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REVIEW ARTICLE 2021 October 25
Abscopal effect in the radio and immunotherapy
This review is devoted to a rare in clinical practice, but promising phenomenon of regression distant non-irradiated metastases in combination therapy of cancer patients. R. H. Mole in 1953 suggested introducing the term “abscopal effect” to denote the effect of ionizing radi...
ORIGINAL ARTICLE 2021 October 26
Computed tomography-based radiomic model predicts radiological response following stereotactic body radiation therapy in early-stage non-small-cell lung cancer and pulmonary oligo-metastases
Purpose: Radiomic models elaborate geometric and texture features of tumors extracted from imaging to develop predictors for clinical outcomes. Stereotactic body radiation therapy (SBRT) has been increasingly applied in the ablative treatment of thoracic tumors. This study aims ...
ORIGINAL ARTICLE 2021 September 3
Hyperfractionated radiotherapy for re-irradiation of recurrent esophageal cancer
Purpose: Re-irradiation is a treatment option for recurrent esophageal cancer patients with a history of radiotherapy, but there is a risk of severe late adverse effects. This study focused on the efficacy and safety of re-irradiation using hyperfractionated radiotherapy. Mate...
ORIGINAL ARTICLE 2021 October 26
Efficacy and safety of sequential neoadjuvant chemotherapy and short-course radiation therapy followed by delayed surgery in locally advanced rectal cancer: a single-arm phase II clinical trial with subgroup analysis between the older and young patients
Purpose: This study was performed to investigate the efficacy and safety of short-course radiation therapy (SCRT) and sequential chemotherapy followed by delayed surgery in locally advancer rectal cancer with subgroup analysis between the older and young patients. Materials and...
ORIGINAL ARTICLE 2021 December 7
Re-irradiation for recurrent or second primary head and neck cancer
Purpose: To investigate the efficacy and safety of intensity-modulated radiotherapy (IMRT)-based re-irradiation (reRT) for recurrent or second primary head and neck cancer (HNC). Materials and Methods: Patients who underwent IMRT-based reRT for recurrent or second primary HNC b...
ORIGINAL ARTICLE 2021 December 8
Clinical features and treatment outcomes of resected large cell neuroendocrine carcinoma of the lung
Purpose: Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a high-grade lung neuroendocrine tumor with a poor prognosis, similar to small cell lung cancer (SCLC). However, it remains unclear whether to treat LCNEC as non-small-cell lung cancer (NSCLC) or as SCLC. We revie...
ORIGINAL ARTICLE 2021 December 14
Prognostic value of the maximum standardized uptake value for the locoregional control in early glottic cancer
Purpose: To evaluate the prognostic value of the pretreatment maximum standardized uptake value (SUVmax) for locoregional control (LRC) of early glottic cancer treated with primary radiotherapy. Materials and Methods: We retrospectively reviewed the medical records of 101 patie...
ORIGINAL ARTICLE 2021 December 17
Impact of somatic mutations on clinical and pathologic outcomes in borderline resectable and locally advanced pancreatic cancer treated with neoadjuvant chemotherapy and stereotactic body radiotherapy followed by surgical resection
Purpose: The purpose of this study was to determine if somatic mutations are associated with clinical and pathologic outcomes in patients with borderline resectable pancreatic cancer (BRPC) or locally advanced pancreatic cancer (LAPC) who were treated with neoadjuvant chemothera...
ORIGINAL ARTICLE 2021 December 24
Clinical factors affecting the determination of radiotherapy-induced skin toxicity in breast cancer
Purpose: Radiotherapy is essential for the treatment of breast cancer (BC). However, adverse effects may occur in healthy tissue, during treatment and even after several months. Although it is known that this clinical radiosensitivity is multifactorial, the factors involved are ...
ORIGINAL ARTICLE 2021 August 17
Gamma-ray irradiation modulates PGRMC1 expression and the number of CD56+ and FoxP3+ cells in the tumor microenvironment of endometrial endometrioid adenocarcinoma
Purpose: Although the conventional gamma ray brachytherapy has been successful in treating endometrioid endometrial adenocarcinoma (EC), the molecular and cellular mechanisms of this anti-tumorigenic response remain unclear. Therefore, we investigated whether gamma ray irradiati...

