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J Korean Soc Ther Radiol > Volume 13(1); 1995 > Article
Journal of the Korean Society for Therapeutic Radiology 1995;13(1): 27-32.
Result of Radiotherapy in Non-metastatic Esophageal Cancer
Gyu Young Chai, Jeong Soon Jang, Jong Seok Lee
1Department of Therapeutic Radiology, Gyeongsang National University, College of Medicine, Gyeongsang Institute of Cancer Research, Korea.
2Department of Internal Medicine, Gyeongsang National University, College of Medicine, Gyeongsang Institute of Cancer Research, Korea.
This study was done to evaluate preliminarly the role of intraluminal brachytherapy in the radiation treatment of non-metastatic esophageal cancer.
We analyzed follow-up result of 21 patients treated at the dept. of therapeutic radiology in Gyeongsang national university hospital between April, 1989 and August, 1992. All patients received neoadjuvant chemotherapy(5-FU, Cispl-atin). Fifteen patients were treated with eternal beam alone, and in remaining 6 patients, the external beam radiotherapy followed by intraluminal brachytherapy was done.
Among 21 patients, 7 patients showed complete tumor regression after completion of radiotherapy. But 2 of these complete responder recurred at at the site of primary disease, so ultimate local control rate was 23.8%(5/21). Local control rate according to radiation treatment modality was 6.7%(1/15) in patients treated with external irradiation only, and 66.7% in patients treated with combined external irradiation and intraluminal brachytherapy. The 2 year NED survival rate was 6.6% in the former and 66.7% in the latter.
Although there should be consideration about case selection for addition of intraluminal brachytherapy, intraluminal brachytherapy may be considered as one of the method to enhance the local control probability of esophageal cancer
Key Words: High dose rate ILR, Esophageal Cancer
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