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J Korean Soc Ther Radiol > Volume 1(1); 1983 > Article
Journal of the Korean Society for Therapeutic Radiology 1983;1(1): 5-10.
An Experimental Study on Late Change of the Irradiated Lung
Hong Sik Byun, Charn Il Park, Man Chung Han
Department of Radiology, College of Medicine, Seoul National University, Korea.
To evaluate late change of irradiated lung, a total of 60 rats was irradiated on right lungfield with a single dose of 2000 rads using Co-0 teletherapy unit. Follow-p roentgenographic and histopathologic study was performed three, six and twelve months after irradiation in each group of 20 rats. The results were as follows: 1.Chest roentgenographic findings in the order of frequency were pneumonic consolidation, atelectasis, and pleural effusion in 3-onth follow-p group; atelectasis, fibrostreaky infiltration, and pneumonic consolidation in 6-onth follow-p; and normal, and normal, and atelectasis in 12-onths follow-p group. 2. Main histopathological findings were alveolar and interstitial exudates, and diffuse infiltration of inflammatory cells in 3-onth follow-p group; thickening of interstitium and vascular wall in 6-onth follow-p group; and interstitial fibrosis in 12-onth follow-p group.
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