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Table of Contents | December, 2012  Vol. 30  No.4 Previous Issue | Next Issue | Archive
In this issue:


Original Articles
Clinical Investigation
Role of radiotherapy in local control of non-AIDS associated Kaposi's sarcoma patients in Korea: a single institution experience
Ji Hyun Chang, Il Han Kim
Radiat Oncol J. 2012;30(4):153-157.   Published online December 31, 2012
Purpose

There has been no definite consensus on standard treatment, either local or systemic, for the Kaposi's sarcoma (KS). Radiotherapy (RT) can be a good local therapeutic choice especially in non-AIDS associated KS (NAKS) for its indolent behavior.

Materials and Methods

Medical records of 17 KS patients treated with RT at the Seoul National University Hospital from February 1998 to January 2012 were...

Postoperative radiotherapy for ependymoma
Jinhong Jung, Wonsik Choi, Seung Do Ahn, Jin Hong Park, Su Ssan Kim, Young Seok Kim, Sang Min Yoon, Si Yeol Song, Sang-Wook Lee, Jong Hoon Kim, Eun Kyung Choi
Radiat Oncol J. 2012;30(4):158-164.   Published online December 31, 2012
Purpose

To evaluated the patterns of failure, survival rate, treatment-related toxicity and prognostic factors in postoperative radiotherapy of patients with ependymoma.

Materials and Methods

Thirty patients who underwent surgery and postoperative radiotherapy for ependymoma between the period of June 1994 and June 2008 were reviewed retrospectively. The age of patients ranged from 21 months to 66 years (median, 19 years). Seventeen patients had...

Total lymphoid irradiation based conditioning for hematopoietic stem cell transplantation in severe aplastic anemia
Yun-Hee Lee, Ji-Yoon Kim, Byung-Ock Choi, Mi-Ryeong Ryu, Su-Mi Chung
Radiat Oncol J. 2012;30(4):165-172.   Published online December 31, 2012
Purpose

To retrospectively evaluate the outcome and toxicity of total lymphoid irradiation (TLI) based conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in severe aplastic anemia (SAA) patients who experienced an engraftment failure from prior HSCT or were heavily transfused.

Materials and Methods

Between 1995 and 2006, 20 SAA patients received TLI for conditioning of HSCT. All patients were multi-transfused or had...

Prognostic value of 18F-fluorodeoxyglucose positron emission tomography, computed tomography and magnetic resonance imaging in oral cavity squamous cell carcinoma with pathologically positive neck lymph node
Eunjin Jwa, Sang-Wook Lee, Jae-Seung Kim, Jin Hong Park, Su Ssan Kim, Young Seok Kim, Sang Min Yoon, Si Yeol Song, Jong Hoon Kim, Eun Kyung Choi, Seung Do Ahn
Radiat Oncol J. 2012;30(4):173-181.   Published online December 31, 2012
Purpose

To evaluate the prognostic value of preoperative neck lymph node (LN) assessment with 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET), computed tomography (CT), and magnetic resonance imaging (MRI) in oral cavity squamous cell carcinoma (OSCC) patients with pathologically positive LN.

Materials and Methods

In total, 47 OSCC patients with pathologically positive LN were retrospectively reviewed with preoperative 18F-FDG PET and CT/MRI. All patients...

Re-irradiation of recurrent esophageal cancer after primary definitive radiotherapy
Young Suk Kim, Chang Geol Lee, Kyung Hwan Kim, Taehyung Kim, Joohwan Lee, Yona Cho, Woong Sub Koom
Radiat Oncol J. 2012;30(4):182-188.   Published online December 31, 2012
Purpose

For recurrent esophageal cancer after primary definitive radiotherapy, no general treatment guidelines are available. We evaluated the toxicities and clinical outcomes of re-irradiation (re-RT) for recurrent esophageal cancer.

Materials and Methods

We analyzed 10 patients with recurrent esophageal cancer treated with re-RT after primary definitive radiotherapy. The median time interval between primary radiotherapy and re-RT was 15.6 months (range, 4.8 to 36.4...

