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Table of Contents | , 1990  Vol. 8  No.2 Previous Issue | Next Issue | Archive
In this issue:

Original Articles
Quantitative Analysis of DNA Single-strand Breaks in EL 4 cells and Mouse Spleen Lymphocytes after Irradiation
Seoun Yul Yoo, Chul Koo Cho, Kyung Hwan Koh, Woo Yoon Park, Young Hwan Park, Sung Ho Kim, Tae Hwan Kim, In Yong Chung
Radiat Oncol J. 1990;8(2):137-144.
The filter elution technique was used to assay Co-60 g ray-induced DNA single-strand breaks (SSB) in EL 4 mouse leukemia cell and spleen lymphocyte. The lymphocytes were stimulated with lipopolysaccharide (LPS, 20 mug/ml) to label [3H] thymidine. EL 4 cells and lymphocytes in suspension were exposed at 0degree C to gy, 1 gy, 5 gy, 10 gy of Co-60 radiation...
Radioprotective Effect of Mesna on Mouse Testis
Samuel Ryu, Jae Cheol Kim, Sang Bo Kim, In Kyu Park
Radiat Oncol J. 1990;8(2):145-150.
Mesna has been used with ifosfamide to prevent urotoxicity in the treatment of testicular cancers. This drug also protected the toxicities of adriamycin without compromising cytostatic activity. With n idea of radioprotective role of sulfhydryl group of radioprotectors and of mesna decreasing the toxic effect of adriamycin which produces free radicals, mesna and radiation were administered to mice to study...
Acute Response to Co-60 Total Body Irradiation (TBI) With 600 cgy at 3 Different Does Rates in the Mice
Cheol Hoon Kang, Sung Kyu Kum, Sei One Shin, Myung Se Kim
Radiat Oncol J. 1990;8(2):151-154.
The acute effects of variable dos rates to total body irradiation (TBI) were investigated with 600 cgy of single exposure in the mice as a preclinical model. Total 80 mice (ICR) were used. Twenty of which served as controls, receiving no irradiation. All irradiated mice showed a universal decline in their weight and white blood cell count. The degree of...
Design and Thermal Distribution of Microwave Spiral Antenna
Kyung Ja Lee
Radiat Oncol J. 1990;8(2):155-162.
Spiral microwave antennas have been developed and measure the thermal distribution in agar phantom. The design has been configured in three types, 3cm f applicator with 24.5cm length (A type), 4cm f with 12.2cm (B type) and 6cm f with 24.5cm length (C type). The relative specific absorption rate (SAR) measured in phantom have been used to estimate the depth...
The Efficacy of Radiation Therapy in the Treatment of Pituitary Adenoma
Heung Lee Cho, Kwang Mo Yang, Seung Chang Shon, Hyun Suk Suh
Radiat Oncol J. 1990;8(2):163-168.
Between 1984 and 1989, 22 patients with pituitary adenomas were treated with radiation therapy. The tumor was controlled in 18 of 22 (81.8%) patients for an observed period of II to 98 months. Eleven of 12 (92%) patients with visual field defect experienced nomalization or improvement, and 3 of 5 evaluable patients with hyperprolactinemia achieved normalization in one and decrement...
Retinoblastoma: Result of Radiotherapy
Il Han Kim, Jong Hoon Kim, Charn Il Park
Radiat Oncol J. 1990;8(2):169-176.
Radiotherapy result was analyzed in 23 children with retinoblastoma treated in Seoul National University Hospital from 1980 to 1987. Three (17%) had bilateral tumor at diagnosis. Among 20 children with unilateral retinoblastoma 13 children got radiotherapy after enucleation, 2 were treated with radiotherapy alone, and 5 were delivered with radiotherapy after relapse. Of 15 non-recurrent unilateral tumors, there were 5...
Analysis of Treatment Result of Nasopharyngeal Cancer
Samuel Ryu, Sang Bo Kim, Jae Cheol Kim, Hong U, In Kyu Park, Jun Sik Park
Radiat Oncol J. 1990;8(2):177-182.
From 1984 to 1988, fourt two patients with nasopharyngeal cancer were treated at the Department of Radiation Oncology in Kyungpook National University Hospital. Thirteen patients refused treatment and the median survival time was 7.8 months. Twenty nine patients received a full course of radiation at least 70 gy to the primary site and 60 gy to the nodal sites. These...
Nasopharyngeal Cancer in Patients Under Thirty Years of Age
Ki Jung Ahn, Eun Ji Chung, Hyung Sik Lee, Sun Rock Moon, Jin Sil Seong, Gwi Eon Kim, Chang Ok Suh, John J Kyu Loh
Radiat Oncol J. 1990;8(2):183-188.
Between January 1971 and December 1987, 113 patients with nasopharyngeal cancer (NPC) were treated by radiation therapy with or without chemotherapy in the department of Radiation Oncology, Yonsei University Hospital. There were 19 patients under thirty years of age. The histology was undifferentiated carcinoma in 68% of the younger patients as compared to 47% of the older patients. Sex, stage,...
Primary Radiotherapy of Oropharyngeal Carcinoma: Experience in Korea Cancer Center Hospital (1980. 1-1986. 12)
Young Hwan Park, Woo Yoon Park, Chul Koo Cho, Kyoung Hwan Koh, Seong Yul Yoo, Yoon Sang Shim, Kyoung Kyun Oh, Yong Sik Lee
Radiat Oncol J. 1990;8(2):189-198.
Sixty-six patients with squamous cell carcinoma of the cropharynx were treated with radiation therapy and retrospectively analyzed to evaluate the treatment result in the Department of Therapeutic Radiology, Korea Cancer Center Hospital between January 1980 and December 1986. There were 42 patients with carcinoma of the tonsil including the fossa and pillar, 9 patients with carcinoma of the base of...
