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J Korean Soc Ther Radiol Oncol > Volume 24(3); 2006 > Article
The Journal of the Korean Society for Therapeutic Radiology and Oncology 2006;24(3): 201-206.
Combined Arthroscopic Gross Total Synovectomy and Radiotherapy for Diffuse Pigmented Villonodular Synovitis of the Knee: A Report of 2 Cases
Sei Kyung Chang, Jae Hwa Kim, Doo Hoe Ha, Hae Youn Kang, So Young Chong, Hyun Soo Shin
1Department of Radiation Oncology, Bundang CHA General Hospital, Pochon CHA University, Seongnam, Korea. shin0129@chamc.co.kr
2Department of Orthopedic Surgery, Bundang CHA General Hospital, Pochon CHA University, Seongnam, Korea.
3Department of Radiology, Bundang CHA General Hospital, Pochon CHA University, Seongnam, Korea.
4Department of Pathology, Bundang CHA General Hospital, Pochon CHA University, Seongnam, Korea.
5Department of Internal Medicine, Bundang CHA General Hospital, Pochon CHA University, Seongnam, Korea.
ABSTRACT
Pigmented villonodular synovitis (PVNS) is a rare proliferative disease involving synovial membranes. Natural history and etiology of PVNS are not well known. PVNS presents as localized or diffuse tumor like nodular lesion of the synovial lining of the joint and the synovial spaces adjacent to the joints. Though histologically benign, it is a very aggressive lesion, capable of bone destruction and widespread infiltration of surrounding tissues. Standard therapy is surgical resection, but due to the infiltrative growth, the recurrence rate is significantly high. After several relapses surgical treatment of diffuse PVNS becomes difficult and may require amputation of the involved limb. Radiotherapy can provide an effective treatment option for patients with large lesions or lesions which are not suitable for surgery, after incomplete resection to prevent relapses or to avoid amputation. We report 2 cases of diffuse PVNS in the knee joint treated with arthroscopic gross total synovectomy and radiotherapy.
Key Words: Diffuse pigmented villonodular synovitis, Arthroscopic gross total synovectomy, Radiotherapy
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