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- Review Article
- A practical review of watch-and-wait approach in rectal cancer
- Hwa Kyung Byun
 , Woong Sub Koom
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Radiat Oncol J. 2023;41(1):4-11. Published online March 28, 2023
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Rectal resection surgery after neoadjuvant treatment has been the mainstay treatment of locally advanced rectal cancer. However, functional outcomes and quality of life after radical resection of the rectum remain suboptimal. The excellent oncologic outcomes in patients who achieved pathologic complete response after neoadjuvant treatment questioned the need for radical surgery. The watch-and-wait approach is a noninvasive therapeutic alternative for... |
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- Original Articles
- Safety and efficacy of salvage conventional re-irradiation following stereotactic radiosurgery for spine metastases
- Marcus A. Florez
 , Brian De, Bhavana V. Chapman, Anussara Prayongrat, Jonathan G. Thomas, Thomas H. Beckham, Chenyang Wang, Debra N. Yeboa, Andrew J. Bishop, Tina Briere, Behrang Amini, Jing Li, Claudio E. Tatsui, Laurence D. Rhines, Amol J. Ghia
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Radiat Oncol J. 2023;41(1):12-22. Published online March 14, 2023
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Purpose: There has been limited work assessing the use of re-irradiation (re-RT) for local failure following stereotactic spinal radiosurgery (SSRS). We reviewed our institutional experience of conventionally-fractionated external beam radiation (cEBRT) for salvage therapy following SSRS local failure.
Materials and Methods: We performed a retrospective review of 54 patients that underwent salvage conventional re-RT at previously SSRS-treated sites. Local control... |
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- Peripheral blood lymphocyte changes after stereotactic ablative body radiotherapy to lung or liver metastases in patients with oligometastatic cancers
- Sergey Nikolaevich Novikov
 , Irina Aleksandrovna Baldueva, Anton Yurievich Zozulya, Natalya Viktorovna Emelyanova, Dmitriy Viktorovich Girdyuk, Andrey Ivanovich Arsenyev, Elena Alexandrovna, Elena Ivanovna Tyuryaeva, E. I. Filip Evgenevich Antipov, Mikhail Markovich Girshovich, Sergey Vasilevich Kanayev
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Radiat Oncol J. 2023;41(1):23-31. Published online February 27, 2023
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Purpose: To perform the analysis of the peripheral blood lymphocyte changes after stereotactic ablative radiotherapy (SABR) in patients with oligometastatic cancers.
Materials and Methods: The dynamics of the immune status in peripheral blood was prospectively evaluated in 46 patients with lung (17 cases) or liver (29 cases) metastases treated by SABR. Flow cytometry of peripheral blood lymphocyte subpopulations was performed before... |
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- Liquid biopsy using cfDNA to predict radiation therapy response in solid tumors
- Won Kyung Cho, Junnam Lee, Sung-Min Youn, Dongryul Oh, Do Hoon Lim, Han Gyul Yoon, Eun-Hae Cho, Jae Myoung Noh
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Radiat Oncol J. 2023;41(1):32-39. Published online March 28, 2023
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Purpose: This study explored the potential feasibility of cell-free DNA (cfDNA) in monitoring treatment response through the measurement of chromosomal instabilities using I-scores in the context of radiation therapy (RT) for other solid tumors.
Materials and Methods: This study enrolled 23 patients treated with RT for lung, esophageal, and head and neck cancer. Serial cfDNA monitoring was performed before RT, 1... |
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- Low body mass index is associated with poor treatment outcome following radiotherapy in esophageal squamous cell carcinoma
- Ji-young Lee, Yunseon Choi
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Radiat Oncol J. 2023;41(1):40-47. Published online March 22, 2023
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Purpose: We aimed to determine whether patients with esophageal cancer with a low baseline body mass index (BMI) have a poor prognosis following radiotherapy (RT).
Materials and Methods: We retrospectively analyzed data from 50 patients with esophageal cancer to determine whether a low starting BMI (before RT) was associated with a poor outcome. All study participants were diagnosed with non-metastatic esophageal... |
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- Excluding prepontine cistern from whole ventricle radiotherapy target volume in localized germinoma
- Hyejo Ryu, Joo Ho Lee
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Radiat Oncol J. 2023;41(1):48-57. Published online March 28, 2023
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Purpose: The target delineation of whole ventricle radiotherapy (WVRT) in germinoma varies among radiation oncologists, especially regarding the inclusion of the prepontine cistern (PC). We evaluated the outcome of PC-sparing WVRT in localized germinoma.
Materials and Methods: We identified 87 localized intracranial germinoma patients who received radiotherapy (RT) following chemotherapy between 1999 and 2020. By institutional policy, RT for... |
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