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J Korean Soc Ther Radiol Oncol > Volume 28(2); 2010 > Article
The Journal of the Korean Society for Therapeutic Radiology and Oncology 2010;28(2): 111-116. doi: https://doi.org/10.3857/jkstro.2010.28.2.111
Nonfunctional Parathyroid Carcinoma: A Case Report
Sang Gyu Choi
Department of Radiation Oncology, Dankook University Hospital, Cheonan, Korea. am2ran@hanmail.net
ABSTRACT
Parathyroid carcinoma is a rare endocrine malignancy accounting for 0.5% to 4.0% of all cases of hyperparathyroidism and commonly present as hypercalcemia and parathyroid hormone (PTH) elevation. Nonfunctional parathyroid carcinoma does not show symptoms of hyperparathyroidism and only showed a vague indication of being pathologic, even when detected late. The optimal treatment is en bloc resection of the cancer, but frequent local recurrence after surgery has been reported. Adjuvant local treatment such as radiotherapy may improve the likelihood local control in cases with incompletely resected or microscopic residual tumor. The results of this study point to a case of nonfunctional parathyroid carcinoma treated by external beam radiotherapy after en-bloc resection of cancer.
Key Words: Nonfunctional parathyroid carcinoma, Radiotherapy
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