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Table of Contents | December, 2022  Vol. 40  No.4 Previous Issue | Next Issue | Archive
In this issue:




Review Article
Journey to hypofractionation in radiotherapy for breast cancer: critical reviews for recent updates
Nalee Kim, Yong Bae Kim
Radiat Oncol J. 2022;40(4):216-224.   Published online December 26, 2022
Historical conventional fractionated radiation therapy (RT) for breast cancer consisted of 1.8–2.0 Gy per fraction with a total dose of 45–60 Gy over 5–7 weeks. Based on radiobiological characteristics, a low α/β is suspected of breast cancer resulting in sensitivity to higher dose per fraction (2.5–3.0 Gy). Over the past 10 years, multiple clinical trials support the application of shorter...
Original Articles
Patterns of failure for hypopharynx cancer patients treated with limited high-dose radiotherapy treatment volumes
Adam Burr, Paul Harari, Aaron Wieland, Randall Kimple, Gregory Hartig, Matthew Witek
Radiat Oncol J. 2022;40(4):225-231.   Published online December 2, 2022

Purpose: Optimal radiotherapy treatment volumes for patients with locally advanced hypopharynx squamous cell carcinoma should ensure maximal tumor coverage with minimal inclusion of normal surrounding structures. Here we evaluated the effectiveness of a direct 3-mm high-dose gross tumor volume to planning target volume expansion on clinical outcomes for hypopharynx cancers. Materials and Methods: We performed a retrospective analysis of...
Stereotactic radiosurgery for limited brain metastasis using three different techniques: helical tomotherapy, volumetric modulated arc therapy, and cone-based LINAC radiosurgery
Bongkot Jia-Mahasap, Chakri Madla, Patumrat Sripan, Imjai Chitapanarux, Ekkasit Tharavichitkul, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan
Radiat Oncol J. 2022;40(4):232-241.   Published online December 26, 2022

Purpose: Specific radiation delivered to tumors by stereotactic radiosurgery (SRS) has become widely used in the treatment of brain metastasis. This study aimed to compare radiation therapy planning and its parameters from SRS using three different modalities: helical tomotherapy (HT), volumetric modulated arc therapy (VMAT), and cone-based linac radiosurgery (Cone-based). Materials and Methods: Each contouring dataset of patents who experienced...
Dosimetric evaluation of magnetic resonance imaging-guided adaptive radiation therapy in pancreatic cancer by extent of re-contouring of organs-at-risk
Jun Yeong Song, Eui Kyu Chie, Seong-Hee Kang, Yeon-Jun Jeon, Yoon-Ah Ko, Dong-Yun Kim, Hyun-Cheol Kang
Radiat Oncol J. 2022;40(4):242-250.   Published online December 26, 2022

Purpose: The safety of online contouring and planning for adaptive radiotherapy is unknown. This study aimed to evaluate the dosimetric difference of the organ-at-risk (OAR) according to the extent of contouring in stereotactic magnetic resonance image-guided adaptive RT (SMART) for pancreatic cancer. Materials and Methods: We reviewed the treatment plan data used for SMART in patients with pancreatic cancer. For the...
Clinical utilization of radiation therapy in Korea between 2017 and 2019
Eunji Kim, Won Il Jang, Kwangmo Yang, Mi-Sook Kim, Hyung Jun Yoo, Eun Kyung Paik, Heejin Kim, Jaesun Yoon, Informatics Committee of the Korean Society for Radiation Oncology
Radiat Oncol J. 2022;40(4):251-259.   Published online December 27, 2022

Purpose: This study aimed to evaluate the clinical infrastructure and utilization of radiotherapy (RT) services in Korea between 2017 and 2019. Materials and Methods: We extracted the data of patients who underwent RT between 2017 and 2019 from the Health Insurance Review and Assessment Service. We further analyzed this data according to the diagnosis and treatment modalities of patients diagnosed...
Feasibility and safety of neck level IB-sparing radiotherapy in nasopharyngeal cancer: a long-term single institution analysis
Dowook Kim, Bhumsuk Keam, Soon-Hyun Ahn, Chang Heon Choi, Hong-Gyun Wu
Radiat Oncol J. 2022;40(4):260-269.   Published online December 26, 2022

Purpose: Nasopharyngeal cancer (NPC) has a higher prevalence of regional nodal metastasis than other head and neck cancers; however, level IB lymph node involvement is rare. We evaluated the safety and feasibility of level IB-sparing radiotherapy (RT) for NPC patients. Materials and Methods: We retrospectively reviewed 236 patients with NPC who underwent definitive intensity-modulated RT with or without chemotherapy between 2004...
Case Report
Diffuse pigmented villonodular synovitis of the knee joint: 3-year follow-up of a case report
Antonios A. Koutalos, Dimitrios Ragias, Emmanouel Rizniotopoulos, Konstantinos Tsanadis, Emmanouil Xydias, Nikolaos Tsoukalas, Nikolaos Charalampakis, Nikolaos Trogkanis, Maria Ioannou, Konstantinos N. Malizos, Maria Tolia
Radiat Oncol J. 2022;40(4):270-275.   Published online December 26, 2022
Pigmented villonodular synovitis (PVNS) is a proliferative, recurrent and locally invasive disease of the synovium. The symptoms of the disorder are not typical and thus it is very often misdiagnosed. Most of the times, magnetic resonance imaging presents the nodular model of development and sets the basis for the diagnosis. The final diagnosis will be set by the pathological evaluation...
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