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J Korean Soc Ther Radiol > Volume 4(1); 1986 > Article
Journal of the Korean Society for Therapeutic Radiology 1986;4(1): 45-50.
A Study of Relationship Between PPC(Probability of Primary Clearance: a multivariate modeling system predicting tumor clearance proposed by RTOG) and Survival in the Patients with Carcinoma of the Nasopharynx Following Radiation Therapy
Kwan Ho Cho, Kyung Ran Park, Won Yong Oh, Mison Chun, Chang Ok Suh, Gwi Eon Kim, J K Loh
Department of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center, Korea.
RTOG proposed a multivariate modeling system predicting the response of head and neck cancers to radiation therapy in 1984. The aim of this study was to verify whether PPC (Probability of primary clearance calculated by a multivariate modeling system) had any correlation with the survival in the patients with carcinoma of the nasopharynx following radiation therapy. Analysing 81 patients with carcinoma of the nasopharynx treated with radiotherapy between January 1, 1971 and December 31, 1983 at Yonsei University College of Medicine, Yonsei Cancer Center, the actuarial 5 year survival rate was 36% and median survival was 39 months. The survivals for Group 1 (27 who had more than 80% of PPC), Group 2 (20 who had between 71 and 80% of PPC), and Group 3 (29 who had less than 71% of PPC) were 66% (median survival months: more than 72), 27% (31), and 4% (12) respectively. There was a definite correlation between PPC and survival among the three groups.
Key Words: Nasopharyngeal carcinoma, Radiation therapy, Probability of primary clearance, Survival
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