Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials
Jae Ho Kim, Kenneth A. Jenrow, Stephen L. Brown
Radiat Oncol J. 2014;32(3):103-115. Published online 2014 Sep 30 DOI: https://doi.org/10.3857/roj.2014.32.3.103
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Frontiers in Cardiovascular Medicine.2021;[Epub] CrossRef Psychotherapy with Music Intervention Improves Anxiety, Depression and the Redox Status in Breast Cancer Patients Undergoing Radiotherapy: A Randomized Controlled Clinical Trial
Patrizia Zeppegno, Marco Krengli, Daniela Ferrante, Marco Bagnati, Vincenzo Burgio, Serena Farruggio, Roberta Rolla, Carla Gramaglia, Elena Grossini
Cancers.2021; 13(8): 1752. CrossRef Adverse Vascular Functional and Structural Changes Secondary to Breast Cancer and its Treatments with Adjuvant Therapy: a Systematic Review
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Molecules.2021; 26(9): 2573. CrossRef Radiation-Induced Bilateral Oculomotor Nerve Palsy 20 Years After Radiation Treatment
Justin J. Grassmeyer, J. Americo Fernandes, Jason T. Helvey, Sachin Kedar
Neurology.2021; 96(20): 955. CrossRef The role of melatonin on radiation-induced pneumonitis and lung fibrosis: A systematic review
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Marina Filimonova, Alina Saburova, Victoria Makarchuk, Ljudmila Shevchenko, Valentina Surinova, Vadim Yuzhakov, Nina Yakovleva, Larisa Sevankaeva, Vyacheslav Saburov, Sergey Koryakin, Petr Shegay, Andrey Kaprin, Sergey Ivanov, Alexander Filimonov
International Journal of Molecular Sciences.2021; 22(17): 9340. CrossRef Devastated Bladder Outlet in Pelvic Cancer Survivors: Issues on Surgical Reconstruction and Quality of Life
Francisco E. Martins, Henriette Veiby Holm, Nicolaas Lumen
Journal of Clinical Medicine.2021; 10(21): 4920. CrossRef Clinical factors affecting the determination of radiotherapy-induced skin toxicity in breast cancer
Elisa Eugenia Córdoba, Ezequiel Lacunza, Alba Mabel Güerci
Radiation Oncology Journal.2021; 39(4): 315. CrossRef Phytochemicals: Potential Therapeutic Modulators of Radiation Induced Signaling Pathways
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Antioxidants.2021; 11(1): 49. CrossRef Radiation activates myeloperoxidase (MPO) to generate active chlorine species (ACS) via a dephosphorylation mechanism - inhibitory effect of LGM2605
Om P. Mishra, Anatoliy V. Popov, Ralph A. Pietrofesa, Wei-Ting Hwang, Mark Andrake, Eiko Nakamaru-Ogiso, Melpo Christofidou-Solomidou
Biochimica et Biophysica Acta (BBA) - General Subjects.2020; 1864(7): 129548. CrossRef Synergetic role of senna and fennel extracts as antioxidant, anti-inflammatory and anti-mutagenic agents in irradiated human blood lymphocyte cultures
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Journal of Radiation Research and Applied Sciences.2020; 13(1): 191. CrossRef Assessment of antioxidant, immune enhancement, and antimutagenic efficacy of fennel seed extracts in irradiated human blood cultures
Alyaa Farid, Dina Kamel, Sherien Abdelwahab Montaser, Mahmoud Mohamed Ahmed, Mona El Amir, Azza El Amir
Journal of Radiation Research and Applied Sciences.2020; 13(1): 260. CrossRef TGF-β in radiotherapy: Mechanisms of tumor resistance and normal tissues injury
Bagher Farhood, Ehsan khodamoradi, Mojtaba Hoseini-Ghahfarokhi, Elahe Motevaseli, Hanifeh Mirtavoos-Mahyari, Ahmed Eleojo Musa, Masoud Najafi
Pharmacological Research.2020; 155: 104745. CrossRef Serum Proteins as New Biomarkers for Whole-Body Exposure to High- and Low-LET Ionizing Radiation
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Dose-Response.2020;[Epub] CrossRef Plasminogen is a master regulator and a potential drug candidate for the healing of radiation wounds
