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Table of Contents | June, 2016  Vol. 34  No.2 Previous Issue | Next Issue | Archive
In this issue:



Review Article
Hypofractionated whole breast irradiation: new standard in early breast cancer after breast-conserving surgery
Kyung Su Kim, Kyung Hwan Shin, Noorie Choi, Sea-Won Lee
Radiat Oncol J. 2016;34(2):81-87.   Published online June 17, 2016
Hypofractionated whole breast irradiation (HF-WBI) has been proved effective and safe and even better for late or acute radiation toxicity for early breast cancer. Moreover, it improves patient convenience, quality of life and is expected to be advantageous in the medical care system by reducing overall cost. In this review, we examined key randomized trials of HF-WBI, focusing on adequate...
Original Articles
Clinical Investigations
The clinical utilization of radiation therapy in Korea between 2009 and 2013
Jin-Kyu Kang, Mi-Sook Kim, Won-Il Jang, Young Seok Seo, Hee Jin Kim, Chul Koo Cho, Hyung Jun Yoo, Eun Kyung Paik, Yu Jin Cha, Hyun Jin Song
Radiat Oncol J. 2016;34(2):88-95.   Published online June 30, 2016

Purpose: The purpose of this study was to estimate the clinical utilization of radiation therapy (RT) in Korea between 2009 and 2013. Materials and Methods: We analyzed open claims data from the Health Insurance Review and Assessment Service. The subjects were patients who had diagnostic codes C00-C97 or D00-D48 according to the 10th revision of the International Classification of Diseases, with...
Preoperative chemoradiation for locally advanced rectal cancer: comparison of three radiation dose and fractionation schedules
Shin-Hyung Park, Jae-Chul Kim
Radiat Oncol J. 2016;34(2):96-105.   Published online June 17, 2016

Purpose: The standard radiation dose for patients with locally rectal cancer treated with preoperative chemoradiotherapy is 45–50 Gy in 25–28 fractions. We aimed to assess whether a difference exists within this dose fractionation range. Materials and Methods: A retrospective analysis was performed to compare three dose fractionation schedules. Patients received 50 Gy in 25 fractions (group A), 50.4 Gy in 28...
Predictors of pathologic complete response after preoperative concurrent chemoradiotherapy of rectal cancer: a single center experience
Euncheol Choi, Jin Hee Kim, Ok Bae Kim, Mi Young Kim, Young Ki Oh, Sung Gyu Baek
Radiat Oncol J. 2016;34(2):106-112.   Published online June 17, 2016

Purpose: To identify possible predictors of pathologic complete response (pCR) of rectal cancer after preoperative concurrent chemoradiotherapy (CCRT). Materials and Methods: We conducted a retrospective review of 53 patients with rectal cancer who underwent preoperative CCRT followed by radical surgery at a single center between January 2007 and December 2012. The median radiotherapy dose to the pelvis was 54.0 Gy (range,...
Association between obesity and local control of advanced rectal cancer after combined surgery and radiotherapy
Yunseon Choi, Yun-Han Lee, Sung Kwang Park, Heunglae Cho, Ki Jung Ahn
Radiat Oncol J. 2016;34(2):113-120.   Published online June 17, 2016

Purpose: The association between metabolism and cancer has been recently emphasized. This study aimed to find the prognostic significance of obesity in advanced stage rectal cancer patients treated with surgery and radiotherapy (RT). Materials and Methods: We retrospectively reviewed the medical records of 111 patients who were treated with combined surgery and RT for clinical stage 2–3 (T3 or N+) rectal...
Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma
Mi Young Kim, Jin Hee Kim, Young Kee Oh, El Kim
Radiat Oncol J. 2016;34(2):121-127.   Published online June 17, 2016

Purpose: To investigate treatment outcome and long term complication after surgery and radiotherapy (RT) for pituitary adenoma. Materials and Methods: From 1990 to 2009, 73 patients with surgery and RT for pituitary adenoma were analyzed in this study. Median age was 51 years (range, 25 to 71 years). Median tumor size was 3 cm (range, 1 to 5 cm) with suprasellar...
Treatment outcome of radiation therapy and concurrent targeted molecular therapy in spinal metastasis from renal cell carcinoma
Sangjoon Park, Kyung Hwan Kim, Woo Joong Rhee, Jeongshim Lee, Yeona Cho, Woong Sub Koom
Radiat Oncol J. 2016;34(2):128-134.   Published online June 17, 2016

Purpose: To evaluate the clinical outcomes of patients who underwent radiation therapy with or without targeted molecular therapy for the treatment of spinal metastasis from renal cell carcinoma (RCC). Materials and Methods: A total of 28 spinal metastatic lesions from RCC patients treated with radiotherapy between June 2009 and June 2015 were retrospectively reviewed. Thirteen lesions were treated concurrently with targeted...
Art therapy using famous painting appreciation maintains fatigue levels during radiotherapy in cancer patients
Woong Sub Koom, Mi Yeon Choi, Jeongshim Lee, Eun Jung Park, Ju Hye Kim, Sun-Hyun Kim, Yong Bae Kim
Radiat Oncol J. 2016;34(2):135-144.   Published online June 17, 2016

Purpose: The purpose of this study was to evaluate the efficacy of art therapy to control fatigue in cancer patients during course of radiotherapy and its impact on quality of life (QoL). Materials and Methods: Fifty cancer patients receiving radiotherapy received weekly art therapy sessions using famous painting appreciation. Fatigue and QoL were assessed using the Brief Fatigue Inventory (BFI) Scale...
Physics Contributions
Dosimetric comparison of axilla and groin radiotherapy techniques for high-risk and locally advanced skin cancer
Malcolm D. Mattes, Ying Zhou, Sean L. Berry, Christopher A. Barker
Radiat Oncol J. 2016;34(2):145-155.   Published online June 17, 2016

Purpose: Radiation therapy targeting axilla and groin lymph nodes improves regional disease control in locally advanced and high-risk skin cancers. However, trials generally used conventional two-dimensional radiotherapy (2D-RT), contributing towards relatively high rates of side effects from treatment. The goal of this study is to determine if three-dimensional conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT), or volumetric-modulated arc therapy...
Case Report
Delayed radiation-induced inflammation accompanying a marked carbohydrate antigen 19-9 elevation in a patient with resected pancreatic cancer
Malcolm D. Mattes, Jon S. Cardinal, Geraldine M. Jacobson
Radiat Oncol J. 2016;34(2):156-159.   Published online June 17, 2016
Although carbohydrate antigen (CA) 19-9 is a useful tumor marker for pancreatic cancer, it can also become elevated from a variety of benign and malignant conditions. Herein we describe an unusual presentation of elevated CA 19-9 in an asymptomatic patient who had previously undergone adjuvant chemotherapy and radiation therapy for resected early stage pancreatic cancer. The rise in CA 19-9...
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