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- Review Articles
- Management for locally advanced cervical cancer: new trends and controversial issues
- Oyeon Cho
, Mison Chun
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Radiat Oncol J. 2018;36(4):254-264. Published online December 31, 2018
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This article reviewed new trends and controversial issues, including the intensification of chemotherapy and recent brachytherapy (BT) advances, and also reviewed recent consensuses from different societies on the management of locally advanced cervical cancer (LACC). Intensive chemotherapy during and after radiation therapy (RT) was not recommended as a standard treatment due to severe toxicities reported by several studies. The use... |
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- Natural radioprotectors and their impact on cancer drug discovery
- Vinutha Kuruba
, Pavan Gollapalli
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Radiat Oncol J. 2018;36(4):265-275. Published online December 31, 2018
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Cancer is a complex multifaceted illness that affects different patients in discrete ways. For a number of cancers the use of chemotherapy has become standard practice. Chemotherapy is a use of cytostatic drugs to cure cancer. Cytostatic agents not only affect cancer cells but also affect the growth of normal cells; leading to side effects. Because of this, radiotherapy gained... |
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- Original Articles
- Clinical investigations
- Trends in intensity-modulated radiation therapy use for rectal cancer in the neoadjuvant setting: a National Cancer Database analysis
- Rodney E. Wegner
, Stephen Abel , Richard J. White , Zachary D. Horne , Shaakir Hasan , Alexander V. Kirichenko
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Radiat Oncol J. 2018;36(4):276-284. Published online December 31, 2018
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Purpose: Traditionally, three-dimensional conformal radiation therapy (3D-CRT) is used for neoadjuvant chemoradiation in locally advanced rectal cancer. Intensity-modulated radiation therapy (IMRT) was later developed for more conformal dose distribution, with the potential for reduced toxicity across many disease sites. We sought to use the National Cancer Database (NCDB) to examine trends and predictors for IMRT use in rectal cancer.
Materials and... |
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- Local and regional recurrence following mastectomy in breast cancer patients with 1–3 positive nodes: implications for postmastectomy radiotherapy volume
- Shin-Hyung Park
, Jeeyeon Lee , Jeong Eun Lee , Min Kyu Kang , Mi Young Kim , Ho Yong Park , Jin Hyang Jung , Yee Soo Chae , Soo Jung Lee , Jae-Chul Kim
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Radiat Oncol J. 2018;36(4):285-294. Published online December 31, 2018
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Purpose: To determine the necessity of postmastectomy radiotherapy (PMRT) and which regions would be at risk for recurrence, we evaluated local and regional recurrence in breast cancer patients with 1–3 positive nodes and a tumor size of <5 cm.
Materials and Methods: We retrospectively analyzed data of 133 female breast cancer patients with 1–3 positive nodes, and a tumor size of... |
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- Elective neck treatment in clinically node-negative paranasal sinus carcinomas: impact on treatment outcome
- Won Hee Lee
, Seo Hee Choi , Se-Heon Kim , Eun Chang Choi , Chang Geol Lee , Ki Chang Keum
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Radiat Oncol J. 2018;36(4):304-316. Published online December 31, 2018
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Purpose: The indication of elective neck treatment (ENT) for clinically N0 (cN0) paranasal sinus (PNS) carcinoma remains unclear. We aimed to investigate different treatment outcomes regarding ENT and propose optimal recommendations for ENT.
Materials and Methods: We identified patients with cN0 PNS carcinoma who underwent curative-intent treatment between 1992 and 2015. Survival outcomes and pattern of failure were compared between patients... |
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- Efficacy of adjuvant radiotherapy in non-extremity soft tissue sarcoma with moderate chemosensitivity
- Eun Mi Lee
, Dong Hyun Kim , Do Young Kim , Young Mi Seol , Young Jin Choi , Hyojeong Kim
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Radiat Oncol J. 2018;36(4):325-331. Published online December 31, 2018
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Purpose: Soft tissue sarcoma (STS) is a rare and heterogeneous cancer with over 50 known subtypes. It is difficult to understand the role of adjuvant treatment in STS. We aimed to determine the benefits of adjuvant treatment for a rare STS subset: non- extremity STS with moderate chemosensitivity.
Materials and Methods: We reviewed medical records from Pusan National University Hospital and... |
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- Case Report
- Sinonasal teratocarcinosarcoma treated with surgery followed by volumetric modulated radiotherapy: a case report with review of literature
- Sarthak Tandon
, Munish Gairola , Parveen Ahlawat , Kanika Sharma , Soumitra Barik , Nishtha Sachdeva , Sunil Pasricha , Apeksha Shenoy
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Radiat Oncol J. 2018;36(4):341-347. Published online December 7, 2018
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Surgical excision along with use of postoperative radiotherapy forms an integral management of sinonasal teratocarcinosarcoma (SNTCS). However, given the rarity of the tumor, no standardised guidelines, dose, technique and target delineation exist especially in the era of modern radiation delivery techniques. This is a case of 55-year-old male diagnosed as SNTCS treated with radical ethmoidectomy followed by volumetric modulated radiotherapy,... |
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