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- Original Articles
- Enhanced Radiosensitivity of Tumor Cells Treated with Vanadate in Vitro
- Myung Za Lee, Won Young Lee
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Radiat Oncol J. 1994;12(2):129-142.
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Intracellular ions which have a major role in cellular function have been reported to affect repair of radiation damage. Recently it has been reported that ouabain sensitizes A549 tumor cells hut not CCL-120 normal cells to radiation. Ouabain inhibits the Na+-K+-pump rapidly thus it increases intracellular Na concentration. Vanadate which is distributed extensively in almost all living organisms in known... |
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- Pathologic Changes in the Rabbit lung Following Single Dose irradiation
- Hyung Sik Lee, Young Min Choi, Won Joo Hur, Jin Sook Jeong, Young Hyun Yuh, Ki Nam Lee
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Radiat Oncol J. 1994;12(2):143-150.
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The damage which radiation produces in tissues such as the lungs can be discussed at the molecular, biophysical, cellular, and organ levels. The cellular effects of irradiating the lungs are related to the histologic and clinical sequelae. In the present study the right lung of rabbits were exposed to single dose of 20 Gy of X-irradiation. Animals from each group... |
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- Multiple Daily Fractionated RT for Malignant Glioma
- Kang Mo Yang, Hye Sook Chang, Seoung Do Ahn, Eun Kyung Choi
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Radiat Oncol J. 1994;12(2):151-158.
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Since Jan. 1992, authors have conducted a pilot study to treat malignant glioma with multiple daily fractionated (MDF) radiation therapy and this paper presents the outcome compared MDF to conventional fractionated (CF) radiation therapy. Between Sep. 1989 and Jan. 1993, forty-three patients with high grade glioma of brain except brain stem glioma were treated: nineteen patients were treated with CF... |
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- The Role of Postoperative Radiotherapy in the Management of Intracranial Meningiomas
- Sei Kyung Chang, Chang Ok Suh, Hyun Soo Shin, Gwi Eon Kim
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Radiat Oncol J. 1994;12(2):159-164.
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PURPOSE: To evaluate the role of postoperative radiotherapy in the management of primary or recurrent intracranial meningiomas.
METHODS AND MATERIALS: A retrospective review of 34 intracranial meningioma patients referred to the Yonsei Cancer Center for postoperative radiotherapy between 1981 and 1990 was undertaken. Of the 34 patients, 24 patients received elective postoperative radiotherapy after total or subtotal resection(Group 1), and 10... |
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- Accelerated Fractionation In The Treatment of Brain Metastasis From Non-Small Cell Carcinoma of The Lung
- Seong Eon Hong
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Radiat Oncol J. 1994;12(2):165-174.
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PURPOSE: Metastatic cancer to the brain is a major problem for the patients with bronchogenic carcinoma, and most of these patients have a limited survival expectancy. To increase tumor control and/or to decrease late morbidity with possible shortening in over-all treatment period, multiple daily fraction technique for brain metastasis was performed. The author represented the results of accelerated fractionation radiotherapy... |
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- The Results of Radiation Therapy in Non-Small Cell Lung Cancer
- Chul Seung Kay, Hong Seok Jang, Hack Jun Gil, Kyung Sub Shinn
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Radiat Oncol J. 1994;12(2):175-184.
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From March 1983 through January 1990, two hundred sixty six patients with non-mall cell lung cancer were treated with external radiation therapy at the Department of Therapeutic Radiology, Kangnam St. Mary's Hospital, Catholic University Medical College. A retrospective analysis was performed on eligible 116 patients who had been treated with radiation dose over 40 Gy and had been able to... |
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- The Result of Radiation Therapy in the Esophageal Cancer
- Seog Young Choi, Hach Ung Chun, Myung Za Lee
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Radiat Oncol J. 1994;12(2):185-190.
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PURPOSE: Patients with esophageal cancer treated with surgery plus postoperative radiotherapy or radiation alone were retrospectively analyzed.
METHOD: From August 1986 to June 1992, 93 patients who were treated with 30 Gy or more in the Department of Therapeutic Radiology were evaluated. Median age was 59 years. Ninety one were male and remaining 2 were female. Patients with stage II,III, and... |
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- Therapeutic Effect of Combined Radiotherapy and Hyperthermia in Primary Hepatocellular Carcinoma
- Ki Mun Kang, Ihl Bohng Choi, Chul Seung Kay, Byung Ok Choi, Su Mi Chung, In Ah Kim, Sung Tae Han, Hee Sik Sun, Kyu Won Chung, Keyong Sub Shinn
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Radiat Oncol J. 1994;12(2):191-200.
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PURPOSE: This study was undertaken to show the clinical results of combined radiotherapy and hyperthermia in primary hepatoma.
MATERIALS AND METHODS: Between December 1989 and March 1993, 50 patients with hepatomas were treated by combined radiotherapy and hyperthermia. Among them, we analyzed retrospectively 33 patients who received the complete course of treatment. The ages of the patients ranged from 36 to... |
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- The Palliative Radiotherapy in Bone Matastases
- Young Min Choi, Hyung Sik Lee, Won Joo Hur
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Radiat Oncol J. 1994;12(2):201-208.
