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- In Vitro
- The Use of MTT Assay, In Vitro and Ex Vivo, to Predict the adiosensitivity of Colorectal Cancer
- Ji Eun Kim, Mi Sook Kim, Chang Mo Kang, Jong Il Kim, Hye Kyung Shin, Chul Won Choi, Young Seok Seo, Young Hoon Ji
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Radiat Oncol J. 2008;26(3):166-172.
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PURPOSE: The measurement of radiosensitivity of individuals is useful in radiation therapy. Unfortunately, the measurement of radiation survival using a clonogenic assay, which is the established standard, can be difficult and time consuming. The aim of this study is to compare radiosensitivity results obtained from the MTT and clonogenic assays, and to evaluate whether the MTT assay can be used... |
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- Original Articles
- Postoperative External Beam Radiotherapy for Retroperitoneal Soft Tissue Sarcoma
- Na Young Jang, Il Han Kim, Jin Hwa Choi, Charn Il Park
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Radiat Oncol J. 2008;26(3):135-141.
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PURPOSE: To evaluate the clinical outcomes and prognostic factors in retroperitoneal soft tissue sarcomas treated by postoperative radiotherapy.
MATERIALS AND METHODS: The records of 23 patients with retroperitoneal soft tissue sarcomas, who underwent postoperative radiotherapy between 1985 and 2003, were analyzed. The median follow-up period was 77 months (range, 8~240 months). A total of 21 patients presented with primary disease, and... |
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- Results of Breast Conserving Surgery and Subsequent Postoperative Radiotherapy for Cases of Breast Cancer
- Eui Kyu Chie, Kyubo Kim, Jin Hwa Choi, Na Young Jang, Wonshik Han, Dong Young Noh, Seock Ah Im, Tae You Kim, Yung Jue Bang, Sung Whan Ha
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Radiat Oncol J. 2008;26(3):142-148.
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PURPOSE: We analyzed the treatment outcomes and prognostic factors of breast conserving surgery, followed by postoperative radiotherapy.
MATERIALS AND METHODS: A total of 424 breast cancer patients treated with breast conserving surgery and postoperative radiotherapy between February 1992 and January 2001 were retrospectively analyzed. A quadrantectomy and axillary lymph node dissection was performed in 396 patients. A total of 302 patients... |
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- The Results and Prognostic Factors of Postoperative Radiation Therapy in the Early Stages of Endometrial Cancer
- Kyung Ja Lee
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Radiat Oncol J. 2008;26(3):149-159.
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PURPOSE: To evaluate the results and prognostic factors for postoperative adjuvant radiation therapy in patients at stages I and II of endometrial cancer.
MATERIALS AND METHODS: Between January 1991 and December 2006, 35 patients with FIGO stages I and II disease, who received adjuvant radiation therapy following surgery for endometrial cancer at Ewha Womans University Hospital, were enrolled in this study.... |
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- Concurrent Chemoradiotherapy with Biweekly Gemcitabine and Cisplatin in Patients with Locally Advanced Non-small Cell Lung Cancer
- Chul Ho Oak, Ja Kyung Kim, Lee La Jang, Dae Sung Moon, Tae Won Jang, Maan Hong Jung, Sung Whan Cho, Tae Sig Jeung
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Radiat Oncol J. 2008;26(3):160-165.
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PURPOSE: In cases of locally advanced non-small cell lung cancer (NSCLC), concurrent chemoradiotherapy (CCRT) is the leading therapeutic modality. However, much controversy exists about the chemotherapeutic regimens and radiation methods.
MATERIALS AND METHODS: During concurrent chemoradiotherapy, three or four cycles of gemcitabine (500 mg/m2) and cisplatin (30 mg/m2) were administered every two weeks while 50.4 Gy of irradiation was administered in... |
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- Lack of EGCG Effects on Radiation-Induced Apoptosis of Mice Splenocytes
- Seong Soon Jang, Heui Kwan Lee
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Radiat Oncol J. 2008;26(3):173-180.
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PURPOSE: The modification of radiation-induced apoptosis by EGCG, known as antioxidants or oxidants, was studied in mice spleens irradiated with a lethal dose.
MATERIALS AND METHODS: Male C57BL/6 mice were divided into control, irradiation-only, and EGCG (100 mg/kg i.p. 1 h before irradiation) pretreatment groups. The mice were irradiated with a single whole-body dose of 7 Gy. The apoptosis in the... |
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- Efficacy of a Respiratory Training System on the Regularity of Breathing
- Eunhyuk Shin, Hee Chul Park, Youngyih Han, Sang Gyu Ju, Jung Suk Shin, Yong Chan Ahn
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Radiat Oncol J. 2008;26(3):181-188.
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PURPOSE: In order to enhance the efficiency of respiratory gated 4-dimensional radiation therapy for more regular and stable respiratory period and amplitude, a respiration training system was designed, and its efficacy was evaluated.
MATERIALS AND METHODS: The experiment was designed to measure the difference in respiration regularity following the use of a training system. A total of 11 subjects (9 volunteers... |
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- Evaluation of a Water-based Bolus Device for Radiotherapy to the Extremities in Kaposi's Sarcoma Patients
- Seung Kwon Ahn, Yong Bae Kim, Ik Jae Lee, Tae Soo Song, Dong Min Son, Yung Jae Jang, Jung Hee Cho, Joo Ho Kim, Dong Wook Kim, Jae Ho Cho, Chang Ok Suh
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Radiat Oncol J. 2008;26(3):189-194.
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PURPOSE: We designed a water-based bolus device for radiation therapy in Kaposi's sarcoma. This study evaluated the usefulness of this new device and compared it with the currently used rice-based bolus.
MATERIALS AND METHODS: We fashioned a polystyrene box and cut a hole in order to insert patient's extremities while the patient was in the supine position. We used a vacuum-vinyl... |
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