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Table of Contents | , 1988  Vol. 6  No.2 Previous Issue | Next Issue | Archive
In this issue:


Original Articles
A Study on the Radiation Tumor Control Microscopic Tumors of the C3Hf/Sed Mouse Spontaneous Fibrosarcoma
Sung Whan Ha, Herman D Suit
Radiat Oncol J. 1988;6(2):151-154.
To answer the question whether last clonogenic cell should be eradicated for the tumor to be controlled, radiation tumor control study was performed using microscopic tumors of variable sizes ranging from 101 to 105 tumor cells. TCD50's estimated from experimental data were 14.8, 27.1, 42.4, 49.9 and 65.5 gy for 10(1), 10(2), 10(3), 10(4) and 10(5) tumor cells, respectively. Theoretical calculations,...
Effect of Step-up and Step-down Hyperthermia on Skin of Mice
Ihl Bohng Choi, Choon Yul Kim, Yong Whee Bahk
Radiat Oncol J. 1988;6(2):155-162.
The usefulness of hypertemie for cancer therapy have well been established. The purpose of the present investigation was to ascess the effect of step-up (42 degrees C -> 44 degrees C sequence ) and step-down (44 degrees C -> 42 degrees C sequence) heating on the skin of the hind foot of the mouse. Hyperthermic treatments were given by immersion...
Radiotherapy Results of Brain Astrocytoma and glioblastoma Multiforme
Doo Ho Choi, Il Han Kim, Sung Whan Ha, Je Geun Chi
Radiat Oncol J. 1988;6(2):163-168.
A retrospective analysis was performed on 49 patients with astrocytoma of glioblastoma multiforme of brain who received postoperative radiotherapy in the period between February 1979 and December 1985. Fourteen patients had grade I astrocytoma, 11 patients grade II, 14 patients grade III, and 10 patients glioblastoma multiforme. Three year actuarial surival rates were 85.7%, 44.6% and 23.1% for grade I,II,...
Radiation Therapy of Suprasellar gern Cell Tumors
Woo Yoon Park, Doo Ho Choi, Eun Kyung Choi, Il Han Kim, Sung Whan Ha, Charn Il Park
Radiat Oncol J. 1988;6(2):169-176.
A retrospective study was performed on 15 patients with suprasellar germ cell tumors treated by megavoltage external beam irradiation between Feb. 1979 and Dec. 1985. Follow-up period of survivors was 30 to 91 moths. Histologic diagnosis was obtained before radiation therapy in 10 patients (9 germinomas and 1 mixed). Five patients were treated without histologic verification. In 9 patients with...
Radiotherapy Results of pineal Tumors
Kyu Young Chai, Woo Yoon Park, Doo Ho Choi, Woong Ki Chung, Il Han Kim, Sung Whan Ha
Radiat Oncol J. 1988;6(2):177-182.
A retrospective analysis was performed on 23 patients with pineal region tumors treated with radiation from 1979 through 1985 at the Department of Therapeutic Radiology, Seoul National University Hospital, Histologic confirmation was done in only one case by surgical removal, and in the remaining 22 patients, the diagnosis was based on clinical and radiological findings. The radiation volume was the...
Medulloblastoma: Radiotherapy Result with Emphasis on Radiation Dose and Methods of Craniospinal Treatiment
Il Han Kim, Sung Whan Ha, Charn Il Park, Byung Kyu Cho
Radiat Oncol J. 1988;6(2):183-194.
Twenty five patients with histologically proven medulloblastoma received craniospinal radiotherapy (CSRT) at the Seoul National University Hospital from 1979 to 1984. The extent of tumor removal was biopsy only in 2 patients, partial in 18, and near total in 5. With orthogonal technique of CSRT, mainly 55 gy was delivered to the posterior fossa(PF). 40gy to whole brain (WB), and 30...
Postoperative Radiation Therapy in Non-Sma-Cell Lung Cancer
Charn Il park, Jong Hoon Kim, Joo Hyun Kim
Radiat Oncol J. 1988;6(2):195-202.
Sixty patients with proven lung cancer were retrospectively studied to determine whether postoperative radiation therapy improves survival. Patterns of treatment failure and 5 year survival were assessed according to extent of tumor spread, histology, type of operation, positive resection margin and radiation dose. Of the 60 patients, excluding 5 patients who received incomplete treatment of poor pulmonary function, 55 patients...
Radiotherapy in Locoregional Recurrent Breast Carcinoma
Sung Whan Ha, Mi Gyoung Yang, Woong Ki Chung, Charn Il Park, Yung Jue Bang, Noe Kyung Kim, Kuk Jin Choe
Radiat Oncol J. 1988;6(2):203-210.
