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- Review Article
- Local ablative radiotherapy for oligometastatic non-small cell lung cancer
- Yang-Gun Suh
, Jaeho Cho
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Radiat Oncol J. 2019;37(3):149-155. Published online September 30, 2019
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In metastatic non-small cell lung cancer (NSCLC), the role of radiotherapy (RT) has been limited to palliation to alleviate the symptoms. However, with the development of advanced RT techniques, recent advances in immuno-oncology therapy targeting programmed death 1 (PD-1) and programmed death ligand 1 (PD-L1) and targeted agents for epidermal growth factor receptor (EGFR) mutation or anaplastic lymphoma kinase (ALK)... |
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- Original Articles
- Clinical Investigations
- The value of prophylactic cranial irradiation in limited-stage small cell lung cancer: should it always be recommended?
- Minji Koh
, Si Yeol Song , Ji Hwan Jo , Geumju Park , Jae Won Park , Su Ssan Kim , Eun Kyung Choi
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Radiat Oncol J. 2019;37(3):156-165. Published online September 30, 2019
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Purpose: Prophylactic cranial irradiation (PCI) is a standard treatment for limited-stage small cell lung cancer (LS-SCLC) showing a response to initial treatment, but many patients do not receive PCI due to comorbidities or refusal. This study aims to define the patient group for whom PCI can be omitted with minimal risk.
Materials and Methods: Patients with LS-SCLC who underwent radiotherapy with... |
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- Prognostic value of neutrophil-to-lymphocyte ratio in locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
- Eun Young Park
, Yeon-Sil Kim , Kyu Hye Choi , Jin Ho Song , Hyo Chun Lee , Sook-Hee Hong , Jin-Hyoung Kang
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Radiat Oncol J. 2019;37(3):166-175. Published online September 30, 2019
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Purpose: This study aimed to investigate neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors in patients with locally advanced non-small cell lung cancer (NSCLC) who received concurrent chemoradiotherapy (CCRT).
Materials and Methods: We retrospectively analyzed 66 patients with locally advanced NSCLC treated with definitive CCRT. Among these patients, 95% received paclitaxel/carboplatin or docetaxel/cisplatin. The median radiation dose was 66... |
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- Chemoradiotherapy versus radiotherapy alone following induction chemotherapy for elderly patients with stage III lung cancer
- Dong-Yun Kim
, Changhoon Song , Se Hyun Kim , Yu Jung Kim , Jong Seok Lee , Jae-Sung Kim
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Radiat Oncol J. 2019;37(3):176-184. Published online September 30, 2019
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Purpose: It is unclear whether adding concurrent chemotherapy (CT) to definitive radiotherapy (RT) following induction CT is a tolerable and cost effective treatment for non-small-cell lung cancer (NSCLC) patients aged 70 years or older with comorbidities. This study evaluated the actual clinical outcomes between concurrent chemoradiotherapy (CCRT) and RT alone following induction CT or not in patients (≥70 years) in... |
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- Higher thoracic radiation dose is beneficial in patients with extensive small cell lung cancer
- Han Gyul Yoon
, Jae Myoung Noh , Yong Chan Ahn , Dongryul Oh , Hongryull Pyo , Haeyoung Kim
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Radiat Oncol J. 2019;37(3):185-192. Published online September 30, 2019
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Purpose: The effectiveness of thoracic radiation therapy (TRT) in extensive-stage small cell lung cancer (ES-SCLC) patients is increasingly reported, but there is no definite consensus on its application. The aim of this study was to identify factors associated with better outcomes of TRT among patients with ES-SCLC, focusing on whether a higher TRT dose could improve treatment outcome.
Materials and Methods:... |
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- The role of salvage radiotherapy in recurrent thymoma
- Andrew Jihoon Yang
, Seo Hee Choi , Hwa Kyung Byun , Hyun Ju Kim , Chang Geol Lee , Jaeho Cho
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Radiat Oncol J. 2019;37(3):193-200. Published online September 30, 2019
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Purpose: To explore the role of salvage radiotherapy (RT) for recurrent thymoma as an alternative to surgery.
Materials and Methods: Between 2007 and 2015, 47 patients who received salvage RT for recurrent thymoma at Yonsei Cancer Center were included in this study. Recurrent sites included initial tumor bed (n = 4), pleura (n = 19), lung parenchyma (n = 10), distant... |
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- Prognostic factors in hepatocellular carcinoma patients with bone metastases
- Sungmin Kim
, Youngmin Choi , Dong-Won Kwak , Hyung Sik Lee , Won-Joo Hur , Yang Hyun Baek , Sung Wook Lee
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Radiat Oncol J. 2019;37(3):207-214. Published online September 30, 2019
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Purpose: To identify the prognostic factors that could influence survival and to compare prognoses of the patients with the number of the risk factors that might assist in the adequate management of hepatocellular carcinoma (HCC) patients with bone metastases that showed a heterogeneous range of survival.
Materials and Methods: A total of 41 patients, treated with radiotherapy (RT) for bone metastases... |
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- Prognostic significance of lymphovascular invasion in patients with prostate cancer treated with postoperative radiotherapy
- Jae-Uk Jeong
, Taek-Keun Nam , Ju-Young Song , Mee Sun Yoon , Sung-Ja Ahn , Woong-Ki Chung , Ick Joon Cho , Yong-Hyub Kim , Shin Haeng Cho , Seung Il Jung , Dong Deuk Kwon
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Radiat Oncol J. 2019;37(3):215-223. Published online September 30, 2019
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Purpose: To determine prognostic significance of lymphovascular invasion (LVI) in prostate cancer patients who underwent adjuvant or salvage postoperative radiotherapy (PORT) after radical prostatectomy (RP)
Materials and Methods: A total of 168 patients with prostate cancer received PORT after RP, with a follow-up of ≥12 months. Biochemical failure after PORT was defined as prostate-specific antigen (PSA) ≥0.2 ng/mL after PORT or... |
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- Patterns of recurrence after radiation therapy for high-risk neuroblastoma
- Ji Hwan Jo
, Seung Do Ahn , Minji Koh , Jong Hoon Kim , Sang-wook Lee , Si Yeol Song , Sang Min Yoon , Young Seok Kim , Su Ssan Kim , Jin-hong Park , Jinhong Jung , Eun Kyung Choi
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Radiat Oncol J. 2019;37(3):224-231. Published online September 30, 2019
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Purpose: To investigate the patterns of recurrence in patients with neuroblastoma treated with radiation therapy to the primary tumor site.
Materials and Methods: We retrospectively analyzed patients with high-risk neuroblastoma managed with definitive treatment with radiation therapy to the primary tumor site between January 2003 and June 2017. These patients underwent three-dimensional conformal radiation therapy or intensity-modulated radiation therapy. A total... |
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