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Table of Contents | December, 2020  Vol. 38  No.4 Previous Issue | Next Issue | Archive
In this issue:



Review Articles
Erectile dysfunction and cancer: current perspective
Renu Madan, Chinna Babu Dracham, Divya Khosla, Shikha Goyal, Arun Kumar Yadav
Radiat Oncol J. 2020;38(4):217-225.   Published online August 26, 2020
Erectile dysfunction (ED) is one of the major but underreported concerns in cancer patients and survivors. It can lead to depression, lack of intimacy between the couple, and impaired quality of life. The causes of erectile dysfunction are psychological distress and endocrinal dysfunction caused by cancer itself or side effect of anticancer treatment like surgery, radiotherapy, chemotherapy and hormonal therapy....
Harnessing genome-wide association studies to minimize adverse radiation-induced side effects
Cecil M. Benitez, Susan J. Knox
Radiat Oncol J. 2020;38(4):226-235.   Published online November 25, 2020
Radiotherapy is used as definitive treatment in approximately two-thirds of all cancers. However, like any treatment, radiation has significant acute and long-term side effects including secondary malignancies. Even when similar radiation parameters are used, 5%–10% of patients will experience adverse radiation side effects. Genomic susceptibility is thought to be responsible for approximately 40% of the clinical variability observed. In the...
Original Articles
Clinical Investigation
Post-mastectomy radiation therapy in breast reconstruction: a patterns of care study of the Korean Radiation Oncology Group
Gowoon Yang, Jee Suk Chang, Kyung Hwan Shin, Jin Ho Kim, Won Park, Haeyoung Kim, Kyubo Kim, Ik Jae Lee, Won Sup Yoon, Jihye Cha, Kyu-Chan Lee, Jin Hee Kim, Jin Hwa Choi, Sung-Ja Ahn, Boram Ha, Sun Young Lee, Dong Soo Lee, Jeongshim Lee, Sei One Shin, Yong Bae Kim
Radiat Oncol J. 2020;38(4):236-243.   Published online December 16, 2020

Purpose: The details of breast reconstruction and radiation therapy (RT) vary between institutions; therefore, we sought to investigate the practice patterns of radiation oncologists who specialize in breast cancer. Materials and Methods: We identified the practice patterns and inter-hospital variations from a multi-center cohort of women with breast cancer who underwent post-mastectomy RT (PMRT) to the reconstructed breast at 16 institutions...
Prognostic significance of lymph node ratio after neoadjuvant chemoradiation therapy for esophageal squamous cell carcinoma
Jeong Yun Jang, Jesang Yu, Kye Jin Song, Yoon young Jo, Ye Jin Yoo, Sung-Bae Kim, Sook Ryun Park, Young-Hee Kim, Hyeong Ryul Kim, Jong Hoon Kim
Radiat Oncol J. 2020;38(4):244-252.   Published online November 25, 2020

Purpose: We retrospectively evaluated the prognostic significance of lymph node ratio (LNR) in patients with esophageal squamous cell carcinoma who underwent neoadjuvant concurrent chemoradiation therapy (NCRT) followed by surgery. Materials and Methods: In total, 270 patients who underwent NCRT followed by surgery between August 2005 and December 2015 were included. They were divided into three groups: LNR 0 (n = 196),...
Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy
Debnarayan Dutta, Kaushik Jagannath Kataki, Shibu George, Sruthi K. Reddy, Ajay Sashidharan, Rajesh Kannan, Ram Madhavan, Haridas Nair, Tushar Tatineni, Raghavendra Holla
Radiat Oncol J. 2020;38(4):253-261.   Published online November 30, 2020
Background: Evaluate morbidities and “quality” of fiducial marker placement in primary liver tumours (hepatocellular carcinoma [HCC]) for CyberKnife. Materials and Methods: Thirty-six HCC with portal vein thrombosis(PVT) were evaluated for “quality” of fiducial placement, placement time, pain score, complications, recovery time and factors influencing placement. Results: One hundred eight fiducials were placed in 36 patients. Fiducial placement radiation oncologist score was...
Real world clinical outcomes of adjuvant sequential chemoradiation in patients with gallbladder carcinomas with poor performance status
Rakesh Kapoor, Kannan Periasamy, Rajesh Gupta, Arun Yadav, Divya Khosla
Radiat Oncol J. 2020;38(4):262-269.   Published online December 28, 2020
Purpose The purpose of the study is to analyze the overall survival, relapse-free survival, and relapse patterns of adjuvant sequential chemoradiation for gallbladder cancers after curative resection in patients with poor performance status. Materials and Methods We retrospectively reviewed clinical records of gallbladder patients with pathologic stage T2-4 or node positivity treated with sequential chemoradiation at our institute between January 2015 and January...
Physics Contribution
Dosimetric comparative study of 3DCRT, IMRT, VMAT, Ecomp, and Hybrid techniques for breast radiation therapy
Semaya Natalia Chen, Prabhakar Ramachandran, Pradip Deb
Radiat Oncol J. 2020;38(4):270-281.   Published online December 15, 2020

Purpose: To assess and compare the dosimetric parameters obtained between three-dimensional conformal radiotherapy (3DCRT), three-dimensional field-in-field (3DFIF), 5-field intensity-modulated radiotherapy (IMRT MF5), tangential IMRT (tIMRT), tangential volumetric modulated arc therapy (tVMAT), electronic tissue compensation (Ecomp), and Hybrid treatment plans. Material and Methods: Thirty planning computed tomography datasets obtained from patients previously treated with whole breast radiation therapy (WBRT) were utilized...
Case Reports
Primary intracranial leiomyosarcoma presenting with frontal bone mass: a case report
Shaghayegh Kamian, Abdolali Ebrahimi, Kaveh Ebrahim Zadeh, Behnaz Behzadi
Radiat Oncol J. 2020;38(4):282-286.   Published online December 2, 2020
Primary intracranial mesenchymal neoplasms are rare tumors. These tumors are usually metastatic disease from other primary sites. We presented a 31-year-old man with a 6-month history of gradually enlarging frontal mass and positional headache. There was no other symptom demonstrating other organs’ involvement. The patient underwent an uncomplicated craniotomy with clear surgical margins. The pathology review and the immunohistochemistry staining...
Management of grade 3 acute dermatitis with moist desquamation after adjuvant chest wall radiotherapy: a case report
Durim Delishaj, Romerai D'amico, Daniela Corvi, Giuseppe De Nobili, Alessandro Alghisi, Francesco Colangelo, Alessandra Cocchi, Fausto Declich, Carlo Pietro Soatti
Radiat Oncol J. 2020;38(4):287-290.   Published online December 28, 2020
We reported a successful case management of G3 skin acute dermatitis in a 32-year-old woman affected by locally advanced breast cancer underwent adjuvant chest wall irradiation. Skin acute toxicity with dry desquamation areas was treated daily with dressing medication using physiological solution, oxygen therapy and applying hyaluronic acid gauze. At the end of radiotherapy treatment, G3 skin acute dermatitis with...
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