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Table of Contents | September, 2011  Vol. 29  No.3 Previous Issue | Next Issue | Archive
In this issue:



Review Article
Basics of particle therapy I: physics
Seo Hyun Park, Jin Oh Kang
Radiat Oncol J. 2011;29(3):135-146.   Published online September 30, 2011

With the advance of modern radiation therapy technique, radiation dose conformation and dose distribution have improved dramatically. However, the progress does not completely fulfill the goal of cancer treatment such as improved local control or survival. The discordances with the clinical results are from the biophysical nature of photon, which is the main source of radiation therapy in current field,...

Original Articles
Clinical Investigation
Radiation-induced brain injury: retrospective analysis of twelve pathologically proven cases
Dong-Soo Lee, Mina Yu, Hong-Seok Jang, Yeon-Sil Kim, Byung-Ock Choi, Young-Nam Kang, Youn-Soo Lee, Dong-Chul Kim, Yong-Kil Hong, Sin-Soo Jeun, Sei-Chul Yoon
Radiat Oncol J. 2011;29(3):147-155.   Published online September 30, 2011
Purpose

This study was designed to determine the influencing factors and clinical course of pathologically proven cases of radiation-induced brain injury (RIBI).

Materials and Methods

The pathologic records of twelve patients were reviewed; these patients underwent surgery following radiotherapy due to disease progression found by follow-up imaging. However, they were finally diagnosed with RIBI. All patients had been treated with 3-dimensional conventional fractionated...

Radiotherapy for pituitary adenomas: long-term outcome and complications
Chai Hong Rim, Dae Sik Yang, Young Je Park, Won Sup Yoon, Jung Ae Lee, Chul Yong Kim
Radiat Oncol J. 2011;29(3):156-163.   Published online September 30, 2011
Purpose

To evaluate long-term local control rate and toxicity in patients treated with external beam radiotherapy (EBRT) for pituitary adenomas.

Materials and Methods

We retrospectively reviewed the medical records of 60 patients treated with EBRT for pituitary adenoma at Korea University Medical Center from 1996 and 2006. Thirty-five patients had hormone secreting tumors, 25 patients had non-secreting tumors. Fifty-seven patients had received postoperative...

Co-authorship patterns and networks of Korean radiation oncologists
Jinhyun Choi, Jin Oh Kang, Seo Hyun Park, Sang Ki Kim
Radiat Oncol J. 2011;29(3):164-173.   Published online September 30, 2011
Purpose

This research aimed to analyze the patterns of co-authorship network among the Korean radiation oncologists and to identify attributing factors for the formation of networks.

Materials and Methods

A total of 1,447 articles including contents of 'Radiation Oncology' and 'Therapeutic Radiology' were searched from the KoreaMed database. The co-authorship was assorted by the author's full name, affiliation and specialties. UCINET 6.0 was...

Treatment outcome of nasal natural killer/T-cell lymphoma
Hyun Jin Lee, Sang-Wook Lee, Cheolwon Suh, Jooryung Huh, Sang Min Yoon, Young Seok Kim, Su San Kim, Jong Hoon Kim, Eun Kyung Choi, Seung Do Ahn
Radiat Oncol J. 2011;29(3):174-180.   Published online September 30, 2011
Purpose

To evaluate the radiotherapy treatment outcome of patients in stage IE and IIE nasal natural killer/T-cell lymphoma.

Materials and Methods

From August 1999 to August 2009, 46 patients with stage IE and IIE nasal natural killer/T-cell lymphoma were treated by definitive radiotherapy and chemotherapy. 33 patients were treated with chemotherapy followed by radiotherapy (CT + RT) and they received 50.4 Gy in...

Factors predicting radiation pneumonitis in locally advanced non-small cell lung cancer
Myungsoo Kim, Jihae Lee, Boram Ha, Rena Lee, Kyung-Ja Lee, Hyun Suk Suh
Radiat Oncol J. 2011;29(3):181-190.   Published online September 30, 2011
Purpose

Thoracic radiotherapy is a major treatment modality of stage III non-small cell lung cancer. The normal lung tissue is sensitive to radiation and radiation pneumonitis is the most important dose-limiting complication of thoracic radiation therapy. This study was performed to identify the clinical and dosimetric parameters related to the risk of radiation pneumonitis after definitive radiotherapy in stage III non-small...

The role of squamous cell carcinoma antigen as a prognostic and predictive factor in carcinoma of uterine cervix
Bae Kwon Jeong, Doo Ho Choi, Seung Jae Huh, Won Park, Duk Soo Bae, Byoung-Gie Kim
Radiat Oncol J. 2011;29(3):191-198.   Published online September 30, 2011
Purpose

Although the role of squamous cell carcinoma antigen (SCC-Ag) as a predictive and prognostic factor for uterine cervical cancer has been identified in previous studies, 1) the effective patient group of screening for recurrence with SCC-Ag, 2) the relationship between SCC-Ag and recurrence site, and 3) the relationship between the change of SCC-Ag and treatment outcome or recurrence have not...

Physics Contribution
A comparison of preplan MRI and preplan CT-based prostate volume with intraoperative ultrasound-based prostate volume in real-time permanent brachytherapy
Hyeli Park, Ja Young Kim, Bo Mi Lee, Sei Kyung Chang, Seung Young Ko, Sung Jun Kim, Dong Soo Park, Hyun Soo Shin
Radiat Oncol J. 2011;29(3):199-205.   Published online September 30, 2011
Purpose

The present study compared the difference between intraoperative transrectal ultrasound (iTRUS)-based prostate volume and preplan computed tomography (CT), preplan magnetic resonance imaging (MRI)-based prostate volume to estimate the number of seeds needed for appropriate dose coverage in permanent brachytherapy for prostate cancer.

Materials and Methods

Between March 2007 and March 2011, among 112 patients who underwent permanent brachytherapy with 125I, 60 image...

Analysis of changes in dose distribution due to respiration during IMRT
Jung Suk Shin, Eunhyuk Shin, Youngyih Han, Sang-Gyu Ju, Jin Sung Kim, Sung Hwan Ahn, Tae Gyu Kim, Bae Kwon Jeong, Hee-Chul Park, Young-Chan Ahn, Doo Ho Choi
Radiat Oncol J. 2011;29(3):206-213.   Published online September 30, 2011
Purpose

Intensity modulated radiation therapy (IMRT) is a high precision therapy technique that can achieve a conformal dose distribution on a given target. However, organ motion induced by respiration can result in significant dosimetric error. Therefore, this study explores the dosimetric error that result from various patterns of respiration.

Materials and Methods

Experiments were designed to deliver a treatment plan made for a...

Case Report
Variable uterine uptake of FDG in adenomyosis during concurrent chemoradiation therapy for cervical cancer
Jeong Il Yu, Seung Jae Huh, Young Il Kim, Tae-Joong Kim, Byung Kwan Park
Radiat Oncol J. 2011;29(3):214-217.   Published online September 30, 2011

To avoid improper tumor volume contouring in radiation therapy (RT) and other invasive procedures, we report a case of uterine adenomyosis showing increased 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET)/computed tomography (CT) mimicking malignant tumor in a 44-year-old woman during concurrent chemoradiation therapy (CCRT) for uterine cervical cancer. The adenomyosis was not associated with her menstrual cycle or with...

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