Changes of the liver volume and the Child-Pugh score after high dose hypofractionated radiotherapy in patients with small hepatocellular carcinoma
Young Il Kim, Hee Chul Park, Do Hoon Lim, Hyo Jung Park, Sang Won Kang, Su Yeon Park, Jin Sung Kim, Youngyih Han, Seung Woon Paik
Radiat Oncol J. 2012;30(4):189-196.   Published online December 31, 2012
Purpose

To investigate the safety of high dose hypofractionated radiotherapy (RT) in patients with small hepatocellular carcinoma (HCC) in terms of liver volumetric changes and clinical liver function.

Materials and Methods

We retrospectively reviewed 16 patients with small HCC who were treated with high dose hypofractionated RT between 2006 and 2009. The serial changes of the liver volumetric parameter were analyzed from pre-RT...

Molecular biomarkers in extrahepatic bile duct cancer patients undergoing chemoradiotherapy for gross residual disease after surgery
Hyeon Kang Koh, Hae Jin Park, Kyubo Kim, Eui Kyu Chie, Hye Sook Min, Sung W. Ha
Radiat Oncol J. 2012;30(4):197-204.   Published online December 31, 2012
Purpose

To analyze the outcomes of chemoradiotherapy for extrahepatic bile duct (EHBD) cancer patients who underwent R2 resection or bypass surgery and to identify prognostic factors affecting clinical outcomes, especially in terms of molecular biomarkers.

Materials and Methods

Medical records of 21 patients with EHBD cancer who underwent R2 resection or bypass surgery followed by chemoradiotherapy from May 2001 to June 2010 were...

The role of postoperative pelvic radiation in stage IV rectal cancer after resection of primary tumor
Joo Hwan Lee, In Young Jo, Jong Hoon Lee, Sei Chul Yoon, Yeon-Sil Kim, Byung Ock Choi, Jun-Gi Kim, Seong Taek Oh, Myeong A Lee, Hong-Seok Jang
Radiat Oncol J. 2012;30(4):205-212.   Published online December 31, 2012
Purpose

To evaluate the effect of pelvic radiotherapy (RT) in patients with stage IV rectal cancer treated with resection of primary tumor with or without metastasectomy.

Materials and Methods

Medical records of 112 patients with stage IV rectal cancer treated with resection of primary tumor between 1990 and 2011 were retrospectively reviewed. Fifty-nine patients received synchronous or staged metastasectomy whereas fifty-three patients did...

Postoperative chemoradiotherapy in high risk locally advanced gastric cancer
Sanghyuk Song, Eui Kyu Chie, Kyubo Kim, Hyuk-Joon Lee, Han-Kwang Yang, Sae-Won Han, Do-Youn Oh, Seock-Ah Im, Yung-Jue Bang, Sung W. Ha
Radiat Oncol J. 2012;30(4):213-217.   Published online December 31, 2012
Purpose

To evaluate treatment outcome of patients with high risk locally advanced gastric cancer after postoperative chemoradiotherapy.

Materials and Methods

Between May 2003 and May 2012, thirteen patients who underwent postoperative chemoradiotherapy for gastric cancer with resection margin involvement or adjacent structure invasion were retrospectively analyzed. Concurrent chemotherapy was administered in 10 patients. Median dose of radiation was 50.4 Gy (range, 45 to...

Prognostic implications of tumor volume response and COX-2 expression change during radiotherapy in cervical cancer patients
Jae Myoung Noh, Won Park, Seung Jae Huh, Eun Yoon Cho, Yoon-La Choi, Duk Soo Bae, Byoung-Gie Kim
Radiat Oncol J. 2012;30(4):218-225.   Published online December 31, 2012
Purpose

The relationship between treatment outcomes, alteration of the expression of biological markers, and tumor volume response during radiotherapy (RT) in patients with uterine cervical cancer was analyzed.

Materials and Methods

Twenty patients with cervical squamous cell carcinoma received definitive RT with (n = 17) or without (n = 3) concurrent chemotherapy. Tumor volumes were measured by three serial magnetic resonance imaging scans...

Letter to the Editor
Troglitazone and tumor inhibition: an evolving concept in the management of systemic malignancies
Shailendra Kapoor
Radiat Oncol J. 2012;30(4):226-227.   Published online December 31, 2012
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