethodsFrom 2003 to 2011, twenty patients with well lateralized tonsil cancer underwent ipsilateral radiotherapy. Nineteen patients had T1-T2 tumors, and one patient had T3 tumor;... |
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- Categorizing accident sequences in the external radiotherapy for risk analysis
- Jonghyun Kim
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Radiat Oncol J. 2013;31(2):88-96. Published online June 30, 2013
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Purpose This study identifies accident sequences from the past accidents in order to help the risk analysis application to the external radiotherapy. Materials and MethodsThis study reviews 59 accidental cases in two retrospective safety analyses that have collected the incidents in the external radiotherapy extensively. Two accident analysis reports that accumulated past incidents are investigated to identify accident sequences including initiating events,... |
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- The location of locoregional recurrence in pathologic T3N0, non-irradiated lower rectal cancer
- Mi Sun Kim, Ki Chang Keum, Woo Joong Rhee, Hyunju Kim, Minji Kim, Seohee Choi, Ki Chang Nam, Woong Sub Koom
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Radiat Oncol J. 2013;31(2):97-103. Published online June 30, 2013
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Purpose To investigate the patterns of locoregional recurrence of pathologic T3N0 (pT3N0) lower rectal cancer omitting postoperative radiotherapy (RT) and explore the potential of modification of a RT field. Materials and MethodsFrom Jan 2003 to Nov 2011, 35 patients omitting preoperative or postoperative RT for pT3N0 lower rectal cancer were included. We defined the lower rectal cancer as the tumor with the... |
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- Physics Contribution
- Comparison study of intensity modulated arc therapy using single or multiple arcs to intensity modulated radiation therapy for high-risk prostate cancer
- Hani Ashamalla, Ajay Tejwani, Ioannis Parameritis, Uma Swamy, Pei Ching Luo, Adel Guirguis, Amir Lavaf
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Radiat Oncol J. 2013;31(2):104-110. Published online June 30, 2013
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Purpose Intensity modulated arc therapy (IMAT) is a form of intensity modulated radiation therapy (IMRT) that delivers dose in single or multiple arcs. We compared IMRT plans versus single-arc field (1ARC) and multi-arc fields (3ARC) IMAT plans in high-risk prostate cancer. Materials and MethodsSixteen patients were studied. Prostate (PTVP), right pelvic (PTVRtLN) and left pelvic lymph nodes (PTVLtLN), and organs at risk... |
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