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Current Issue
Volume 39(4); December 2021
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Review Article
247 Abscopal effect in the radio and immunotherapy
Alina M. Pevzner, Matvey M. Tsyganov, Marina K. Ibragimova, Nikolai V. Litvyakov
Radiat Oncol J. 2021;39(4):247-253.   Published online 2021 Oct 25     DOI: https://doi.org/10.3857/roj.2021.00115
                              
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Original Articles
Clinical Investigations
254 Computed tomography-based radiomic model predicts radiological response following stereotactic body radiation therapy in early-stage non-small-cell lung cancer and pulmonary oligo-metastases
Ben Man Fei Cheung, Kin Sang Lau, Victor Ho Fun Lee, To Wai Leung, Feng-Ming Spring Kong, Mai Yee Luk, Kwok Keung Yuen
Radiat Oncol J. 2021;39(4):254-264.   Published online 2021 Oct 26     DOI: https://doi.org/10.3857/roj.2021.00311
                              Supplementary      
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265 Hyperfractionated radiotherapy for re-irradiation of recurrent esophageal cancer
Kazuya Takeda, Haruo Matsushita, Rei Umezawa, Takaya Yamamoto, Yojiro Ishikawa, Noriyoshi Takahashi, Yu Suzuki, Keiichi Jingu
Radiat Oncol J. 2021;39(4):265-269.   Published online 2021 Sep 3     DOI: https://doi.org/10.3857/roj.2021.00325
                              
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270 Efficacy and safety of sequential neoadjuvant chemotherapy and short-course radiation therapy followed by delayed surgery in locally advanced rectal cancer: a single-arm phase II clinical trial with subgroup analysis between the older and young patients
Alimohammad Bananzadeh, Ali Akbar Hafezi, NamPhong Nguyen, Shapour Omidvari, Ahmad Mosalaei, Niloofar Ahmadloo, Mansour Ansari, Mohammad Mohammadianpanah
Radiat Oncol J. 2021;39(4):270-278.   Published online 2021 Oct 26     DOI: https://doi.org/10.3857/roj.2021.00654
                                 Cited By 1
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279 Re-irradiation for recurrent or second primary head and neck cancer
Hye In Lee, Jin Ho Kim, Soon-Hyun Ahn, Eun-Jae Chung, Bhumsuk Keam, Keun-Yong Eom, Woo-Jin Jeong, Ji-Won Kim, Chan Woo Wee, Hong-Gyun Wu
Radiat Oncol J. 2021;39(4):279-287.   Published online 2021 Dec 7     DOI: https://doi.org/10.3857/roj.2021.00640
                              
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288 Clinical features and treatment outcomes of resected large cell neuroendocrine carcinoma of the lung
Jin Young Moon, Seo Hee Choi, Tae Hyung Kim, Joongyo Lee, Ji Hoon Pyo, Yong Tae Kim, Seo Jin Lee, Hong In Yoon, Jaeho Cho, Chang Geol Lee
Radiat Oncol J. 2021;39(4):288-296.   Published online 2021 Dec 8     DOI: https://doi.org/10.3857/roj.2021.00423
                              Supplementary      
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297 Prognostic value of the maximum standardized uptake value for the locoregional control in early glottic cancer
Donghyun Kim, Yongkan Ki, Jihyeon Joo, Hosang Jeon, Dahl Park, Jiho Nam, Wontaek Kim
Radiat Oncol J. 2021;39(4):297-303.   Published online 2021 Dec 14     DOI: https://doi.org/10.3857/roj.2021.00507
                              
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304 Impact of somatic mutations on clinical and pathologic outcomes in borderline resectable and locally advanced pancreatic cancer treated with neoadjuvant chemotherapy and stereotactic body radiotherapy followed by surgical resection
Abhinav V. Reddy, Colin S. Hill, Shuchi Sehgal, Ding Ding, Amy Hacker-Prietz, Jin He, Lei Zheng, Joseph M. Herman, Jeffrey Meyer, Amol K. Narang
Radiat Oncol J. 2021;39(4):304-314.   Published online 2021 Dec 17     DOI: https://doi.org/10.3857/roj.2021.00815
                              Supplementary      
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315 Clinical factors affecting the determination of radiotherapy-induced skin toxicity in breast cancer
Elisa Eugenia Córdoba, Ezequiel Lacunza, Alba Mabel Güerci
Radiat Oncol J. 2021;39(4):315-323.   Published online 2021 Dec 24     DOI: https://doi.org/10.3857/roj.2020.00395
                              
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Biology contribution
324 Gamma-ray irradiation modulates PGRMC1 expression and the number of CD56+ and FoxP3+ cells in the tumor microenvironment of endometrial endometrioid adenocarcinoma
Dmitry Aleksandrovich Zinovkin, Yulia Anatolievna Lyzikova, Eldar Arkadievich Nadyrov, Daniil Rudolfovich Petrenyov, Jale Yuzugulen, Md Zahidul Islam Pranjol
Radiat Oncol J. 2021;39(4):324-333.   Published online 2021 Aug 17     DOI: https://doi.org/10.3857/roj.2021.00472
                              
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