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J Korean Soc Ther Radiol Oncol > Volume 17(4); 1999 > Article
The Journal of the Korean Society for Therapeutic Radiology and Oncology 1999;17(4): 293-298.
Intracranial Extension of Adenoid Cystic Carcinoma of the Palate
Yoon Kyeong Oh, Keun Hong Kee
1Department of Therapeutic Radiology, Chosun University Medical College, Kwangju, Korea.
2Department of Pathology, Chosun University Medical College, Kwangju, Korea.
Intracranial involvement by adenoid cystic carcinoma (ACC) is very rare and there is no report of intracranial extension from the palate ACC in Korea. Intracranial involvement can occur in one of three ways : direct extension, perineural spread, and hematogenous spread. A case report of a 35-year-old woman with intracranial ACC is presented. Initially she had ACC of the right palate and was treated by surgery and postoperative radiation therapy. Three years and 10 months later, the paresthesia in the distribution of ophthalmic and maxillary branch of right trigeminal nerve developed without evidence of recurrence in CT scan. Ptos and total ophthalmoplegia developed sequentially and the second operation was performed. It was suggested that the tumor was spread perineurally along the trigeminal nerve into the Gasserian ganglion and then cavernous sinus and orbit. Seven years and 6 months after the first operation, direct intracranial extension into the right temporal lobe developed via sphenoid bone, sphenoid sinus and temporal bone and the third operation was done. And then lung metastasis was diagnosed. She is alive for 9 years 5 months after first operation.
Key Words: Adenoud cystic carcinoma of the palate, Intracranial extension
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