Mahsa Fallah, Emil Viklund, Assar Bäckman, Jessica Brodén, Bertil Lundskog, Michael Johansson, Michael Blomquist, Malgorzata Wilczynska, Tor Ny
Cell Death & Disease.2020;[Epub] CrossRef Therapeutic Reversal of Radiotherapy Injury to Pro-fibrotic Dysfunctional Fibroblasts In Vitro Using Adipose-derived Stem Cells
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Plastic and Reconstructive Surgery - Global Open.2020; 8(3): e2706. CrossRef Modulation of radiation‐induced damage of human glomerular endothelial cells by SMPDL3B
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The FASEB Journal.2020; 34(6): 7915. CrossRef Fractionated radiation suppresses Kruppel-like factor 2 pathway to a greater extent than by single exposure to the same total dose
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Scientific Reports.2020;[Epub] CrossRef Radiation-Induced Lung Injury
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Journal of oncology: diagnostic radiology and radiotherapy.2020; 3(2): 9. CrossRef Gold nanoparticle mediated radiation response among key cell components of the tumour microenvironment for the advancement of cancer nanotechnology
Kyle Bromma, Leah Cicon, Wayne Beckham, Devika B. Chithrani
Scientific Reports.2020;[Epub] CrossRef Role of microRNA in forming breast carcinoma
Momi Saikia, Sunanda Paul, Supriyo Chakraborty
Life Sciences.2020; 259: 118256. CrossRef Comparing the Role of the p53 Gene and Telomerase Enzyme in ‘Accelerated Aging Due to Cancer’: A Literature Review
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Cureus.2020;[Epub] CrossRef Can a comparison of clinical and deep space irradiation scenarios shed light on the radiation response of the brain?
Charles Limoli
The British Journal of Radiology.2020; 93(1115): 20200245. CrossRef Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System Nasrul Wathoni, An Ny Nguyen, Agus Rusdin, Abd Kakhar Umar, Ahmed Fouad Abdelwahab Mohammed, Keiichi Motoyama, I Made Joni, Muchtaridi Muchtaridi
Drug Design, Development and Therapy.2020; Volume 14: 4387. CrossRef Prostate Cancer Radiotherapy: Increased Biochemical Control and Late Toxicity in Men With Medication Allergies
William Tyler Turchan, Stanley I Gutiontov, Michael T Spiotto, Stanley L Liauw
JNCI Cancer Spectrum.2020;[Epub] CrossRef Radiotherapy and Its Impact on the Nervous System of Cancer Survivors
Gautam Kumar, Priyadarshini Dutta, Vipan K. Parihar, Mallikarjuna R. Chamallamudi, Nitesh Kumar
CNS & Neurological Disorders - Drug Targets .2020; 19(5): 374. CrossRef Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss
Alina Wiesemann, Julia Ketteler, Alexis Slama, Florian Wirsdörfer, Thomas Hager, Katharina Röck, Daniel R. Engel, Jens W. Fischer, Clemens Aigner, Verena Jendrossek, Diana Klein
Antioxidants & Redox Signaling.2019; 30(2): 213. CrossRef The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
Ping Zhou, Bing Lin, Peng Wang, Tao Pan, Shun Wang, Weisi Chen, Shaowen Cheng, Sha Liu
Journal of Radiation Research.2019; 60(1): 17. CrossRef Tumor-Infiltrating T Cell Receptor-Beta Repertoires are Linked to the Risk of Late Chemoradiation-Induced Temporal Lobe Necrosis in Locally Advanced Nasopharyngeal Carcinoma
LiFu Wu, Yih-Lin Chung
International Journal of Radiation Oncology*Biology*Physics.2019; 104(1): 165. CrossRef Gut microbiota: implications for radiotherapy response and radiotherapy-induced mucositis
Ghanyah Al-Qadami, Ysabella Van Sebille, Hien Le, Joanne Bowen
Expert Review of Gastroenterology & Hepatology.2019; 13(5): 485. CrossRef Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy
