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J Korean Soc Ther Radiol > Volume 6(1); 1988 > Article
Journal of the Korean Society for Therapeutic Radiology 1988;6(1): 75-80.
Clinical Applications of Microwave and Ultrasound in Hyperthermia: Preliminary Results
Kyoung Hwan Koh, Young Hwan Park, Chul Koo Cho, Seong Yul Yoo
Department of Therapeutic Radiology, Korea Cancer Center Hospital, KAERI, Seoul, Korea.
ABSTRACT
Twenty seven lesions of 25 patients with locally advanced malignant tumors were treated with combined hyperthermia introduced by microwave and ultrasound and radiotherpy. Most of all patients were failed with previous conventional therapeutic trial. Hyperthermia had been done immediately after radiotherapy, twice a week, 43degree C for one hour and radiotherapy had been done 5 fractions per week with fraction size of 2 gy up to 30 to 60 gy. Conclusions are as follows. Total response rate (PR+PR) to thermoradiotherapy with microwave and ultrasound was 81%. Tumor depth, minimum temperature of tumor center, number of heat fraction and radiation dose were statistically significant factors affecting response. Hyperthermia with microwave and ultrasound can be used efficiently to control locally advanced malignant disease whether previously received near tolerance dose of radiotherapy or not.
Key Words: Microwave, Ultrasound, Hyperthermia, Radiotherapy, Malignant Tumor
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