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Review Articles
The effects of high-dose radiation therapy on bone: a scoping review
Lawrence Berk
Radiat Oncol J.
2024;42(2):95-103. Published online February 27, 2024
Web of Science 3
Cited By 7
Purpose:
This scoping review presents the preclinical and clinical data on the effects of high-dose radiation therapy (RT) on bone structure and function. Materials and Method: An extensive PubMed search was performed for the relevant questions. The data were then synthesized into a comprehensive summary of the available relevant in-vitro, preclinical and clinical literature. Results: In-vitro studies of high-dose RT on cell...
DOI:
https://doi.org/10.3857/roj.2023.00969
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Research progress and treatment of radiation enteritis and gut microbiota
Huiwen Ren
, Qi Wu
, Zhiqiang Sun
, Mingming Fang
, Jun Liu
, Judong Luo
Radiat Oncol J.
2023;41(2):61-68. Published online June 28, 2023
Web of Science 9
Cited By 11
Radiation enteritis is a kind of intestinal radiation injury in patients with pelvic and retroperitoneal malignancies after radiotherapy, and its occurrence and development process are very complicated. At present, studies have confirmed that intestinal microecological imbalance is an important factor in the formation of this disease. Abdominal radiation causes changes in the composition of the flora and a decrease in...
DOI:
https://doi.org/10.3857/roj.2023.00346
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A practical review of watch-and-wait approach in rectal cancer
Hwa Kyung Byun
, Woong Sub Koom
Radiat Oncol J.
2023;41(1):4-11. Published online March 28, 2023
Web of Science 10
Cited By 11
Rectal resection surgery after neoadjuvant treatment has been the mainstay treatment of locally advanced rectal cancer. However, functional outcomes and quality of life after radical resection of the rectum remain suboptimal. The excellent oncologic outcomes in patients who achieved pathologic complete response after neoadjuvant treatment questioned the need for radical surgery. The watch-and-wait approach is a noninvasive therapeutic alternative for...
DOI:
https://doi.org/10.3857/roj.2023.00038
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Original Articles
The first Korean carbon-ion radiation therapy facility: current status of the Heavy-ion Therapy Center at the Yonsei Cancer Center
Min Cheol Han
, Seo Hee Choi
, Chae-Seon Hong
, Yong Bae Kim
, Woong Sub Koom
, Jin Sung Kim
, Jaeho Cho
, Chan Woo Wee
, Changhwan Kim
, Jong Won Park
, Soorim Han
, Heejeong Lee
, Hong In Yoon
, Ik Jae Lee
, Ki Chang Keum
Radiat Oncol J.
2024;42(4):295-307. Published online December 20, 2024
Purpose:
This report offers a detailed examination of the inception and current state of the Heavy-ion Therapy Center (HITC) at the Yonsei Cancer Center (YCC), setting it apart as the world’s first center equipped with a fixed beam and two superconducting gantries for carbon-ion radiation therapy (CIRT). Materials and Methods: Preparations for CIRT at YCC began in 2013; accordingly, this...
DOI:
https://doi.org/10.3857/roj.2024.00206
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Developing prompts from large language model for extracting clinical information from pathology and ultrasound reports in breast cancer
Hyeon Seok Choi
, Jun Yeong Song
, Kyung Hwan Shin
, Ji Hyun Chang
, Bum-Sup Jang
Radiat Oncol J.
2023;41(3):209-216. Published online September 21, 2023
Web of Science 49
Cited By 57
Purpose:
We aimed to evaluate the time and cost of developing prompts using large language model (LLM), tailored to extract clinical factors in breast cancer patients and their accuracy. Materials and Methods: We collected data from reports of surgical pathology and ultrasound from breast cancer patients who underwent radiotherapy from 2020 to 2022. We extracted the information using the Generative Pre-trained...
DOI:
https://doi.org/10.3857/roj.2023.00633
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Supplementary Material
Review Article
Exploring the past, present, and future of postoperative radiotherapy for N2 stage non-small cell lung cancer
Byoung Hyuck Kim
, Jae Sik Kim
, Hak Jae Kim
Radiat Oncol J.
