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J Korean Soc Ther Radiol > Volume 9(2); 1991 > Article
Journal of the Korean Society for Therapeutic Radiology 1991;9(2): 325-331.
The Role of Radiation Therapy in Management of Wilms' Tumor
Mi Sook Kim, Il Han Kim, Hyong Geun Yun
Department of Therapeutic Radiology, College of Medicine, Seoul, National University, Korea.
Treatment results of 28 patients with Wilms' Tumor who received radiation therapy at the Department of Therapeutic Radiology, Seoul National University Hospital from 1979 to 1988 were analyzed. The median follow-up period for the survivors was 40 months. The local control and overall survival rate at 3 years were 78.1% and 67.4%, respectively. The local control was not affected by age. The local control rates for favorable histology (FH) and unfavorable histology (UH) were 83.3% and 62.5%, respectively. In FH, the local control rates of stage II and III were not different (83.3% vs 100.0%). In UH, the control rates of stage I/II and stage III were 83.3% and 0%, respectively. Poor local control was correlated with involvement of lymph node (50.0% vs 87.5%). Radiotherapy delayed 10 or more days after operatio resulted in poorer local control than that without delay(p<0.05). Thus radiotherapy contributed to reduction of local recurrence in patients with high risk factor without increased severe comlication. It is suggested that bulky unresectable mass might need a more intensified treatment
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