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Table of Contents | September, 2019  Vol. 37  No.3 Previous Issue | Next Issue | Archive
In this issue:


Review Article
Local ablative radiotherapy for oligometastatic non-small cell lung cancer
Yang-Gun Suh, Jaeho Cho
Radiat Oncol J. 2019;37(3):149-155.   Published online September 30, 2019
In metastatic non-small cell lung cancer (NSCLC), the role of radiotherapy (RT) has been limited to palliation to alleviate the symptoms. However, with the development of advanced RT techniques, recent advances in immuno-oncology therapy targeting programmed death 1 (PD-1) and programmed death ligand 1 (PD-L1) and targeted agents for epidermal growth factor receptor (EGFR) mutation or anaplastic lymphoma kinase (ALK)...
Original Articles
Clinical Investigations
The value of prophylactic cranial irradiation in limited-stage small cell lung cancer: should it always be recommended?
Minji Koh, Si Yeol Song, Ji Hwan Jo, Geumju Park, Jae Won Park, Su Ssan Kim, Eun Kyung Choi
Radiat Oncol J. 2019;37(3):156-165.   Published online September 30, 2019

Purpose: Prophylactic cranial irradiation (PCI) is a standard treatment for limited-stage small cell lung cancer (LS-SCLC) showing a response to initial treatment, but many patients do not receive PCI due to comorbidities or refusal. This study aims to define the patient group for whom PCI can be omitted with minimal risk. Materials and Methods: Patients with LS-SCLC who underwent radiotherapy with...
Prognostic value of neutrophil-to-lymphocyte ratio in locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
Eun Young Park, Yeon-Sil Kim, Kyu Hye Choi, Jin Ho Song, Hyo Chun Lee, Sook-Hee Hong, Jin-Hyoung Kang
Radiat Oncol J. 2019;37(3):166-175.   Published online September 30, 2019

Purpose: This study aimed to investigate neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors in patients with locally advanced non-small cell lung cancer (NSCLC) who received concurrent chemoradiotherapy (CCRT). Materials and Methods: We retrospectively analyzed 66 patients with locally advanced NSCLC treated with definitive CCRT. Among these patients, 95% received paclitaxel/carboplatin or docetaxel/cisplatin. The median radiation dose was 66...
Chemoradiotherapy versus radiotherapy alone following induction chemotherapy for elderly patients with stage III lung cancer
Dong-Yun Kim, Changhoon Song, Se Hyun Kim, Yu Jung Kim, Jong Seok Lee, Jae-Sung Kim
Radiat Oncol J. 2019;37(3):176-184.   Published online September 30, 2019

Purpose: It is unclear whether adding concurrent chemotherapy (CT) to definitive radiotherapy (RT) following induction CT is a tolerable and cost effective treatment for non-small-cell lung cancer (NSCLC) patients aged 70 years or older with comorbidities. This study evaluated the actual clinical outcomes between concurrent chemoradiotherapy (CCRT) and RT alone following induction CT or not in patients (≥70 years) in...
Higher thoracic radiation dose is beneficial in patients with extensive small cell lung cancer
Han Gyul Yoon, Jae Myoung Noh, Yong Chan Ahn, Dongryul Oh, Hongryull Pyo, Haeyoung Kim
Radiat Oncol J. 2019;37(3):185-192.   Published online September 30, 2019

Purpose: The effectiveness of thoracic radiation therapy (TRT) in extensive-stage small cell lung cancer (ES-SCLC) patients is increasingly reported, but there is no definite consensus on its application. The aim of this study was to identify factors associated with better outcomes of TRT among patients with ES-SCLC, focusing on whether a higher TRT dose could improve treatment outcome. Materials and Methods:...
The role of salvage radiotherapy in recurrent thymoma
Andrew Jihoon Yang, Seo Hee Choi, Hwa Kyung Byun, Hyun Ju Kim, Chang Geol Lee, Jaeho Cho
Radiat Oncol J. 2019;37(3):193-200.   Published online September 30, 2019

Purpose: To explore the role of salvage radiotherapy (RT) for recurrent thymoma as an alternative to surgery. Materials and Methods: Between 2007 and 2015, 47 patients who received salvage RT for recurrent thymoma at Yonsei Cancer Center were included in this study. Recurrent sites included initial tumor bed (n = 4), pleura (n = 19), lung parenchyma (n = 10), distant...
An effective patient training for deep inspiration breath hold technique of left-sided breast on computed tomography simulation procedure at King Chulalongkorn Memorial Hospital
Puntiwa Oonsiri, Metinee Wisetrinthong, Manatchanok Chitnok, Kitwadee Saksornchai, Sivalee Suriyapee
Radiat Oncol J. 2019;37(3):201-206.   Published online September 30, 2019

Purpose: To observe the effectiveness of the practical instruction sheet and the educational video for left-sided breast treatment in a patient receiving deep inspiration breath hold (DIBH) technique. Two parameters, simulation time and patient satisfaction, were assessed through the questionnaire. Methods: Two different approaches, which were the instruction sheet and educational video, were combinedly used to assist patients during DIBH procedures....
Prognostic factors in hepatocellular carcinoma patients with bone metastases
Sungmin Kim, Youngmin Choi, Dong-Won Kwak, Hyung Sik Lee, Won-Joo Hur, Yang Hyun Baek, Sung Wook Lee
Radiat Oncol J. 2019;37(3):207-214.   Published online September 30, 2019

Purpose: To identify the prognostic factors that could influence survival and to compare prognoses of the patients with the number of the risk factors that might assist in the adequate management of hepatocellular carcinoma (HCC) patients with bone metastases that showed a heterogeneous range of survival. Materials and Methods: A total of 41 patients, treated with radiotherapy (RT) for bone metastases...
Prognostic significance of lymphovascular invasion in patients with prostate cancer treated with postoperative radiotherapy
Jae-Uk Jeong, Taek-Keun Nam, Ju-Young Song, Mee Sun Yoon, Sung-Ja Ahn, Woong-Ki Chung, Ick Joon Cho, Yong-Hyub Kim, Shin Haeng Cho, Seung Il Jung, Dong Deuk Kwon
Radiat Oncol J. 2019;37(3):215-223.   Published online September 30, 2019

Purpose: To determine prognostic significance of lymphovascular invasion (LVI) in prostate cancer patients who underwent adjuvant or salvage postoperative radiotherapy (PORT) after radical prostatectomy (RP) Materials and Methods: A total of 168 patients with prostate cancer received PORT after RP, with a follow-up of ≥12 months. Biochemical failure after PORT was defined as prostate-specific antigen (PSA) ≥0.2 ng/mL after PORT or...
Patterns of recurrence after radiation therapy for high-risk neuroblastoma
Ji Hwan Jo, Seung Do Ahn, Minji Koh, Jong Hoon Kim, Sang-wook Lee, Si Yeol Song, Sang Min Yoon, Young Seok Kim, Su Ssan Kim, Jin-hong Park, Jinhong Jung, Eun Kyung Choi
Radiat Oncol J. 2019;37(3):224-231.   Published online September 30, 2019

Purpose: To investigate the patterns of recurrence in patients with neuroblastoma treated with radiation therapy to the primary tumor site. Materials and Methods: We retrospectively analyzed patients with high-risk neuroblastoma managed with definitive treatment with radiation therapy to the primary tumor site between January 2003 and June 2017. These patients underwent three-dimensional conformal radiation therapy or intensity-modulated radiation therapy. A total...
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