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J Korean Soc Ther Radiol > Volume 9(2); 1991 > Article
Journal of the Korean Society for Therapeutic Radiology 1991;9(2): 293-301.
Clinical Significance of Plasma CEA Levels in the Patients with Cervical Carcinoma during Follow-Up
Sung Beom Ban, Joo Young Kim, Myung Sun Choi, Joong Yeol Rha, Min Jae Lee
1Department of Radiation Oncology, Myung-ShinClinic, Seoul, Korea.
2Department of Obstetrics and Gynecology, Korea University School of Medicine, Seoul, Korea.
3Department of nuclear Medicine, Korea University School of Medicine, Seoul, Korea.
Carcinoembryonic antigen (CEA) has been studied in the field of gynecologic malignancy to determine whether it can be used as a tumor marker for early detection of recurrence or evaluation of therapeutic results. From January 1985 through December 1989, a total of 239 cervical cancer patients were entered for an analysis of plasma CEA level in the group with cervical cancer compared to the control group consisting of 65 normal healthy women and 18 women with benign gynecologic disease. Plasma CEA levels appear to be directly related with the tumor extension and as stages advance, the incidence of patients with abnormal plasma CEA levels is increased. Also, there seems to be a little higher incidence of abnormal CEA levels in patients with adenocarcinomas or adenosquamous carcinoma but not statistically significant because of small number of patients. When the patients developed recurrence, plasma CEA levels are markedly elevated in the majority, particularly in patients with hepatic metastases. In conclusion, serial plasma CEA checks could be used to detect recurrence during follow-up after treatment of cervical cancer.
Key Words: CEA, cervix cancer
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