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J Korean Soc Ther Radiol > Volume 9(1); 1991 > Article
Journal of the Korean Society for Therapeutic Radiology 1991;9(1): 87-92.
IORT in Gastric Cancer
Myung Se Kim, Cheol Hoon Kang, Sung Kyu Kim, Sun Kyo Song, Koing Bo Kwan, Heung Dae Kim
1Department of Therapeutic Radiology, College of Medicine, Yeungnam University, Taegu, Korea.
2Department of General Surgery, College of Medicine, Yeungnam University, Taegu, Korea.
3Department of Anesthesiology, College of Medicine, Yeungnam University, Taegu, Korea.
Total 28 patients with respectable, locally advanced gastric cancer were entered in our prospective randomized study from June 15, 1988 to Sep. 15, 1990 in Yeungnam University Hospital. This study consisted of curative resection, IORT, external irradiation and combination of chemotherapy. Twenty-four of 28 patients were treated with single dose of 1500 cGy per fraction, 5 days per week was started within 4th weeks postoperative days. Various chemotherapy with or without external irradiation were added for reducing hematogenous and/or peritoneal dissemination and determination of complication of each arm. Duration of follow up was 4~31 months. No serious complication related with radiation were reported compare to resection and chemotherapy only group. Although our follow up period is too short to draw any conclusion, IORT appears to improve local control, hopely further survival. Continuous follow up should be needed for evaluation of real therapeutic gain such as complication vs. improved survival.
Key Words: IORT, Prospective randomized trial, Locally advanced gastric cancer complication, Local control
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