The Heterogeneity of T2NO glottic Carcinoma Treated by Irradiation
Hyung Sik Lee, Sun Rock Moon, Ki Jung Ahn, Eun Ji Chung, Chang Ok Suh, Gwi Eon Kim, John J K Loh
Radiat Oncol J. 1990;8(2):199-206.
During a ten-year period from 1978 through 1987, 44 patients with T2NOMO glottic cancer were treated with radical radiation therapy at the Yonsei University Medical Center. Forty-two patients had a minimum follow-up of 3 years, and 81% had at least five years of follow-up. Patients were staged according to the AJCC system. Forty-two patients have been analyzed in detail with respect...
Correlation Between Response to Induction Chemotherapy and Subsequent Radiotherapy in Previously Untreated Patients with Squamous Cell Carcinomas of the Head and Neck
Woo Yoon Park, Seong Yul Yoo, Kyoung Hwan Koh, Chul Koo Cho, Young Hwan Park, Youn Sang Shim, Kyung Kyoon Oh, Yong Sik Lee
Radiat Oncol J. 1990;8(2):207-212.
To determine the correlation between the response to induction chemotherapy and subsequent radiotherapy we analyzed the clinical records of 60 patients with locally advanced carcinoma of the head and neck retrospectively who had completed a full course (2~3 cycle) of induction chemotherapy and curative radiotherapy in Korea Cancer Center Hospital between 1986 and 1989. Chemotherapy was administered with CDDP+Bleomycin (BP)...
Short-Term Results of Non-Small Cell Lung Cancer with Curative Radiotherapy
Sung Ja Ahn, Seung Jin Park, Woong Ki Chung, Byung Sik Nah
Radiat Oncol J. 1990;8(2):213-218.
A retrospective analysis was performed on 102 patients with non-small cell lung cancer who received the curative radiotherapy from August 1985 to October 1988 at the Department of Therapeutic Radiology of Chonnam University Hospital. The follow-up period was ranged from 1 to 37 months and the median follow-up time was 15 months. The acturial 1 and 2 year survival rate...
Large Cell Carcinoma of the Lung: An analysis of clinical features and survival
Jin Yeong Yang, Hyung Sik Lee, Sun Rock Moon, Gwi Eon Kim, Chang Ok Suh, John J K Loh, Won Yong Oh, In Soon Whang
Radiat Oncol J. 1990;8(2):219-224.
This is a retrospective review of 33 patients with large cell lung carcinoma treated at Yonsei University Cancer Center between Jan. 1985 and Dec. 1989. Of the thirty-three patients, twenty eight were men and five women. Median age was 59 years. Large cell undifferentiated carcinoma was the most common pathologic type, 78.8%. Twenty one of thirty three patients had far...
The result of Radiotherapy in Malignant thymona
Sung Ja Ahn, Charn Il Park
Radiat Oncol J. 1990;8(2):225-230.
Twenty one patients of malignant thymoma treated with curative aim at the Department of Therapeutic Radiology of Seoul National University Hospital from 1979 to 1987 were analysed retrospectively. The 3 year overall and relapse free survival rate was 80.5% and 78.6%, respectively. Myasthenia gravis (Mg) was seen in 43.5% at presentation and disappeared in 40% (4/10) after radiotherapy with or without...
Treatment of Carcino ma of the Uterine Cervix with High-Dose-Rate Intracavitary Irradiation using Ralstron
Chang Ok Suh, Gwi Eon Kim, John J K Loh
Radiat Oncol J. 1990;8(2):231-240.
From May 1979 through December 1981 a total of 524 patients with carcinoma of the uterine cervix were treated by radiation therapy with curative intent. Among the 524 patients, 356 were treated with a high-dose-rate (HDR), remote-controlled, afterloading intracavitary irradiation (ICR) system using a cobalt source (Ralstron), and 168 patients received a low-dose-rate (LER) ICR using a radium source. External...
Analysis of Radiotherapy Associated Factors in Stage IIb Carcinoma of Uterine Cervix
Chang Woo Moon, Tae Sig Jeung, Ha Yong Yum
Radiat Oncol J. 1990;8(2):241-254.
331 patients of stage IIb uterine cervix cancer treated by radiation alone at Kosin Medical Center between June 1980 and Dec. 1985 were analysed to determine parameters of radiotherapy associated to disease states. Survival rate was highest among the reported (82.8% for crude and 82.4% for disease free survival). Pelvic control rate in 6 weeks after the end of radiotherapy...
The Result of Combined Modality Treatment for Non-Hodgkin's Lymphoma of Head and Neck
Jae Cheol Kim, Sang Bo Kim, Samuel Ryu, In Kyu Park
Radiat Oncol J. 1990;8(2):255-260.
From April 1985 to September 1989, 26 patients with stage IandII non-Hodgkin's lymphoma of unfavorable histology localized in head and neck region were treated with combined modality (combination chemotherapy plus radiotherapy) at the Department of Therapeutic Radiology in Kyungpook National University Hospital. Of the 26 patients, 23 showed complete response and 3 partial response. Between these two groups there were...
Radiotherapeutic Result of waldeyer's Ring Lymphoma
Ju Ree Kim, Hyun Suk Suh
Radiat Oncol J. 1990;8(2):261-267.
Twenty patients with biopsy-proven Waldeyer's ring lymphoma were treated with radiotherapy between 1984 and 1990 at the Department of Radiation Therapy, Inje University Paik Hospital and seventeen evaluable patients were analysed retrospectively. Dose of radiation ranged from 35 to 50 gy to Waldeyer's ring structure with an additional 5 and 10 gy boost dose to the primary site. The lower...
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