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Frontiers in Immunology.2019;[Epub] CrossRef Design and synthesis a mitochondria-targeted dihydronicotinamide as radioprotector
Yu-Rui Zhang, Jun-Ying Wang, Yuan-Yuan Li, Yuan-Yuan Meng, Yuan Zhang, Fu-Jun Yang, Wen-Qing Xu
Free Radical Biology and Medicine.2019; 136: 45. CrossRef Outcomes of reconstructive urinary tract surgery after pelvic radiotherapy
Bogdan Toia, Jai Seth, Hazel Ecclestone, Mahreen Pakzad, Rizwan Hamid, Tamsin Greenwell, Jeremy Ockrim
Scandinavian Journal of Urology.2019; 53(2-3): 156. CrossRef Free vastus lateralis musculocutaneous flap transfer for radiation-induced chest wall fistula combined with osteomyelitis
Xia Hong, Zhongliang He, Lifeng Shen, Xueming He
Medicine.2019; 98(22): e15859. CrossRef Staged Treatment of Chest Wall Radiation-Induced Ulcer With Negative Pressure Wound Therapy and Latissimus Dorsi Myocutaneous Flap Transplantation
Xiuqi Li, Fan Zhang, Xujin Liu, Zilong Cao, Pei Liu, Lin Xia, Min Du
Journal of Craniofacial Surgery.2019; 30(5): e450. CrossRef Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells
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Genes and Environment.2019;[Epub] CrossRef Understanding the mechanism of radiation induced fibrosis and therapy options
Asim Ejaz, Joel S. Greenberger, Peter J. Rubin
Pharmacology & Therapeutics.2019; 204: 107399. CrossRef Carvacrol and Thymol Modulate the Cross-Talk between TNF-α and IGF-1 Signaling in Radiotherapy-Induced Ovarian Failure
Yasmen F. Mahran, Amira M. Badr, Alhanouf Aldosari, Raghad Bin-Zaid, Hind N. Alotaibi, Francisco J. Romero
Oxidative Medicine and Cellular Longevity.2019; 2019: 1. CrossRef Plasma Fibrinogen-Like 1 as a Potential Biomarker for Radiation-Induced Liver Injury
Na-Kyung Han, Myung Gu Jung, Ye Ji Jeong, Yeonghoon Son, Su Chul Han, Seungwoo Park, Young-Bin Lim, Yoon-Jin Lee, Sung-Ho Kim, Su Cheol Park, Hae-June Lee
Cells.2019; 8(9): 1042. CrossRef The CD73/Ado System—A New Player in RT Induced Adverse Late Effects
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Cancers.2019; 11(10): 1578. CrossRef Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors
Jennifer L Guida, Tim A Ahles, Daniel Belsky, Judith Campisi, Harvey Jay Cohen, James DeGregori, Rebecca Fuldner, Luigi Ferrucci, Lisa Gallicchio, Leonid Gavrilov, Natalia Gavrilova, Paige A Green, Chamelli Jhappan, Ronald Kohanski, Kevin Krull, Jeanne Ma
JNCI: Journal of the National Cancer Institute.2019; 111(12): 1245. CrossRef Radio-detoxified LPS alters bone marrow-derived extracellular vesicles and endothelial progenitor cells
Hargita Hegyesi, Nikolett Sándor, Géza Sáfrány, Virág Lovas, Árpád Kovács, Angéla Takács, László Kőhidai, Lilla Turiák, Ágnes Kittel, Krisztina Pálóczi, Lóránd Bertók, Edit Irén Buzás
Stem Cell Research & Therapy.2019;[Epub] CrossRef Radiation-induced Osteomyelitis/Osteonecrosis of the Rib: SPECT/CT Imaging for Successful Surgical Management
Mariko Hamada, Tadaki Nakahara, Masaki Yazawa, Shuji Mikami, Kazuo Kishi
Plastic and Reconstructive Surgery - Global Open.2019; 7(12): e2536. CrossRef Melatonin Modulates Regulation of NOX2 and NOX4 Following Irradiation in the Lung
Masoud Najafi, Alireza Shirazi, Elahe Motevaseli, Ghazale Geraily, Peyman Amini, Leila Farhadi Tooli, Dheyauldeen Shabeeb
Current Clinical Pharmacology.2019; 14(3): 224. CrossRef The Use of Radioprotective Agents to Prevent Effects Associated with Aging
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Biology Bulletin.2019; 46(12): 1657. CrossRef Annexin A1‑mediated inhibition of inflammatory cytokines may facilitate the resolution of inflammation in acute radiation‑induced lung injury
Gaohua Han, Kaijin Lu, Wansong Xu, Sihui Zhang, Junxing Huang, Chunlei Dai, Guangzhi Sun, Jun Ye
