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J Korean Soc Ther Radiol Oncol > Volume 23(2); 2005 > Article
The Journal of the Korean Society for Therapeutic Radiology and Oncology 2005;23(2): 111-115.
Malignant Melanoma of the Vagina: A Report of 2 Cases
Ok Bae Kim, Jin Hee Kim, Young Yeon Jung, Chi Heum Cho, Tae Jin Choi
1Departments of Radiation Oncology, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea. obkim500@dsmc.or.kr
2Departments of Gynecology, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea.
3Departments of Bio-physics Medical Engineering, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea.
ABSTRACT
Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of loco- regional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approache. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.
Key Words: Malignant melanoma, Vagina, Radiation therapy
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