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J Korean Soc Ther Radiol > Volume 10(1); 1992 > Article
Journal of the Korean Society for Therapeutic Radiology 1992;10(1): 7-14.
Stereotactic Radiosurgery for Intracranial Tumors : Early Experience with Linear Accelerator
Chang Ok Suh, Sang Sup Chung, Sung Sil Chu, Young Soo Kim, Do Heum Yoon, Sun Ho Kim, John J Kyu Loh, Gwi Eon Kim
1Department of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center, Seoul, Korea.
2Department of Neurosurgery, Yonsei University College of Medicine, Yonsei Cancer Center, Seoul, Korea.
Between August 1988 and December 1991, 24 patients with intracranial tumors were treated with stereotactic radiosurgery(RS) using a 10 MV linear accelerator at Severance Hospital, Yonsei University College of Medicine. There were 5 meningiomas, 3 craniopharyngiomas, 9 glial tumors, 2 solitary metastases, 2 acoustic neurinomas, 2 pineal tumors, and 1 non-Hodgkin's Iymphoma. Ten patients were treated as primary treatment after diagnosis with stereotactic biopsy or neuroimaging study. Nine patients underwent RS for post-op. residual tumors and three patients as a salvage treatment for recurrence after external irradiation. Two patients received RS as a boost followed by fractionated conventional radiotherapy. Among sixteen patients who were followed more than 6 months with neuroimage, seven patients (2 meningiomas, 4 benign glial tumors, one non-Hodgkin's lymphoma) showed complete response on neuroimage after RS and nine patients showed decreased tumor size. There was no acute treatment related side reaction. Late complications include three patients with symptomatic peritumoral braid edema and one craniopharyngioma with optic chiasmal injury. Through this early experience, we conclude that stereotactically directed single high doses of irradiation to the small intracranial tumors is effective for tumor control. However, in order to define the role of radiosurgery in the management of intracranial tumors, we should get the long-term results available to demonstrate the benefits versus potential complications of this therapeutic modality.
Key Words: Stereotactic radiosurgery, Intracranial tumors
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