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Table of Contents | December, 2013  Vol. 31  No.4 Previous Issue | Next Issue | Archive
In this issue:


Original Articles
Clinical Investigation
Patterns of care and treatment outcomes for primary thyroid lymphoma: a single institution study
Hyejung Cha, Jun Won Kim, Chang-Ok Suh, Jin Seok Kim, June-Won Cheong, Jeongshim Lee, Ki Chang Keum, Chang Geol Lee, Jaeho Cho
Radiat Oncol J. 2013;31(4):177-184.   Published online December 31, 2013
Purpose

The aim of this study was to analyze the patterns of care and treatment outcomes in patients with primary thyroid lymphoma (PTL) in a single institution.

Materials and Methods

Medical records of 29 patients with PTL treated between April 1994 and February 2012 were retrospectively reviewed. Diagnosis was confirmed by biopsy (n = 17) or thyroidectomy (n = 12). Treatment modality and...

Effect of early chemoradiotherapy in patients with limited stage small cell lung cancer
In-Bong Ha, Bae-Kwon Jeong, Hojin Jeong, Hoon-Sik Choi, Gyu-Young Chai, Myoung-Hee Kang, Hoon Gu Kim, Gyeong-Won Lee, Jae-Beom Na, Ki-Mun Kang
Radiat Oncol J. 2013;31(4):185-190.   Published online December 31, 2013
Purpose

We evaluated the effect of early chemoradiotherapy on the treatment of patients with limited stage small cell lung cancer (LS-SCLC).

Materials and Methods

Between January 2006 and December 2011, thirty-one patients with histologically proven LS-SCLC who were treated with two cycles of chemotherapy followed by concurrent chemoradiotherapy and consolidation chemotherapy were retrospectively analyzed. The chemotherapy regimen was composed of etoposide and cisplatin....

Long-term results of forward intensity-modulated radiation therapy for patients with early-stage breast cancer
Boram Ha, Hyun Suk Suh, Jihae Lee, Kyung-Ja Lee, Rena Lee, Byung In Moon
Radiat Oncol J. 2013;31(4):191-198.   Published online December 31, 2013
Purpose

To observe long-term clinical outcomes for patients with early-stage breast cancer treated with forward intensity-modulated radiation therapy (IMRT), including local control and clinical toxicities.

Materials and Methods

We retrospectively analyzed a total of 214 patients with stage I-II breast cancer who were treated with breast conserving surgery followed by adjuvant breast radiation therapy between 2001 and 2008. All patients were treated using...

Whole pelvic intensity-modulated radiotherapy for high-risk prostate cancer: a preliminary report
Ji Hyeon Joo, Yeon Joo Kim, Young Seok Kim, Eun Kyung Choi, Jong Hoon Kim, Sang-wook Lee, Si Yeol Song, Sang Min Yoon, Su Ssan Kim, Jin-hong Park, Yuri Jeong, Hanjong Ahn, Choung-Soo Kim, Jae-Lyun Lee, Seung Do Ahn
Radiat Oncol J. 2013;31(4):199-205.   Published online December 31, 2013
Purpose

To assess the clinical efficacy and toxicity of whole pelvic intensity-modulated radiotherapy (WP-IMRT) for high-risk prostate cancer.

Materials and Methods

Patients with high-risk prostate cancer treated between 2008 and 2013 were reviewed. The study included patients who had undergone WP-IMRT with image guidance using electronic portal imaging devices and/or cone-beam computed tomography. The endorectal balloon was used in 93% of patients. Patients...

Re-irradiation of unresectable recurrent head and neck cancer: using Helical Tomotherapy as image-guided intensity-modulated radiotherapy
Songmi Jeong, Eun Jung Yoo, Ji Yoon Kim, Chi Wha Han, Ki Jun Kim, Chul Seung Kay
Radiat Oncol J. 2013;31(4):206-215.   Published online December 31, 2013
Purpose

Re-irradiation (re-RT) is considered a treatment option for inoperable locoregionally recurrent head and neck cancer (HNC) after prior radiotherapy. We evaluated the efficacy and safety of re-RT using Helical Tomotherapy as image-guided intensity-modulated radiotherapy in recurrent HNC.

Materials and Methods

Patients diagnosed with recurrent HNC and received re-RT were retrospectively reviewed. Primary endpoint was overall survival (OS) and secondary endpoints were locoregional...

Short-course palliative radiotherapy for uterine cervical cancer
Dong Hyun Kim, Ju Hye Lee, Yong Kan Ki, Ji Ho Nam, Won Taek Kim, Ho Sang Jeon, Dahl Park, Dong Won Kim
Radiat Oncol J. 2013;31(4):216-221.   Published online December 31, 2013
Purpose

The purpose of this retrospective study was to evaluate the efficacy and feasibility of short-course hypofractionated radiotherapy (RT) for the palliation of uterine cervical cancer.

Materials and Methods

Seventeen patients with cancer of the uterine cervix, who underwent palliative hypofractionated 3-dimensional conformal radiotherapy between January 2002 and June 2012, were retrospectively analyzed. RT was delivered to symptomatic lesions (both the primary mass...

