From March 1970 to December 1984, treatment results of 21 patients treated initially with curative surgery for adenoarcinoma of the colon and referred to the Department of Radiation Oncology, College of Medicine, Yonsei University, were analyzed retrospectively. Thirteen of 21 patients who were considered to be at high risk (i.e, stage B2 or above), received postoperative adjuvant radiation therapy. However,...

A patient with primary adenocarcinoma of Bartholin's gland is reported and the literatures relevant to this disease reviewed. Not only this disease is very rare but also primary carcinomas of Bartholin's gland are misdiagnosed as cysts or abscesses in half of the cases, leading to considerable delay in diagnosis. And so, It was wasted long time before definitive therapy. However,...

Effects of ionizing radiation alone and combined with chemotherapy on tumor growth and it's clonal specificity Monitored by changes in distribution of chromosome number were studies in A549 cell line originated from human adenocarcinoma of the lung. Radiation (300 rad, 600 rad and 900 rad) were delivered with or without 5-FU. Forty eight hours later, 57.5% of growth inhibition of...

Investigations were carried out into the time-and dose-related changes in acute skin reaction following graded single dose (20, 30 and 40 Gy) of x-ray irradiation in Wistar rats, in order to evaluate the radioprotective effect of Diethon on skin. For the duration of skin response over 1. 5 score in dose of 40 Gy, the Diethone group of 24.7 days...

Forty-four patients with brain astrocytoma and glioblastoma were treated with surgical resection and postoperative radiation from January 1980 through May 1987. Four patients were lost to follow up, and in 40 patients sruvival time was evaluable. Three year actuarial sruvival rate was 66.7% in Grade I and II astrocytoma, 30% in Grade III, and 20.4% in glioblastoma multiforme patients. The...

One hundred and ten patients with carcinoma of the nasopharynx were treated by radiation therapy in Deoartment of Therapeutic Radiology, Seoul National University Hospital between 1979 and 1985. Among these, one hundred and five patients were treated with curative intent and 5 patients with palliative aim. Excluding 16 patients who did not receive a full coarse of radiation therapy, the...

Sixty-six patients with squamous cell carcinoma of the supraglottic larynx received irradiation with curative intent between 1979 and 1985 were retrospectively analysed. All patients had a minimum follow-up of 4 years. Of the entire group consisting of 73% T3 and T4 lesions and 58% lymph node metastases, a 5-year acturial survival rate was 31.3%. A 5-year acturial survival rates for stage...

From Feb. 1985 to Feb. 1988, 76 patients with squamous cell carcinoma of the lung treated at the Department of Therapeutic Radiology in Kyungpook National University Hospital were available for the analysis of this study. All patients received radiation of 4000c0y-6600c0y with curative aim. The overall rate of complete response was 25.0% and partial response was 52.6%. The complete and...

Cervix cancer is the most common female cancer in Korea. In spite of their relatively local invasive tendency, still 44% of patient will develop recurrent cancer This result suggests that more aggressive local treatment may increase the cure rate but increased complication risk also cannot be avoidable. Various institutions proposed different treatment regimen, but recommended dose were about 4500 cGy...

Invasive carcinoma of the cervix during the pregnancy is relatively uncommon , It must be considered fetal viability, tumor control as well. If the carcinoma is diagnosed in the first or second trimester, treatment should be undertaken immediately. At the third trimester, treatment should be undertaken until the fetus is viable.

This study, involving thirty-two patients with carcinoma of uterine cervix treated by high dose rate intracavitary irradiation using a remotely controlled afterloading system, compares the doss at point A and B with the Curie-minutes prescription. A linear least-square regression analysis was used to compare the two sets of date. Correlation coefficients between doses at points A and B arid the...

Dosimetry based on electron spin resonance(ESR) analysis of radiation induced free radicals in amino acids is relevant to biological dosimetry applications. Alanine detectors are without walls and are tissue equivalent. Therefore, alanine ESR dosimetry looks promising for use in the therapy level. The dose range of the alanine/ESR dosimetry system can be extended down to l Gy. In a water phantom...

Several combinations of measuring devices and phantoms were studied to measure electron beams. Silicon PN junction diode was used to find the dependence of depth dose profile on field size on axis of electron beam Depths of 50, 80 and 90% doses increased with the field size for small fields. For some larger fields, they were nearly constant. The smallest...

The treatment planning and dosimetry of small fields for stereotactic radiosurgery with 10 MV x-ray isocentrically mounted linear accelerator is presented. Special consideration in this study was given to the variation of absorbed dose with field size, the central axis percent depth doses and the combined moving beam dose distributon. The collimator scatter correction factors of small fields (1x1~3x3 cm2) were...

The inclusion of air filled cavities in treatment fields creates a potential dosimetric problem due to the rebuildup phenomenon near the air-tissue interface using a simulated phantom, such as air gap, air cylinder, and air cavity, the amount of rebuldup along the various field sizes and air cavity dimensions was measured. The results are as follows. 1. As the field size...

A radiation beam incident on an irregular or sloping surface produces the non-uniformity of absorbed dose. The use of a tissue compensator can partially correct this dose inhomogeneity. The tissue compensator is designed based on the patient's three dimensional contour. After required compensator thickness was determined according to tissue deficit at 25 cmx 25 cm field size, 10 cm depth...

Three-dimension paraffin compensator was designed to construct the tissue equivalent compensator for irregular body contours and obiliques beam incidence. The ratio of compensator thickness to tissue deficit was depended on field size, depth and air gap because the scattered dose loss. The ratio of compensator-tissue was optimized 0.79, 0.73, 0.61 and 0.50 in 6MV x-rays as function of field size...