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Table of Contents | , 1991  Vol. 9  No.1 Previous Issue | Next Issue | Archive
In this issue:



Randomized Controlled Trial
IORT in Gastric Cancer
Myung Se Kim, Cheol Hoon Kang, Sung Kyu Kim, Sun Kyo Song, Koing Bo Kwan, Heung Dae Kim
Radiat Oncol J. 1991;9(1):87-92.
Total 28 patients with respectable, locally advanced gastric cancer were entered in our prospective randomized study from June 15, 1988 to Sep. 15, 1990 in Yeungnam University Hospital. This study consisted of curative resection, IORT, external irradiation and combination of chemotherapy. Twenty-four of 28 patients were treated with single dose of 1500 cGy per fraction, 5 days per week was started...
Case Report
Radiation Treatment for Malignant Small Cell Tumor of the Thoracopulmonary RegionPrimitive Pluripotent Histogenesis and Differential Diagnosis: A Case Report and Review of Literatures
Won Young Oh, Jin Yeong Yong, In Soon Whang
Radiat Oncol J. 1991;9(1):117-122.
Malignant small round cell tumor (SRCT) of the thoracopulmonary region appears to originate in the soft tissues of the chest wall or the peripheral lung. A differential diagnosis of poorly differentiated small round cell tumors which include Ewing's sarcoma of bone and soft tissue, embryonal rhabdomyosarcoma, Askin tumor, neuroblastoma, peripheral neuroectodermal tumor, small cell osteogenic sarcoma and lymphoma are after...
Original Articles
Effects of 2-Deoxy-D-Glucose on Metabolic Status, Proliferative Capacity and Growth Rate of FSall Tumor: Observations made by In Vivo 31P-Nuclear Magnetic Resonance Spectroscopy and Flow Cytometry
Hyesook Chang, Eun Kyung Choi, Jeong Gil Cho, Tae Hwan Lim, Tae Keun Lee, Yun Yi, Young Joo Cho, Gon Sup Kim
Radiat Oncol J. 1991;9(1):1-6.
The effect of 2-deoxy-d-glucose (2-DDG) on C3H mouse fibrosarcoma (FSall) was studied. Metabolic status, especially for energy metabolism, was studied using in vivo 31P-MRS, proliferative capacity was observed on flow cytometry (FC) and growth rate was measured after transplantation of 106 viable tumor cells in the dorsum of foot of C3Hf/Sed mice. One gram of 2-DDG per kg of body...
Enhancement of in vivo Radiosensitization by Combination with Pentoxifylline and Nicotinamide
Intae Lee, Moon June Cho
Radiat Oncol J. 1991;9(1):7-16.
Pentoxifylline (PENTO) has been known to improve RBC fluidity, and thus improve the flux of RBC through narrow capillaries. Additionally, PENTO also decreases the O2 release from RBC. Nicotinamide (N4) has been reported to decrease the number of acutely hypoxic cells in tumors by temporarily increasing tumor blood flow. Therefore, the purpose of this study was to examine whether the...
The Effect of Radiation Therapy on the Healing Ability of Subsequent Surgical Wounds
Hyun Suk Suh, Chung Sik Rhee
Radiat Oncol J. 1991;9(1):17-26.
This study was undertaken to find the effect of radiation therapy on the healing ability of surgical wounds and on this basis, to find the proper time interval between the radiation therapy and surgery. Two hundred and fifty-two mice were used and a single dose of 2000 cGy was given in each instances to the hind limb of mice. Incisional...
Interstitial Hyperthermia by Radiofrequency Needle Electrode System: Phantom and Canine Brain Studies
Hyung Sik Lee, Sung Sil Chu, Jin Sil Sung, Chang Ok Suh, Gwi Eon Kim, John J Kyu Loh, Young Soo Kim, Sun Ho Kim, Sang Sup Chung, Eun Kyung Han, Tae Seung Kim
Radiat Oncol J. 1991;9(1):27-36.
No abstract available.
Effects of Radiofrequency Induced local Hyperthermia on Normal Canine Liver
Chang Ok Suh, John Juhn Kyu Loh, Jin Sil Sung, Sun Rock Moon, Hyung Sik Lee, Hyun Soo Shin, Sung Sil Chu, Gwi Eon Kim, Chan Il Park, Eun Kyung Han
Radiat Oncol J. 1991;9(1):37-46.
In order to assess the effects of radiofrequency-induced local hyperthermia on the normal liver, histopathologic findings and biochemical changes after localized hyperthemia in canine liver were studied. Hyperthermia was externally administered using the Thermotron RF-8 (Yamamoto Vinyter Co., Japan; Capacitive type heating machine) with parallel opposed electrodes. Thirteen dogs were used and allocated into one control group (N=3) and two...
