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J Korean Soc Ther Radiol > Volume 3(1); 1985 > Article
Journal of the Korean Society for Therapeutic Radiology 1985;3(1): 9-12.
Radiosensitivity and Dose-urvival Characteristics of Crypt Cells of Mouse Jejunum
Seoung Jae Huh, Charn Il Park
1Department of Radiology, College of Medicine, Soonchunhyang University, Korea.
2Department of Therapeutic Radiology, College of Medicine, Seoul University, Korea.
To determine the radiosensitivity and dose-urvival characteristics of jejunal crypt cells, experimental study was done using total 40 mice. Single irradiation of 1,000rad to 1,600rad was delivered to whole bodies of mice, using a cesium 137 animal irradiator. The number of regenerating crypts per jejunal circumference was counted, by using a jejunal crypt cell assay technique, and dose response curve was measured. The average number of jejunal crypt per circumference in control group was 140+/-10. Mean lethal dose(D0) of mouse jejunal crypt cell was 135rad.
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