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To objectively compare the response of the palliative radiotherapy in bone metastatic patients which decreases pain and prevents pathologic fractures, we introduced and applied the RTOG pain and narcotic measure system. From Oct in 1991 to July in 1993, thirty-two patients with painful bone metastases, 17 of them were solitary lesions and others were multiple lesions, were treated with mainly... |
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- Total Body Irradiation for Allogeneic Bone Marrow Transplantation in Chronic Myelogenous Leukemia
- Su Mi Chung, Ihl Bohng Choi, Ki Mun Kang, In Ah Kim, Kyung Sub Shinn, Choon Choo Kim, Dong Jip Kim
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Radiat Oncol J. 1994;12(2):209-218.
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Between July 1987 and December 1992, we treated 22 patients with chromic myelogenous leukemia; 14 in the chronic phase and 8 with more advanced disease. All were received with allogeneic bone marrow transplantation from HLA-identical sibling donors after a total body irradiation (TBI) cyclophosphamide conditioning regimen. Patients were non-randomly assigned to either 1200 cGy/6fractions/3days (6 patients) or 1320 cGy/8 fractions/4days... |
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- Total Body Irradiation Technique: Basic Data Measurements and In Vivo Dosimetry
- Dong Rak Choi, Ihl Bohng Choi, Ki Mun Kang, Kyung Sub Shinn, Choon Choo Kim
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Radiat Oncol J. 1994;12(2):219-224.
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This paper describes the basic date measurements for total body irradiation with 6 Mv photon beam including compensators designs. The technique uses bilateral opposing field with tissue compensators for the head, neck, lungs, and legs from the hip to toes. In vivo dosimetry was carried out for determining absorbed dose at various regions in 7 patients using diode detectors (MULTIDOSE,... |
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- The Dosimetric Data of 10 MV Linear Accelerator Photon Beam for Total Body Irradiation
- Sung Ja Ahn, Wee Saing Kang, Seung Jin Park, Taek Keun Nam, Woong Ki Chung, Byung Sik Nah
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Radiat Oncol J. 1994;12(2):225-232.
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PURPOSE: This study was to obtain the basic dosimetric data using the 10 MV X-ray for the total body irradiation.
MATERIALS AND METHODS: A linear accelerator photon beam is planned to be used as a radiation source for total body irradiation (TBI) in Chonnam University Hospital. The planned distance from the target to the midplane of a patient is 360cm and... |
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- Utilization of Tissue Compensator for Uniform Dose Distribution in Total Body Irradiation
- Seung Jin Park, Woong Ki Chung, Sung Ja Ahn, Taek Keun Nam, Byung Sik Nah
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Radiat Oncol J. 1994;12(2):233-242.
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PURPOSE: This study was performed to verify dose distribution with the tissue compensator which is used for uniform dose distribution in total body irradiation (TBI).
MATERIALS AND METHODS: The compensators were made of lead (0.8mm thickness) and aluminum(1mm or 5mm thickness) plates.
The humanoid phantom of adult size was made of paraffin as a real treatment position for bilateral total body technique.
The... |
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- Optimization of Dose Distribution for High Dose Rate Intraluminal Therapy
- Sung Sil Chu, Gwi Eon Kim, Juhn Kyu Loh
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Radiat Oncol J. 1994;12(2):243-252.
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The use of high dose rate remote afterloading system for the treatment of intraluminal lesions necessitates the need for a more accurate of dose distributions around the high intensity brachytherapy sources, doses are often prescribed to a distance of few centimeters from the linear source, and in this range the dose distribution is very difficult to assess. Accurated and optimized... |
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- Analysis of Radiation Field and Block Pattern for Optimal Size in Multileaf Collimator
- Seoung Do Ahn, Kwang Mo Yang, Byong Yong Yi, Eun Kyong Choi, Hye Sook Chang
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Radiat Oncol J. 1994;12(2):253-262.
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The patterns of the conventional radiation treatment fields and their shielding blocks are analysed to determine the optimal dimension of the MultiLeaf Collimator (MLC) which is considered as an essential tool for conformal therapy. Total 1169 radiation fields from 303 patients (203 from Asan Medical center, 50 from Baek Hosp and 50 from Hanyang Univ.
Hosp.) were analysed for this study.... |
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- Dosimetry of Irregular Field Using Thermoluminescence Dosimetry
- Jong Young Lee, Kyung Ran Park, Kye Jun Kim
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Radiat Oncol J. 1994;12(2):263-267.
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In clinical radiotherapy, the use of wide and irregular field techniques frequently results in considerable tumor dose inhomogeneity because of, the variation in physical characteristics of irradiated volumes. This report describes an analysis of the dosimetry of the irregular fields such as radiation fields for Hodgkin's disease(mantle filed), esophageal cancer, and lung cancer when a 6 MV and a 15... |
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