The Effect of Radiation Therapy on Oligodendrogliomas
Sei Chul Yoon, Sung Whan Kim, Soo Mi Chung, Hak Jun Gil, Kyung Sub Shinn, Yong Whee Bahk, Joon Ki Kang, Jin Un Song
Radiat Oncol J. 1991;9(1):47-52.
From April, 1983 through April, 1989, we have treated histologically proven 21 patients with oligodendroglima using 6 MV linear accelerator at the Division of Radiation Therapy, Kangnam St. Mary's Hospital Catholic University Medical College. These are 8% of the irradiated 246 primary brain tumors during the same period. To investigate influencing factors on the survival of irradiated 21 patients with...
The Effect of External Radiation Therapy for Intracranial Arteriovenous Malformation: Conventional Radiation Therapy vs Stereotactic Radiosurgery
In Ah Kim, Hong Suk Jang, Mi Ryung You, Sei Chul Yoon, Moon Chan Kim, Kyung Sub Shinn, Yong WHee Bahk
Radiat Oncol J. 1991;9(1):53-58.
From February 1987 through July 1990, the seventeen cases of inoperabelintracranial arteriovenous malformation (AVM) were treated using 6 MV linear accelerator at the Division of Therapeutic Radiology, Kang Nam St. Mary's Hospital. Of seventeen cases, fourteen were male and three were female. Ages ranged from 10 to 51 years (median age of 26 years). The main symptoms were headache, epilepsy and hemiparesis...
Results in the Treatment of Nasopharyngeal Carcinoma Using Combined Radiotherapy
Su Mi Chung, Sei Chul Yoon, Kyung Sub Shinn, Yong Whee Bahk, Hoon Kyo Kim, Kyung Shik Lee, Seung Ho Cho
Radiat Oncol J. 1991;9(1):59-64.
Thirty-one patients with previously untreated and locally advanced nasopharyngeal caner were retrospectively reviewed for comparing the effects of radical radiotherapy alone with that of combining chemotherapy and radiotherapy from 1983 to 1989 at Kangnam St. Mary's Hospital. 23/31 were evaluable for recurrence and survival. There were 8 patients for stageIII , and 15 patients for stageIV. Eleven patients were treated...
Distant Metastases of Nasopharyngeal Carcinoma after Definite Irradiation
Eun Ji Chung, Hyung Sik Lee, Sun Rock Moon, Gwi Eon Kim, John J Kyo Loh
Radiat Oncol J. 1991;9(1):65-72.
One hundred and thirty five patients with carcinoma of the nasopharyx were treated by radiation therapy in the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University between August 1977 and July 1987. Of the 30 patients omitted: 8 had distant metastases at initial diagnosis or during radiotherapy; 18 patients refused or did not received a full course of radiation...
Treatment Result in Advanced T3 and T4 Glottic Carcinoma: YUMC Experience
Hyun Soo Shin, Hyung Sik Lee, Eun Ji Chung, Gwi Eon Kim, Juhn Kyu Loh, Chang Ok Suh, Kwang Moon Kim, Won Pyo Hong
Radiat Oncol J. 1991;9(1):73-80.
Between January 1980 and September 1988, 68 patients with advanced T3 & T4 glottic carcinoma were treated with RT and surgery/RT in the Department of Radiation Oncology, Yonsei Cancer Center and ENT, Yonsei University College of Medicine. The mean age was 60 years old (range 33 to 79 year old). The 34 patients were treated with irradiation alone, and the...
Discrimination of Postradiotherapy Lung Fibrosis from Recurrence by Gallium-67 Scan in Lung Cancer
Samuel Ryu, Jae Tae Lee
Radiat Oncol J. 1991;9(1):81-86.
The differentiation between post-radiotherapy lung fibrosis and tumor recurrence is often a dilemma to physicians. Twenty two patients with lung cancer who had received 45~60 Gy to the chest were chosen to study the possible role of gallium-67 scan. Seventeen squamous cell carcinomas were treated with only radiotherapy, 3 small cell carcinomas with combination chemotherapy, 2 adenocarcinomas with lobectomy. A total of...
The Role of Postoperative Pelvic Radiation Therapy in Rectal Cancer
Yong Chan Ahn, Jae Sung Kim, Hyong Geun Yun, Sung Whan Ha, Charn Il Park
Radiat Oncol J. 1991;9(1):93-102.
To evaluate the role of postoperative pelvic radiation therapy in rectal cancer, a retrospective analysis was done on 189 patients with modified Astler-Coller stages B2+3, C1, and C2+3 who were treated from February 1979 to June 1986. Forty-seven patients were staged as B2+3, 17 as C1, and 125 as C2+3. As a curative resection, 41 received low anterior resection, 143 received...