Oncology Letters.2019;[Epub] CrossRef Neutrophil‐lymphocyte ratio and a dosimetric factor for predicting symptomatic radiation pneumonitis in non‐small‐cell lung cancer patients treated with concurrent chemoradiotherapy
Yun Hee Lee, Hoon‐Sik Choi, Hojin Jeong, Ki Mun Kang, Jin Ho Song, Won Sup Lee, Gyeong‐Won Lee, Haa‐Na Song, Hoon‐Gu Kim, Myoung Hee Kang, Dong Yoon Rhee, Bae Kwon Jeong
The Clinical Respiratory Journal.2018; 12(3): 1264. CrossRef Heart in space: effect of the extraterrestrial environment on the cardiovascular system
Richard L. Hughson, Alexander Helm, Marco Durante
Nature Reviews Cardiology.2018; 15(3): 167. CrossRef Outcome of 9 dogs treated with stereotactic radiation therapy for primary or metastatic vertebral osteosarcoma
K. E. Swift, S. M. LaRue
Veterinary and Comparative Oncology.2018;[Epub] CrossRef Comparative study of radioprotective effects of selenium nanoparticles and sodium selenite in irradiation-induced nephropathy of mice model
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International Journal of Radiation Biology.2018; 94(1): 17. CrossRef Cerebral blood flow changes after radiation therapy identifies pseudoprogression in diffuse intrinsic pontine gliomas
Raphael Calmon, Stephanie Puget, Pascale Varlet, Volodia Dangouloff-Ros, Thomas Blauwblomme, Kevin Beccaria, David Grevent, Christian Sainte-Rose, David Castel, Marie-Anne Debily, Christelle Dufour, Stéphanie Bolle, Frederic Dhermain, Ana Saitovitch, Moni
Neuro-Oncology.2018; 20(7): 994. CrossRef Post-irradiation protective effects of ectoine on brain and testicles in male mice
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Pharmacological Reports.2018; 70(2): 304. CrossRef 18β-Glycyrrhetinic acid mitigates radiation-induced skin damage via NADPH oxidase/ROS/p38MAPK and NF-κB pathways
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NeuroImage: Clinical.2018; 19: 252. CrossRef Perfusion magnetic resonance imaging changes in normal appearing brain tissue after radiotherapy in glioblastoma patients may confound longitudinal evaluation of treatment response
Markus Fahlström, Erik Blomquist, Tufve Nyholm, Elna-Marie Larsson
Radiology and Oncology.2018; 52(2): 143. CrossRef Receptor tyrosine kinase signaling in cancer radiotherapy and its targeting for tumor radiosensitization
Poushali Bhattacharya, Neena G. Shetake, Badri N. Pandey, Amit Kumar
International Journal of Radiation Biology.2018; 94(7): 628. CrossRef Potential of serum microRNAs as biomarkers of radiation injury and tools for individualization of radiotherapy
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Translational Research.2018; 201: 71. CrossRef Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review
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Critical Reviews in Oncology/Hematology.2018; 129: 13. CrossRef Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging
Satyendra K. Singh, Shweta Singh, Stephen Gadomski, Lei Sun, Alexander Pfannenstein, Valentin Magidson, Xiongfong Chen, Serguei Kozlov, Lino Tessarollo, Kimberly D. Klarmann, Jonathan R. Keller
Cell Stem Cell.2018; 23(2): 252. CrossRef Radiation Induces Apoptosis and Osteogenic Impairment through miR-22-Mediated Intracellular Oxidative Stress in Bone Marrow Mesenchymal Stem Cells
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Stem Cells International.2018; 2018: 1. CrossRef Radiation therapy damages external anal sphincter and perineal muscle floor
Federica Domati, Luca R. Bonetti, Valeria Barresi, Maurizio Zizzo, Antonio Manenti
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Stamati Morias, Loredana G. Marcu, Michala Short, Eileen Giles, Andrew Potter, Justin Shepherd, Thanh Gierlach, Eva Bezak
