Angiofollicular Lymph Node Hyperplasia(=Castleman's Disease): Report of A Case

Gil,  Hak Jun; Oh,  Yoon Kyung; Yoon,  Sei Chul; Shinn,  Kyung Sub; Bahk,  Yong Whee

J Korean Soc Ther Radiol > Volume 5(1); 1987 > Article

Case Report

Journal of the Korean Society for Therapeutic Radiology 1987;5(1): 37-42.

Angiofollicular Lymph Node Hyperplasia(=Castleman's Disease): Report of A Case

Hak Jun Gil, Yoon Kyung Oh, Sei Chul Yoon, Kyung Sub Shinn, Yong Whee Bahk

Division of Radiation Therapy, Kangna, St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.

ABSTRACT

Angiofollicular lymph node hyperplasia (AFLNH) with well marginated lymphoid masses, is a rare benign disease of unknown etiology. The majority of the disease develop intrathoracically. Histologically this disease can be divided into the hyaline-vascular and the plasma cell types with the hyaline-vascular type prevailing. The plasma cell variant has been associated with nephritic syndrome, anemia, growth failure, fever, hyperglobulinemia, peripheral neuropathy, and hypoalbuminemia. Surgical resection is known to be treatment of choice in most cases, and radiotherapy is reserved for advanced, unresectable lesions. We report a complete remission of AFLNH in a case treated by surgical excision followed by irradiation.

Key Words: Angiofollicular lymph node hyperplasia, Hyaline-vascular type, Plasma cell type, radiotherapy