A Dose Volume Histogram Analyzer Program for External Beam Radiotherapy |
Jin Sung Kim, Myonggeun Yoon, Sung Yong Park, Jung Suk Shin, Eunhyuk Shin, Sang Gyu Ju, Youngyih Han, Yong Chan Ahn |
1Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University, College of Medicine, Seoul. youngyih.han@samsung.com 2Proton Therapy Center, National Cancer Center, Ilsan, Korea. |
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ABSTRACT |
PURPOSE: To provide a simple research tool that may be used to analyze a dose volume histogram from different radiation therapy planning systems for NTCP (Normal Tissue Complication Probability), OED (Organ Equivalent Dose) and so on. MATERIALS AND METHODS: A high-level computing language was chosen to implement Niemierko's EUD, Lyman-Kutcher-Burman model's NTCP, and OED. The requirements for treatment planning analysis were defined and the procedure, using a developed GUI based program, was described with figures. The calculated data, including volume at a dose, dose at a volume, EUD, and NTCP were evaluated by a commercial radiation therapy planning system, Pinnacle (Philips, Madison, WI, USA) for comparison.
RESULTS: The volume at a special dose and a dose absorbed in a volume on a dose volume histogram were successfully extracted using DVH data of several radiation planning systems. EUD, NTCP and OED were successfully calculated using DVH data and some required parameters in the literature. CONCLUSION: A simple DVH analyzer program was developed and has proven to be a useful research tool for radiation therapy. |
Key Words:
Dose volume histogram, Normal tissue complication probability, Organ equivalent dose, Software |
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