2023;41(3):144-153. Published online August 23, 2023
Web of Science 4
Cited By 5
Despite conventionally applied postoperative radiotherapy (PORT) in pathological N2 (pN2) stage non-small cell lung cancer (NSCLC) considering high locoregional recurrence, its survival benefit has been a continuous topic of debate. Although several randomized clinical trials have been conducted, many of them have been withdrawn or analyzed without statistical significance due to slow accrual, making it difficult to determine the efficacy...
DOI:
https://doi.org/10.3857/roj.2023.00430
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Original Articles
Proton therapy for reducing heart and cardiac substructure doses in Indian breast cancer patients
Sapna Nangia
, Nagarjuna Burela
, M. P. Noufal
, Kartikeswar Patro
, Manoj Gulabrao Wakde
, Dayanada S. Sharma
Radiat Oncol J.
2023;41(2):69-80. Published online June 1, 2023
Web of Science 6
Cited By 6
Purpose:
Indians have a higher incidence of cardiovascular diseases, often at a younger age, than other ethnic groups. This higher baseline risk requires consideration when assessing additional cardiac morbidity of breast cancer treatment. Superior cardiac sparing is a critical dosimetric advantage of proton therapy in breast cancer radiotherapy. We report here the heart and cardiac-substructure doses and early toxicities in...
DOI:
https://doi.org/10.3857/roj.2023.00073
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Review Article
Evidence-based clinical recommendations for hypofractionated radiotherapy: exploring efficacy and safety - Part 3. Genitourinary and gynecological cancers
Gyu Sang Yoo
, Soo-Yoon Sung
, Jin Ho Song
, Byoung Hyuck Kim
, Yoo-Kang Kwak
, Kyung Su Kim
, Hwa Kyung Byun
, Yeon-Sil Kim
, Yeon Joo Kim
Radiat Oncol J.
2024;42(3):171-180. Published online July 8, 2024
Hypofractionated radiotherapy (RT) has become a trend in the modern era, as advances in RT techniques, including intensity-modulated RT and image-guided RT, enable the precise and safe delivery of high-dose radiation. Hypofractionated RT offers convenience and can reduce the financial burden on patients by decreasing the number of fractions. Furthermore, hypofractionated RT is potentially more beneficial for tumors with a...
DOI:
https://doi.org/10.3857/roj.2023.01046
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Case Reports
Implementing high-dose rate surface mould brachytherapy for carcinoma of eyelid: a practical approach and weekly review
Kanhu Charan Patro
, Ajitesh Avinash
, Arya Banidutta
, Chitta Ranjan Kundu
, Partha Sarathi Bhattacharya
, Venkata Krishna Reddy Pilaka
, Mrutyunjayarao Muvvala
, Ayyalasomayajula Anil Kumar
, Srinu Aketi
, Keerthiga Karthikeyan
, Bhargava Krishna Madasu
, Dona Treesa Vincent
Radiat Oncol J.
2024;42(2):154-159. Published online March 4, 2024
Surface mould brachytherapy is a conformal radiotherapy technique that can deliver high dose to the target while sparing nearby normal structures, Here, we aim to describe the procedurals details for high-dose rate (HDR) surface mould brachytherapy in sebaceous carcinoma of eyelid in a 54-year old lady. She was hesitant for surgery and any form of invasive intervention like interstitial brachytherapy....
DOI:
https://doi.org/10.3857/roj.2023.00682
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Original Articles
Validation of Combs prognostic scoring system in Indian recurrent glioma patients treated with re-radiation
Debnarayan Dutta
, Meenu Jose
, Sruthi Kalavagunta
, Ajay Sasidharan
, Haridas Nair
, Annex H. Edappattu
Radiat Oncol J.
2024;42(1):32-42. Published online January 23, 2024
Purpose:
Retrospective audit of recurrent glioma patients treated by different fractionation schedules and to validate the modified Combs prognostic score in Indian patient cohort. Material and Methods: Between Jan 2009 and June 2022, 66 recurrent gliomas patients treated with standard adjuvant treatment—radiation (RT) ± temozolomide (chemotherapy)—and re-treated with RT (±chemotherapy) were categorized as per modified Combs prognostic criteria and outcomes were...
