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Table of Contents | , 2003  Vol. 21  No.4 Previous Issue | Next Issue | Archive
In this issue:

Original Articles
Postoperative Radiation Therapy for Chest Wall Invading pT3N0 Non-small Cell Lung Cancer: Elective Lymphatic Irradiation May Not Be Necessary
Young Je Park, Yong Chan Ahn, Do Hoon Lim, Won Park, Kwan Min Kim, Jhin gook Kim, Young Mog Shim, Kyoung Joo Kim, Jeong Eun Lee, Min Kyu Kang, Hee Lim Nam, Seung Jae Huh
Radiat Oncol J. 2003;21(4):253-260.
PURPOSE: No general consensus has been reached regarding the necessity of postoperative radiation therapy (PORT) and the optimal techniques of its application for patients with chest wall invasion (pT3cw) and node negative (N0) non-small cell lung cancer (NSCLC). We retrospectively analyzed the pT3cwN0 NSCLC patients who received PORT because of presumed inadequate resection margin on surgical findings. MATERIALS AND METHODS: From...
Results of Curative Treatment for Cancer of the Tonsil
Won Park, Yong Chan Ahn, Do Hoon Lim, Chung Whan Baek, Young Ik Son, Keun chil Park, Kyoung Ju Kim, Jeong Eun Lee, Min Kyu Kang, Young Je Park, Hee Rim Nam, Seung Jae Huh
Radiat Oncol J. 2003;21(4):261-268.
PURPOSE: To report the results of curative treatment for patients with tonsil cancer by retrospective analysis. MATERIALS AND METHODS: From Jan. 1995 till Dec. 2000, 27 patients with squamous cell carcinoma of the tonsil received curative treatment at Samsung Medical Center. Therapeutic decision was made through multidisciplinary conference, and curative radiation therapy was favored when, (1) the patient's condition was not...
Radiotherapy for Nasopharyngeal Carcinoma
Myung Za Lee, Ha Chung Chun
Radiat Oncol J. 2003;21(4):269-275.
PURPOSE: To evaluate the results of radiation management on recurrence, survival and prognostic factors of patients with nasopharyngeal cancer. MATERIALS AND METHODS: Forty-nine patients, treated for nasopharyngeal cancer by radiotherapy between January 1984 and June 2000, were retrospectively studied. All patients were followed up for at least 2.5 years. Their median age was 52 years (range 17~78). The histological types were...
Prediction of Late Rectal Complication Following High-dose-rate Intracavitary Brachytherapy in Cancer of the Uterine Cervix
Jeung Eun Lee, Seung Jae Huh, Won Park, Do Hoon Lim, Yong Chan Ahn
Radiat Oncol J. 2003;21(4):276-282.
PURPOSE: Although high-dose-rate intracavitary radiotherapy (HDR ICR) has been used in the treatment of cervical cancer, the potential for increased risk of late complication, most commonly in the rectum, is a major concern. We have previously reported on 136 patients treated with HDR brachytherapy between 1995 and 1999. The purpose of this study is to upgrade the previous data and...
Long Term Follow Up Results of Serum Squamous Cell Carcinoma Antigen Level in Uterine Cervix Cancer Treated by Radiotherapy
Hyong Geun Yun
Radiat Oncol J. 2003;21(4):283-290.
PURPOSE: To evaluate the long term significance of the squamous cell carcinoma (SCC) antigen (Ag) as a tumor marker in uterine cervix carcinoma. MATERIALS AND METHODS: The SCC antigen levels of pre-radiotherapy and serial post-radiotherapy serum were analyzed in 48 patients who received radiotherapy with histologically proven primary SCC of the uterine cervix. RESULTS: Pre-radiotherapy SCC Ag level was high (>or=2 ng/ml)...
A Web-based 'Patterns of Care Study' System for Clinical Radiation Oncology in Korea: Development, Launching, and Characteristics
Il Han Kim, Eui Kyu Chie, Do Hoon Oh, Chang Ok Suh, Jong Hoon Kim, Yong Chan Ahn, Won Joo Hur, Woong Ki Chung, Doo Ho Choi, Jae Won Lee
Radiat Oncol J. 2003;21(4):291-298.
PURPOSE: We report upon a web-based system for Patterns of Care Study (PCS) devised for Korean radiation oncology. This PCS was designed to establish standard tools for clinical quality assurance, to determine basic parameters for radiation oncology processes, to offer a solid system for cooperative clinical studies and a useful standard database for comparisons with other national databases. MATERIALS AND METHODS:...
Investigation of Study Items for the Patterns of Care Study in the Radiotherapy of Laryngeal Cancer: Preliminary Results
Woong Ki Chung, Il Han Kim, Sung Ja Ahn, Taek Keun Nam, Yoon Kyeong Oh, Ju Young Song, Byung Sik Nah, Gyung Ai Chung, Hyoung Cheol Kwon, Jung Soo Kim, Soo Kon Kim, Jeong Ku Kang, Moon June Cho, Jun Sang Kim, Sun Rock Moon, Weon Kuu Chung, Woo Yoon Park, Won Dong Kim, Eun Seog Kim, Hyong Geun Yun, Jae Sung Kim
Radiat Oncol J. 2003;21(4):299-305.
PURPOSE: In order to develop the national guide-lines for the standardization of radiotherapy we are planning to establish a web-based, on-line data-base system for laryngeal cancer. As a first step this study was performed to accumulate the basic clinical information of laryngeal cancer and to determine the items needed for the data-base system. MATERIALS AND METHODS: We analyzed the clinical data...
Regulatory Mechanism of Radiation-induced Cancer Cell Death by the Change of Cell Cycle
Soo Jin Jeong, Min Ho Jeong, Ji Yeon Jang, Wol Soon Jo, Byung Hyouk Nam, Min Za Jeong, Young Jin Lim, Byung Gon Jang, Seon Min Youn, Hyung Sik Lee, Won Joo Hur, Kwang Mo Yang
Radiat Oncol J. 2003;21(4):306-314.
PURPOSE: In our previous study, we have shown the main cell death pattern induced by irradiation or protein tyrosine kinase (PTK) inhibitors in K562 human myelogenous leukemic cell line. Death of the cells treated with irradiation alone was characterized by mitotic catastrophe and typical radiation-induced apoptosis was accelerated by herbimycin A (HMA). Both types of cell death were inhibited by...
Radiation-induced Apoptosis in Developing Fetal Rat Cerebral Cortex
Woong Ki Chung, Taek Keun Nam, Min Cheol Lee, Sung Ja Ahn, Ju Young Song, Seung Jin Park, Byung Sik Nah
Radiat Oncol J. 2003;21(4):315-321.
PURPOSE: This study was performed to investigate apoptosis by radiation in the developing fetal rat brain. MATERIALS AND METHODS: Fetal brains were irradiated in utero between the 17th and 19th days of fetal life (E17-19) by linear accelerator. A dose of irradiation ranging from 1 Gy to 4 Gy was used to evaluate dose dependency. To test time dependency the rats...
Consideration of Surface Dose and Depth of Maximum Dose Using Various Detectors for High Energy X-rays
Yong Ha Lee, Kyung Ran Park, Jong Young Lee, Ik Jae Lee, Young Woo Vahc, Kang Kyoo Lee
Radiat Oncol J. 2003;21(4):322-329.
PURPOSE: It is difficult to exactly determine the surface dose and the dose distribution in buildup region of high energy X-rays by using the conventional ion chamber. The aim of this study is to evaluate the accuracy of widely used dosimetry systems to measure the surface dose and the depth of maximum dose (dmax). MATERIALS AND METHODS: We measured the percent...
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