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Jae Ho Kim, Kenneth A. Jenrow, Stephen L. Brown
Radiation Oncology Journal.2018; 36(3): 172. CrossRef Plasminogen activation is required for the development of radiation-induced dermatitis
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Cell Death & Disease.2018;[Epub] CrossRef Impact of Unilateral Orbital Radiotherapy on the Structure and Function of Bilateral Human Meibomian Gland
Di Chen, Xiaowei Liu, Ying Li, Hui Guan, Fuquan Zhang
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Yeona Cho, Jun Won Kim, Ki Chang Keum, Chang Geol Lee, Hei Cheul Jeung, Ik Jae Lee
Frontiers in Oncology.2018;[Epub] CrossRef Combining Radiotherapy and Immunotherapy in Lung Cancer: Can We Expect Limitations Due to Altered Normal Tissue Toxicity?
Florian Wirsdörfer, Simone De Leve, Verena Jendrossek
International Journal of Molecular Sciences.2018; 20(1): 24. CrossRef Panax ginseng Meyer prevents radiation-induced liver injury via modulation of oxidative stress and apoptosis
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Jerome Lacombe, Frederic Zenhausern
Critical Reviews in Oncology/Hematology.2017; 109: 69. CrossRef Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours
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Nature Reviews Neurology.2017; 13(1): 52. CrossRef Genetic Variants in MTHFR Gene Predict ≥ 2 Radiation Pneumonitis in Esophageal Squamous Cell Carcinoma Patients Treated with Thoracic Radiotherapy
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PLOS ONE.2017; 12(1): e0169147. CrossRef Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule Are Induced by Ionizing Radiation on Lymphatic Endothelium
María E. Rodriguez-Ruiz, Saray Garasa, Inmaculada Rodriguez, Jose Luis Solorzano, Benigno Barbes, Alba Yanguas, Alvaro Teijeira, Iñaki Etxeberria, José Javier Aristu, Cornelia Halin, Ignacio Melero, Ana Rouzaut
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Radiation Oncology Journal.2017; 35(1): 48. CrossRef Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy
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International Journal of Radiation Biology.2017; 93(9): 851. CrossRef Atorvastatin mitigates testicular injuries induced by ionizing radiation in mice
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Radiation and Environmental Biophysics.2017; 56(4): 413. CrossRef Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differentiated thyroid cancer
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International Journal of Molecular Sciences.2017; 18(11): 2233. CrossRef The neck burn scar contracture: a concept of effective treatment
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Burns & Trauma.2017;[Epub] CrossRef Prophylactic amifostine prevents a pathologic vascular response in a murine model of expander-based breast reconstruction
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Current Problems in Cancer.2016; 40(1): 10. CrossRef Polymorphic Variants in Oxidative Stress Genes and Acute Toxicity in Breast Cancer Patients Receiving Radiotherapy
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Cancer Research and Treatment.2016; 48(3): 948. CrossRef POINT: Does Low-Dose Oxygen Expose Patients With COPD to More Radiation-Like Risks Than Patients Without COPD? Yes
Vincent J. Kopp, Joseph M. Stavas
Chest.2016; 149(2): 303. CrossRef Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1)
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Biochemical Pharmacology.2016; 103: 140. CrossRef The Influence of C-Ions and X-rays on Human Umbilical Vein Endothelial Cells
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