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Table of Contents | September, 2023  Vol. 41  No.3 Previous Issue | Next Issue | Archive
In this issue:




Review Article
Exploring the past, present, and future of postoperative radiotherapy for N2 stage non-small cell lung cancer
Byoung Hyuck Kim, Jae Sik Kim, Hak Jae Kim
Radiat Oncol J. 2023;41(3):144-153.   Published online August 23, 2023
Despite conventionally applied postoperative radiotherapy (PORT) in pathological N2 (pN2) stage non-small cell lung cancer (NSCLC) considering high locoregional recurrence, its survival benefit has been a continuous topic of debate. Although several randomized clinical trials have been conducted, many of them have been withdrawn or analyzed without statistical significance due to slow accrual, making it difficult to determine the efficacy...
Original Articles
Comparison of sequential versus concurrent chemoradiation regimens in non-metastatic muscle-invasive bladder cancer
Heidi M. Vieira, David P. Kasper, Runqiu Wang, Lynette M. Smith, Charles A. Enke, Raymond C. Bergan, Benjamin A. Teply, Michael J. Baine
Radiat Oncol J. 2023;41(3):154-162.   Published online September 21, 2023

Purpose: The treatment approach for non-metastatic bladder cancer is guided by an invasion of the muscular layer of the bladder wall. Radical cystectomy is the recommended treatment for muscle-invasive disease. However, it has considerable morbidity and mortality and is not suited for many patients. Trimodality therapy consisting of chemoradiation after transurethral resection of bladder tumor offers a definitive approach with...
Clinical outcomes of radical radiotherapy for pulmonary sarcomatoid carcinoma
Choong-won Lee, Byoung Hyuck Kim, Hak Jae Kim
Radiat Oncol J. 2023;41(3):163-171.   Published online September 14, 2023

Purpose: Pulmonary sarcomatoid carcinoma (PSC) is recognized for its aggressiveness and poor prognosis. The role of radical radiotherapy in PSC remains uncertain due to its scarcity and limited data. In the absence of an effective systemic agent, this study aims to explore the possibility of cure and to investigate potential prognostic factors and treatment outcomes. Materials and Methods: From January...
Application of surface-guided radiation therapy in prostate cancer: comparative analysis of differences with skin marking-guided patient setup
Jaeha Lee, Yeon Joo Kim, Youngmoon Goh, Eunyeong Yang, Ha Un Kim, Si Yeol Song, Young Seok Kim
Radiat Oncol J. 2023;41(3):172-177.   Published online September 18, 2023

Purpose: Surface-guided radiation therapy is an image-guided method using optical surface imaging that has recently been adopted for patient setup and motion monitoring during treatment. We aimed to determine whether the surface guide setup is accurate and efficient compared to the skin-marking guide in prostate cancer treatment. Materials and Methods: The skin-marking setup was performed, and vertical, longitudinal, and lateral couch...
Comparison between 1-week and 2-week palliative radiotherapy courses for superior vena cava syndrome
Jongmoo Park, Jeong Eun Lee
Radiat Oncol J. 2023;41(3):178-185.   Published online September 25, 2023

Purpose: The aim of this study was to evaluate the effectiveness of palliative radiation therapy (RT) for superior vena cava (SVC) syndrome from lung cancer and to compare the 2-week and 1-week schedules. Materials and Methods: A retrospective study was conducted on lung cancer patients with palliative RT for SVC syndrome. Patients received 30 Gy in 10 fractions (2-week group) or...
Feasibility of artificial intelligence-driven interfractional monitoring of organ changes by mega-voltage computed tomography in intensity-modulated radiotherapy of prostate cancer
Yohan Lee, Hyun Joon Choi, Hyemi Kim, Sunghyun Kim, Mi Sun Kim, Hyejung Cha, Young Ju Eum, Hyosung Cho, Jeong Eun Park, Sei Hwan You
Radiat Oncol J. 2023;41(3):186-198.   Published online September 25, 2023

Purpose: High-dose radiotherapy (RT) for localized prostate cancer requires careful consideration of target position changes and adjacent organs-at-risk (OARs), such as the rectum and bladder. Therefore, daily monitoring of target position and OAR changes is crucial in minimizing interfractional dosimetric uncertainties. For efficient monitoring of the internal condition of patients, we assessed the feasibility of an auto-segmentation of OARs on...
Outcome of dose-escalated intensity-modulated radiotherapy for limited disease small cell lung cancer
Eunyeong Yang, Young Seob Shin, Ji Hyeon Joo, Wonsik Choi, Su Ssan Kim, Eun Kyung Choi, Jaeha Lee, Si Yeol Song
Radiat Oncol J. 2023;41(3):199-208.   Published online September 26, 2023

Purpose: An optimal once-daily radiotherapy (RT) regimen is under investigation for definitive concurrent chemoradiotherapy (CCRT) in limited disease small cell lung cancer (LD-SCLC). We compared the efficacy and safety of dose escalation with intensity-modulated radiotherapy (IMRT). Materials and Methods: Between January 2016 and March 2021, patients treated with definitive CCRT for LD-SCLC with IMRT were retrospectively reviewed. Patients who received a...
Developing prompts from large language model for extracting clinical information from pathology and ultrasound reports in breast cancer
Hyeon Seok Choi, Jun Yeong Song, Kyung Hwan Shin, Ji Hyun Chang, Bum-Sup Jang
Radiat Oncol J. 2023;41(3):209-216.   Published online September 21, 2023

Purpose: We aimed to evaluate the time and cost of developing prompts using large language model (LLM), tailored to extract clinical factors in breast cancer patients and their accuracy. Materials and Methods: We collected data from reports of surgical pathology and ultrasound from breast cancer patients who underwent radiotherapy from 2020 to 2022. We extracted the information using the Generative Pre-trained...
Case Report
Bleeding metastasis of renal cell cancer to anal canal treated with radiation
Cemal Ulusoy, Sila Guclu Mete, Andrej Nikolovski
Radiat Oncol J. 2023;41(3):217-221.   Published online September 18, 2023
Renal cell cancer (RCC) has the ability to metastasize to various organs, including the anal canal which is reported to be the rarest location. An 88-year-old male patient who had previously been treated for right RCC subsequently developed distant metastases to the prostate, lungs, and small bowel. Four years following nephrectomy, the patient presented with a bleeding anal mass which...
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