Prognostic factors for survivals from first relapse in breast cancer patients: analysis of deceased patients
Haeyoung Kim, Doo Ho Choi, Won Park, Seung Jae Huh, Seok Jin Nam, Jeong Eon Lee, Jin Seok Ahn, Young-Hyuck Im
Radiat Oncol J. 2013;31(4):222-227.   Published online December 31, 2013
Purpose

This study was performed to evaluate prognostic factors for survival from first relapse (SFFR) in stage I-III breast cancer patients.

Materials and Methods

From June 1994 to June 2008, 3,835 patients were treated with surgery plus postoperative radiotherapy and adjuvant chemotherapy for stage I-III breast cancer at Samsung Medical Center. Among them, a total of 224 patients died by June 2009, and...

Physics Contribution
Tumor bed volumetric changes during breast irradiation for the patients with breast cancer
Mi Joo Chung, Young Jin Suh, Hyo Chun Lee, Dae Gyu Kang, Eun Joong Kim, Sung Hwan Kim, Jong Hoon Lee
Radiat Oncol J. 2013;31(4):228-233.   Published online December 31, 2013
Purpose

The aim of this study was to evaluate changes in breast tumor bed volume during whole breast irradiation (WBI).

Materials and Methods

From September 2011 to November 2012, thirty patients who underwent breast-conserving surgery (BCS) followed by WBI using computed tomography (CT) simulation were enrolled. Simulation CT scans were performed before WBI (CT1) and five weeks after the breast irradiation (CT2). The...

Esophageal tolerance to high-dose stereotactic radiosurgery
Bo Mi Lee, Sei Kyung Chang, Seung Young Ko, Seung Hoon Yoo, Hyun Soo Shin
Radiat Oncol J. 2013;31(4):234-238.   Published online December 31, 2013
Purpose

Esophageal tolerance is needed to guide the safe administration of stereotactic radiosurgery (SRS). We evaluated comprehensive dose-volume parameters of acute esophageal toxicity in patients with spinal metastasis treated with SRS.

Materials and Methods

From May 2008 to May 2011, 30 cases in 27 patients with spinal metastasis received single fraction SRS to targets neighboring esophagus. Endpoints evaluated include length (mm), volume (mL),...

The deep inspiration breath hold technique using Abches reduces cardiac dose in patients undergoing left-sided breast irradiation
Ha Yoon Lee, Jee Suk Chang, Ik Jae Lee, Kwangwoo Park, Yong Bae Kim, Chang Ok Suh, Jun Won Kim, Ki Chang Keum
Radiat Oncol J. 2013;31(4):239-246.   Published online December 31, 2013
Purpose

We explored whether the deep inspiration breath hold (DIBH) technique using Abches during left-sided breast irradiation was effective for minimizing the amount of radiation to the heart and lung compared to free breathing (FB).

Materials and Methods

Between February and July 2012, a total of 25 patients with left-sided breast cancer underwent two computed tomography scans each with the DIBH using Abches...

Efficient approach for determining four-dimensional computed tomography-based internal target volume in stereotactic radiotherapy of lung cancer
Seung-Gu Yeo, Eun Seog Kim
Radiat Oncol J. 2013;31(4):247-251.   Published online December 31, 2013
Purpose

This study aimed to investigate efficient approaches for determining internal target volume (ITV) from four-dimensional computed tomography (4D CT) images used in stereotactic body radiotherapy (SBRT) for patients with early-stage non-small cell lung cancer (NSCLC).

Materials and Methods

4D CT images were analyzed for 15 patients who received SBRT for stage I NSCLC. Three different ITVs were determined as follows: combining clinical...

Dosimetric evaluation of Tomotherapy and four-box field conformal radiotherapy in locally advanced rectal cancer
Mina Yu, Hong Seok Jang, Dong Min Jeon, Geum Seong Cheon, Hyo Chun Lee, Mi Joo Chung, Sung Hwan Kim, Jong Hoon Lee
Radiat Oncol J. 2013;31(4):252-259.   Published online December 31, 2013
Purpose

To report the results of dosimetric comparison between intensity-modulated radiotherapy (IMRT) using Tomotherapy and four-box field conformal radiotherapy (CRT) for pelvic irradiation of locally advanced rectal cancer.

Materials and Methods

Twelve patients with locally advanced rectal cancer who received a short course preoperative chemoradiotherapy (25 Gy in 5 fractions) on the pelvis using Tomotherapy, between July 2010 and December 2010, were selected....

Case Reports
Stereotactic body radiotherapy for solitary spine metastasis
Sunyoung Lee, Mison Chun, MiJo Lee
Radiat Oncol J. 2013;31(4):260-266.   Published online December 31, 2013

A clear consensus has not been established regarding the best treatment for solitary bone metastasis. Here, we reviewed the medical records of patients with a controlled primary malignancy who had only solitary spine metastasis without metastasis to the extraspinal bone or viscera and underwent treatment between April 2007 and December 2012 with stereotactic body radiosurgery using CyberKnife, with a total...

A patient who has survived for a long period with repeated radiotherapies for multifocal extrahepatic metastases from hepatocellular carcinoma
Sunmi Jo, Hye Kyung Shim
Radiat Oncol J. 2013;31(4):267-272.   Published online December 31, 2013

Although significant advances in the treatment of intrahepatic lesions, it is reported that the prognosis for patients with hepatocellular carcinoma (HCC) who have extrahepatic metastasis remains poor. We report a patient with lung, liver, brain, bone and subcutaneous metastasis from HCC who has survived more than 7 years maintaining relatively good performance status as a result of repeated therapies. A...

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