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J Korean Soc Ther Radiol > Volume 1(1); 1983 > Article
Journal of the Korean Society for Therapeutic Radiology 1983;1(1): 61-68.
CNS Involvement in the Non-odgkin's Lymphoma
Chang Ok Suh, Gwi Eon Kim, Chang Yun Park, Byung Soo Kim
Department of Radiology Yonsei University Medical College, Korea.
Two cases of primary malignant lymphoma of the brain and six cases of secondary CNS lymphoma seen at Yonsei cancer center, radiotherapy department for recent 4 years are presented. Primary lymphomas revealed single tumor mass on corpus callosum area and secondary lymphoma were intracranial (3 cases) or leptomeningeal type (3 cases). Histology of primary lymphoma were reticulum cell sarcoma and secondary lymphomas were either diffuse histiocytic or diffuse poorly differentiated lymphocytic lymphoma. All patients showed good response to radiation. Two patients with primary CNS lymphoma and two of six secondary CNS lymphoma are alive after radiotherapy (34, 31, 26, 12 months). But the prognosis of secondary CNS lymphoma is grave, because of progressive systemic disease. Incidence, risk factors, diagnosis and therapeutic management of CNS involvement are also discussed.
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