The Role of Radiotherapy in StageI, II Intermediate Grade Non-Hodgkin's Lymphoma
Hyong Geun Yun, Il Han Kim, Heung Tae Kim, Yong Chan Ahn, Jae Sung Kim, Sung Whan Ha, Charn Il Park
Radiat Oncol J. 1991;9(1):103-110.
Radiotherapy result of 162 patients with stage I, II Intermediate Grade Non-Hodgkin's lymphoma was analyzed to clarify the role and limit of radiotherapy. Of 68 initial failures, 38.2% stageI was 30.0% and 70.0%, respectively with involved field treatment and was 43.8% and 56.2% with extended field treatment, respectively; in stageII, was 16.7% and 83.3%, 41.7% and 58.3% and 40.4% for...
Primary Radiation Therapy of Polymorhic Reticulosis
Jae Sung Kim, Yong Chan Ahn, Hyoung Geun Yun, Charn Il Park
Radiat Oncol J. 1991;9(1):111-116.
From 1979 to 1987, 33 patients with polymorphic retrculosis (PMR) limited in the upper airway were treated with primary radiation therapy and the analysis of treatment results was undertaken. Systemic symptoms such as fever, night sweats, and weight loss were noted in 48%. The nasal cavity was most frequently involved (85%), although involvement of PNS (33%) and palate (30%) was...
Design and Dose Distribution of Docking Applicator for an Intraoperative Radiation Thherapy
Sung Sil Chu, Gwi Eon Kim, John J L Loh
Radiat Oncol J. 1991;9(1):123-130.
A docking intraoperative electron beam applicator system, which is easily docking in the collimator for a linear accelerator after setting a sterilized transparent cone on the tumor bearing area in the operation room, has been designed to optimize dose distribution and to improve the efficiency of radiation treatment method with linear accelerator. This applicator system consisted of collimator holder with...
Characteristics of 15 MV Photon Beam from a Varian Clinac 1800 Dual Energy Linear Accelerator
Kye Jun Kim, Jong Young Lee, Kyung Ran Park
Radiat Oncol J. 1991;9(1):131-142.
A comprehensive set of dosimetric measurements has been made on the Varian Clinac 1800 15 MV photon beam. Beam quality percentage depth dose, dose in the build up region, output, symmetry and flatness, transmission through lead (Cerrobend), tray attenuation, isodose curves for the open and wedged fields were measured using 3 dimensional water phantom dosimetry system (including film densitometer system) and...
Measurement of Dose Distribution in Small Beams of Philips 6 and 8 MVX Linear Accelerator
Tae Suk Suh, Sei Chul Yoon, Kyung Sub Shinn, Yong Whee Bank
Radiat Oncol J. 1991;9(1):143-152.
The work suggested in this paper addresses a method for collecting beam data for small circular fields. Beam data were obtained from Philips 6 and 8 MV LINAC at Dept. Radiation Therapy at Gainesville Incorporated and Shands Teaching Hospital. Specific quantities measured include tissue maximum ratio (TMR), off-axis ration (OAR) and relative output factor (ROF). In small field irradiation, special collimators...
Physical Aspect of The Gamma Knife and Its Clinical Application
Byong Yong Yi, Hyesook Chang, Eunkyung Choi, C Jin Whang, Y Kwon
Radiat Oncol J. 1991;9(1):153-158.
The first Leksell Gamma Knife unit(LGU-type B) for radiosurgery in Asia was installed in Asan Medical Center. Mechanical accuracy, output, dose profiles for each collimators were measure during acceptance test. Sixty eight patients (sixty nine cases) had undergone radiosurgery from May 1990 to September 1990. AVM cases were 24 cases (35%), acoustic tumor 10 (14%), pituitary adenoma 4 (6%), metastatic tumor...
A New Technique for Whole Craniospinal Irradiation (WCSI)
Hyesook Chang
Radiat Oncol J. 1991;9(1):159-164.
To irradiate the entire neuroaxis, bilateral parallel opposed brain fields and direct posterior spinal field have been utilized and radiation dose at the junction between abutting fields has been extensilvely studied. And several workable methods were reported to achieve uniform dose at a desired depth at the junction between abutting fields whose central axis are coplanar. But the dose distribution...
Modified Five Field Technique for Primary and Postop Breast Cancer Irradiation
Eunkyung Choi, Hyesook Chang, Byong Yong Yi
Radiat Oncol J. 1991;9(1):165-170.
In breast cancer, the treatment volume presents a relatively complex three dimensional structure. Effective radiation therapy requires the delivery of adequate dose to a large target volume using complex beam arrangements. The technique proposed here is our department's method using asymmetric jaw with appropriate couch, collimator and gantry rotation. This technique has the following advantages: 1) all treatments are given in...
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