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- Original Articles
- Analysis of the Causes of Subfrontal Recurrence in Medulloblastoma and Its Salvage Treatment
- Jae Ho Cho, Woong Sub Koom, Chang Geol Lee, Kyoung Ju Kim, Su Jung Shim, Jino Bak, Kyoungkeun Jeong, Tae Gon Kim, Dong Seok Kim, Joong Uhn Choi, Chang Ok Suh
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Radiat Oncol J. 2004;22(3):165-176.
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PURPOSE: Firstly, to analyze factors in terms of radiation treatment that might potentially cause subfrontal relapse in two patients who had been treated by craniospinal irradiation (CSI) for medulloblastoma. Secondly, to explore an effective salvage treatment for these relapses.
MATERIALS AND METHODS: Two patients who had high-risk disease (T3bM1, T3bM3) were treated with combined chemoradiotherapy. CT-simulation based radiation-treatment planning (RTP) was... |
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- Sequential Chemoradiotherapy for Stage I/II Nasal Natural Killer/T Cell Lymphoma
- Young Joo Noh, Yong Chan Ahn, Won Seog Kim, Young Hyeh Ko
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Radiat Oncol J. 2004;22(3):177-183.
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PURPOSE: Authors would report the results of sequential CHOP chemotherapy (cyclophosphamide, adriamycin, vincristine, and prednisone) and involved field radiotherapy (IFRT) for early stage nasal natural killer/T-cell lymphoma (NKTCL).
MATERIALS AND METHODS: Fourteen among 17 patients, who were registered at the Samsung Medical Center tumor registry with stage I and II nasal NKTCL from March 1995 to December 1999 received this treatment... |
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- The National Survey of Breast Cancer Treatment Pattern in Korea (1998): The Use of Breast-Conserving Treatment
- Hyun Soo Shin, Hyung Sik Lee, Sei Kyung Chang, Eun Ji Chung, Jin Hee Kim, Yoon Kyung Oh, Mi Sun Chun, Seung Jae Huh, John Jun Kyu Loh, Chang Ok Suh
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Radiat Oncol J. 2004;22(3):184-191.
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PURPOSE: In order to improve the proper use of radiotherapy and breast-conserving treatment (BCT) in the management of breast cancer, current status of breast cancer treatment in Korea was surveyed nationwide and the use of BCT were evaluated.
MATERIALS AND METHODS: Patients characteristics and treatment pattern of 1048 breast cancer patients from 27 institutions diagnosed between January, 1998 and June, 1998... |
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- The 1998, 1999 Patterns of Care Study for Breast Irradiation After Breast-Conserving Surgery in Korea
- Chang Ok Suh, Hyun Soo Shin, Jae Ho Cho, Won Park, Seung Do Ahn, Kyung Hwan Shin, Eun Ji Chung, Ki Chang Keum, Sung Whan Ha, Sung Ja Ahn, Woo Cheol Kim, Myung Za Lee, Ki Jung Ahn, Doo Ho Choi, Jin Hee Kim, Kyung Ran Park, Kang kyoo Lee, Seunghee Kang, Mi Hee Song, Do Hoon Oh, Jae Won Lee, II Han Kim
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Radiat Oncol J. 2004;22(3):192-199.
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PURPOSE: To determine the patterns of evaluation and treatment in the patient with early breast cancer treated with conservative surgery and radiotherapy and to improve the radiotherapy techiniques, nationwide survey was performed.
MATERIALS AND METHODS: A web-based database system for Korean Patterns of Care Study (PCS) for 6 common cancers was developed. Two hundreds sixty-one randomly selected records of eligible patients... |
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- Expression of Ku Correlates with Radiation Sensitivities in the Head and Neck Cancer Cell Lines
- Sang wook Lee, Eunsil Yu, So Lyoung Yi, Se Hee Son, Jong Hoon Kim, Seung Do Ahn, Seong Soo Shin, Eun Kyung Choi
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Radiat Oncol J. 2004;22(3):208-216.
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PURPOSE: DNA-dependent protein kinase (DNA-PK) is a serine/threonine kinase consisting of a 470 kDa catalytic subunit (DNA-PKcs) and a heterodimeric regulatory complex, called Ku, which is composed of 70 kDa (Ku 70) and 86 kDa (Ku 80) proteins. The DNA-PK has been shown to play a pivotal role in rejoining DNA double-strand-breaks (dsb) in mammalian cells. The purpose of this... |
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- The Expression of Hypoxia Inducible Factor-1alpha by Desferrioxamine Induces Radioresistance in Mouse Hepatoma Cell Line
- Byung Hyun Kwon
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Radiat Oncol J. 2004;22(3):217-224.
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PURPOSE: It is well known that the radiosensitivity of tumor cells can be significantly reduced under hypoxic conditions.
Hypoxia-inducible factor-1alpha (HIF-1alpha) plays a pivotal role in the essential adaptive responses to hypoxia.
Therefore this study investigated the relationship between HIF-1alpha expression and radiosensitivity.
MATERIALS AND METHODS: Mouse hepatoma cell line hepa1c1c7 and HIF-1beta-deficient mutant cell line hepa1C4 were used to analyze the role... |
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