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- Review Article
- Intensity-modulated radiation therapy: a review with a physics perspective
- Byungchul Cho
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Radiat Oncol J. 2018;36(1):1-10. Published online March 30, 2018
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Intensity-modulated radiation therapy (IMRT) has been considered the most successful development in radiation oncology since the introduction of computed tomography into treatment planning that enabled three-dimensional conformal radiotherapy in 1980s. More than three decades have passed since the concept of inverse planning was first introduced in 1982, and IMRT has become the most important and common modality in radiation therapy.... |
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- Original Articles
- Interobserver variation in target volume for salvage radiotherapy in recurrent prostate cancer patients after radical prostatectomy using CT versus combined CT and MRI: a multicenter study (KROG 13-11)
- Eonju Lee, Won Park, Sung Hwan Ahn, Jae Ho Cho, Jin Hee Kim, Kwan Ho Cho, Young Min Choi, Jae-Sung Kim, Jin Ho Kim, Hong-Seok Jang, Young-Seok Kim, Taek-Keun Nam
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Radiat Oncol J. 2018;36(1):11-16. Published online December 15, 2017
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Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI).
Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with... |
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- Preoperative short course radiotherapy with concurrent and consolidation chemotherapies followed by delayed surgery in locally advanced rectal cancer: preliminary results
- Mahdi Aghili
 , Sarvazad Sotoudeh, Reza Ghalehtaki, Mohammad Babaei, Borna Farazmand, Mohammad-Sadegh Fazeli, Amir Keshvari, Peiman Haddad, Farshid Farhan
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Radiat Oncol J. 2018;36(1):17-24. Published online March 30, 2018
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Purpose: This study aimed to assess complications and outcomes of a new approach, that is, combining short course radiotherapy (SRT), concurrent and consolidative chemotherapies, and delayed surgery.
Materials and Methods: In this single arm phase II prospective clinical trial, patients with T3-4 or N+ M0 rectal adenocarcinoma were enrolled. Patients who received induction chemotherapy or previous pelvic radiotherapy were excluded. Study... |
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- Initial clinical outcomes of proton beam radiotherapy for hepatocellular carcinoma
- Jeong Il Yu, Gyu Sang Yoo, Sungkoo Cho, Sang Hoon Jung, Youngyih Han, Seyjoon Park, Boram Lee, Wonseok Kang, Dong Hyun Sinn, Yong-Han Paik, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Hee Chul Park
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Radiat Oncol J. 2018;36(1):25-34. Published online March 29, 2018
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Purpose: This study aimed to evaluate the initial outcomes of proton beam therapy (PBT) for hepatocellular carcinoma (HCC) in terms of tumor response and safety.
Materials and Methods: HCC patients who were not indicated for standard curative local modalities and who were treated with PBT at Samsung Medical Center from January 2016 to February 2017 were enrolled. Toxicity was scored using... |
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- Impact of radiation dose on concurrent chemoradiotherapy for limited-stage small-cell lung cancer
- Junhee Park, Min Kyu Kang
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Radiat Oncol J. 2018;36(1):35-44. Published online March 30, 2018
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Purpose: To evaluate clinical outcomes according to radiation dose in patients with limited-stage small-cell lung cancer (LS-SCLC) treated with concurrent chemoradiotherapy (CCRT).
Materials and Methods: From January 2006 to December 2015, 38 patients with LS-SCLC were treated with CCRT with etoposide and cisplatin. Total radiation doses ranged from 45 Gy to 66 Gy (1.8–2 Gy/fraction) and were classified into three groups:... |
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- Prognostic significance of adjuvant radiation therapy in adenocarcinoma of the cecum
- Sare Hosseini, Ali Mohammad Bananzadeh, Mohammad Mohammadianpanah, Roham Salek, Ali Taghizadeh-Kermani
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Radiat Oncol J. 2018;36(1):45-53. Published online March 5, 2018
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Purpose: Local recurrence is a common failure pattern in adenocarcinoma of the cecum. This study aimed to investigate the potential role of adjuvant radiation therapy on oncologic outcomes of patients with adenocarcinoma of the cecum.
Materials and Methods: This retrospective study was carried out at three large tertiary university hospitals. We analyzed the characteristics, prognostic factors, and survival of 162 patients... |
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- Set-up errors in head and neck cancer treated with IMRT technique assessed by cone-beam computed tomography: a feasible protocol
- Durim Delishaj
 , Stefano Ursino, Francesco Pasqualetti, Fabrizio Matteucci, Agostino Cristaudo, Carlo Pietro Soatti, Amelia Barcellini, Fabiola Paiar
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Radiat Oncol J. 2018;36(1):54-62. Published online March 30, 2018
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Purpose: To investigate set-up errors, suggest the adequate planning target volume (PTV) margin and image-guided radiotherapy frequency in head and neck (H&N) cancer treated with intensity-modulated radiotherapy (IMRT) assessed by kV cone-beam computed tomography (CBCT).
Methods: We analyzed 360 CBCTs in 60 patients with H&N cancer treated with IMRT. The target delineation was contoured according to ICRU62. PTVs were generated by... |
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- Dosimetric comparison of IMRT versus 3DCRT for post-mastectomy chest wall irradiation
- Kartick Rastogi
 , Shantanu Sharma, Shivani Gupta, Nikesh Agarwal, Sandeep Bhaskar, Sandeep Jain
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Radiat Oncol J. 2018;36(1):71-78. Published online March 30, 2018
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Purpose: To compare the dose distribution of three-dimensional conformal radiation therapy (3DCRT) with intensity-modulated radiation therapy (IMRT) for post-mastectomy radiotherapy (PMRT) to left chest wall.
Materials and Methods: One hundred and seven patients were randomised for PMRT in 3DCRT group (n = 64) and IMRT group (n = 43). All patients received 50 Gy in 25 fractions. Planning target volume (PTV)... |
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, Tabitha Pham
