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Table of Contents | June, 2020  Vol. 38  No.2 Previous Issue | Next Issue | Archive
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Review Articles
The effect of radiotherapy on rectal cancer: a histopathological appraisal and prognostic indicators
Mohammad AlQudah, Emil Salmo, Najib Haboubi
Radiat Oncol J. 2020;38(2):77-83.   Published online June 16, 2020
The management of rectal cancer is a major undertaking. There are currently multiple treatment modalities with variable degrees of complications. Radiotherapy (RT) is one of the more frequently used modalities either on its own or more frequently with chemotherapy mostly before the definitive surgery. The outcome of RT is unpredictable. RT has its serious side effects and there are no...
Late side effects of radiation treatment for head and neck cancer
Itzhak Brook
Radiat Oncol J. 2020;38(2):84-92.   Published online June 25, 2020
Patients undergoing radiation therapy for head and neck cancer (HNC) experience significant early and long-term side effects. The likelihood and severity of complications depends on a number of factors, including the total dose of radiation delivered, over what time it was delivered and what parts of the head and neck received radiation. Late side effects include: permanent loss of saliva;...
Original Articles
Clinical Investigation
Running of high patient volume radiation oncology department during COVID-19 crisis in India: our institutional strategy
Manoj Gupta, Rachit Ahuja, Sweety Gupta, Deepa Joseph, Rajesh Pasricha, Swati Verma, Laxman Pandey
Radiat Oncol J. 2020;38(2):93-98.   Published online June 12, 2020

Purpose: Due to COVID 19 pandemic, the treatment of cancer patients has become a dilemma for every oncologist. Cancer patients are at an increased risk of immunosuppression and have a higher risk to acquire any infection. There are individual experiences from some centers regarding the management of cancer patients during such a crisis. So we have developed our institutional strategy...
Gene signature for prediction of radiosensitivity in human papillomavirus-negative head and neck squamous cell carcinoma
Su Il Kim, Jeong Wook Kang, Joo Kyung Noh, Hae Rim Jung, Young Chan Lee, Jung Woo Lee, Moonkyoo Kong, Young-Gyu Eun
Radiat Oncol J. 2020;38(2):99-108.   Published online June 9, 2020

Purpose: The probability of recurrence of cancer after adjuvant or definitive radiotherapy in patients with human papillomavirus-negative (HPV(–)) head and neck squamous cell carcinoma (HNSCC) varies for each patient. This study aimed to identify and validate radiation sensitivity signature (RSS) of patients with HPV(–) HNSCC to predict the recurrence of cancer after radiotherapy. Materials and Methods: Clonogenic survival assays were performed...
Late-term effects of hypofractionated chest wall and regional nodal radiotherapy with two-dimensional technique in patients with breast cancer
Budhi Singh Yadav, Anshuma Bansal, Philip George Kuttikat, Deepak Das, Ankita Gupta, Divya Dahiya
Radiat Oncol J. 2020;38(2):109-118.   Published online June 4, 2020

Purpose: Hypofractionated radiotherapy (RT) is becoming a new standard in postoperative treatment of patients with early stage breast cancer after breast conservation surgery. However, data on hypofractionation in patients with advanced stage disease who undergo mastectomy followed by local and regional nodal irradiation (RNI) is lacking. In this retrospective study, we report late-term effects of 3 weeks post-mastectomy hypofractionated local...
Short-course versus long-course neoadjuvant chemoradiotherapy in patients with rectal cancer: preliminary results of a randomized controlled trial
Mahdi Aghili, Nastaran Khalili, Neda Khalili, Mohammad Babaei, Farshid Farhan, Peiman Haddad, Samaneh Salarvand, Amir Keshvari, Mohammad Sadegh Fazeli, Negin Mohammadi, Reza Ghalehtaki
Radiat Oncol J. 2020;38(2):119-128.   Published online June 5, 2020

Purpose: Colorectal cancer is becoming an increasing concern in the middle-aged population of Iran. This study aimed to compare the preliminary results of short-course and long-course neoadjuvant chemoradiotherapy treatment for rectal cancer patients. Materials and Methods: Patients in group I received three-dimensional conformational radiotherapy with a dose of 25 Gy/5 fractions in 1 week plus concurrent XELOX regimen (capecitabine 625 mg/m2...
The predictive value of serum myeloma protein in solitary plasmacytoma
Won Ick Chang, Hyeon Kang Koh, Sung-Soo Yoon, Han-Soo Kim, Keun-Yong Eom, Il Han Kim
Radiat Oncol J. 2020;38(2):129-137.   Published online June 18, 2020

Purpose: To identify the clinical usefulness of serum M protein and to establish a rationale for regular follow-up with serum protein electrophoresis in solitary plasmacytoma. Materials and Methods: Sixty-nine patients with solitary plasmacytoma and solitary plasmacytoma with minimal marrow involvement according to the International Myeloma Working Group criteria were retrospectively reviewed. Results: At a median follow-up of 6.2 years, 5-year local...
Physics Contribution
Dosimetric comparison of coplanar and non-coplanar volumetric-modulated arc therapy in head and neck cancer treated with radiotherapy
Sanjib Gayen, Sri Harsha Kombathula, Sumanta Manna, Sonal Varshney, Puneet Pareek
Radiat Oncol J. 2020;38(2):138-147.   Published online May 26, 2020

Purpose: To evaluate the dosimetric variations in patients of head and neck cancer treated with definitive or adjuvant radiotherapy using optimized non-coplanar (ncVMAT) beams with coplanar (cVMAT) beams using volumetric arc therapy. Materials and Methods: Twenty-two patients of head and neck cancer that had received radiotherapy using VMAT in our department were retrospectively analyzed. Each of the patients was planned using...
Case Report
Exceptional response to radiotherapy in unresectable pleuropulmonary blastoma of a child
Jae Sik Kim, Joo Ho Lee
Radiat Oncol J. 2020;38(2):148-150.   Published online June 23, 2020
Pleuropulmonary blastoma (PPB) is a rare intrathoracic neoplasm in children. Although surgery with or without chemotherapy mainly conducted, the response of radiotherapy (RT) has not been evaluated yet. For unresectable tumor, RT might be considered as one option to decrease tumor extent to relieve obstructing symptoms or to facilitate successive treatment. We report one child in whom PPB with DICER1...
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