DOI:
https://doi.org/10.3857/roj.2023.00542
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Analysis of risk factors for disease progression after salvage radiation therapy with androgen deprivation therapy in prostate cancer patients who have prostate-specific antigen persistence after radical prostatectomy
Kyeonghyo Lee
, Dongchan Kim
, Jiho Nam
, Dahl Park
, Wontaek Kim
, Jihyeon Joo
, Hosang Jeon
, Yongkan Ki
, Donghyun Kim
Radiat Oncol J.
2024;42(2):124-129. Published online June 5, 2024
Purpose:
To assess risk factors of disease progression after salvage radiation therapy (SRT) with androgen deprivation therapy (ADT) in case of prostate-specific antigen (PSA) persistence after radical prostatectomy (RP). Materials and Methods: We analyzed 57 patients who received SRT with ADT between 2013 and 2019 due to PSA persistence after RP. The endpoint was disease progression defined by biochemical recurrence or...
DOI:
https://doi.org/10.3857/roj.2023.00962
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Case Reports
A case of cetuximab-induced radiation recall skin dermatitis and review of the literature
Rachel A. Sabol
, Akshat M. Patel
, Ali Sabbagh
, Chyrstal Wilson
, Florence Yuen
, Paul Lindenfeld
, Rahul Aggarwal
, Benjamin Breyer
, Osama Mohamad
Radiat Oncol J.
2023;41(4):292-296. Published online September 14, 2023
Web of Science 1
Cited By 2
Radiation recall presents as an acute inflammatory reaction triggered by systemic therapy, usually chemotherapy, and is typically limited to an area that was previously irradiated. Radiation recall reactions are generally self-limiting and most commonly occur in the skin. Many systemic agents have been described to elicit a radiation recall reaction, but the exact pathogenesis is largely unknown. Here, we describe...
DOI:
https://doi.org/10.3857/roj.2023.00577
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Original Articles
Comparison between 1-week and 2-week palliative radiotherapy courses for superior vena cava syndrome
Jongmoo Park
, Jeong Eun Lee
Radiat Oncol J.
2023;41(3):178-185. Published online September 25, 2023
Web of Science 4
Cited By 3
Purpose:
The aim of this study was to evaluate the effectiveness of palliative radiation therapy (RT) for superior vena cava (SVC) syndrome from lung cancer and to compare the 2-week and 1-week schedules. Materials and Methods: A retrospective study was conducted on lung cancer patients with palliative RT for SVC syndrome. Patients received 30 Gy in 10 fractions (2-week group) or...
DOI:
https://doi.org/10.3857/roj.2023.00626
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Supplementary Material
Editorial
Hypofractionated radiation therapy for head and neck cancers in the era of intensity-modulated radiation therapy
Keun-Yong Eom
Radiat Oncol J.
2024;42(1):1-3. Published online March 26, 2024
Cited By 1
DOI:
https://doi.org/10.3857/roj.2024.00178
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Original Articles
Safety and efficacy of salvage conventional re-irradiation following stereotactic radiosurgery for spine metastases
Marcus A. Florez
, Brian De
, Bhavana V. Chapman
, Anussara Prayongrat
, Jonathan G. Thomas
, Thomas H. Beckham
, Chenyang Wang
, Debra N. Yeboa
, Andrew J. Bishop
, Tina Briere
, Behrang Amini
, Jing Li
, Claudio E. Tatsui
, Laurence D. Rhines
, Amol J. Ghia
Radiat Oncol J.
2023;41(1):12-22. Published online March 14, 2023
Web of Science 3
Cited By 2
Purpose:
There has been limited work assessing the use of re-irradiation (re-RT) for local failure following stereotactic spinal radiosurgery (SSRS). We reviewed our institutional experience of conventionally-fractionated external beam radiation (cEBRT) for salvage therapy following SSRS local failure. Materials and Methods: We performed a retrospective review of 54 patients that underwent salvage conventional re-RT at previously SSRS-treated sites. Local control...
DOI:
https://doi.org/10.3857/roj.2022.00353
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