Thirty eight women with recurrent breast carcinoma involving chest wall and/or regional lymph nodes after surgery with or without systemic therapy were treated with radiation between 1979 and 1986. Among them, 5 patients were excluded from analysis because of incomplete treatment. The median follow up of survivors was 30 months (randged 1-79 months). Fifteen (45%) patients had their disease confined...
Result of Radiotherapy for Esophagus Cancer
Taesig Jung, Changwoo Moon, Hayong Yum, Chilyong Yang
Radiat Oncol J. 1988;6(2):211-226.
Among 165 patients of esophagus cancer treated by either radiation alone or postoperative radiation, median survival period was 6.6 months, 16% 3 years and 8% 5 years crude survival in biphasic plotting of survival curve semilogarithmically all nonresponder died within one year regardless of treatments and in responder each 1, 2, 3 years survival rate was 80%, 70%, 60% in...
The Result of Radiotherapy in Esophageal Cancer
Charn Il Park, Eun Kyung Choi, Woong Ki Chung, Yung Jue Bang, Noe Kyeong Kim
Radiat Oncol J. 1988;6(2):227-234.
During the period between March 1979 and August 1986, 177 patients with carcinoma of the esophagus were treated with radiotherapy in the Department of Therapeutic Radiology, SNUH. Among these, 25 patients who had incomplete treatment were excluded. So a retrospective analysis was undertaken of 152 patients who were treated by curative radiotherapy. More than 80% showed response: Complete remission (22%),...
The Role of Radiotherapy in Management of Rectal Cancer
John Kyu Loh, Chang Geol Lee, Jin Sil Seong, Soo Kon Kim, Kyung Ran Park, Chang Ok Suh, Gwi Eon Kim
Radiat Oncol J. 1988;6(2):235-246.
A total of 93 patients with rectal cancer treated with radiotherapy at department of Radiation Oncology, Yonsei University College of Medicine, Yonsei Cancer Center between January 1974 and December 1983 are retrospectively analysed. The patients are divided into three groups as follows: I. Postoperative radiotherapy, II. Pstoperative recurrent, III. Unresectable or Inoperable group. In postoperative radiotherapy group, overall 5 year survival rate is...
Total Body Irradiation in Leukemia: Preliminary Report
Hong Seok Jang, Su Mi Chung, Ihl Bohng Choi, Choon Yul Kim, Yong Whee Bahk, Choon Choo Kim, Dong Jip Kim, Jae Soo Lee
Radiat Oncol J. 1988;6(2):247-252.
Total body irradiation has been applied to treat acute leukemia and chronic granulocytic leukemia. 20 patients with acute leukemia or chronic granulocytic leukemia were treated with total body irradiation using 6 MV linear accelerator before bone marrow transplantation at the Division of Therapeutic Radiology, department of Radiology, St. Mary's Hospital, catholic University Medical College from August 1987 to September 1988....
The Radiation Effect on Peripheral Blood Cell
Tae June Lee, Hyoung Cheol Kwon, Jung Soo Kim, Sun Kyun Im, Ki Chul Choi
Radiat Oncol J. 1988;6(2):253-258.
To evaluate radiation effect on the hematopoietic system, we analyzed 44 patients who were treated with conventionally fractionated radiation therapy (RT) at Chonbuk National University Hospital. According to the treatment sites, we classified them into three groups: group I as head and neck, group II as thorax, and group III as pelvis. White blood cell, lymphocyte, platelet and hemoglobin were...
The Modified Method of Splenic Irradiation
Su Mi Chung, Hong Seok Jang, Ihl Bohng Choi, Choon Yul Kim, Yong Whee Bahk
Radiat Oncol J. 1988;6(2):259-262.
Splenic irradiation in chronic myelogenous leukemia is reserved for patients who have painful splenomegaly despite chemotherapy and/or inoperable splenomegaly because of huge size. The role of splenic irradiation is diminution of painful splenomegaly and indirect effect of splenic irradiation on unirradiated hematopoietic and lymphoreticular tissue such as reduction of leukocyte count and increase of hemoglobin level. We report on a...
A Study on Dose Distribution around Fletcher-Suit Colpostat Containing 137Cs Source
Wee Saing Kang
Radiat Oncol J. 1988;6(2):263-268.
This paper presents dose distributions in water around Fletcher-Suit colpostat containing 137Cs tube, and shielding effect of internal lead shield. Using ready packed film, author measured dose distribution in water around the colpostat containing cesium source. Nine sheets of films on one side of the colpostat are packed with acryl frames cut out so as to fill water, and irradiated...
Stereotactic Radiotherapy by 6MV Linear Accelerator
Yoon Kyeong Oho, Mi Hee Kim, Hak Jun Gil, Sei Chul Yoon, Jae Moon Lee, Kyu Ho Choi, Kyung Sub Shinn, Yong Whee Bahk, Moon Chan Kim, Joon Ki Kang, Jin Un Song
Radiat Oncol J. 1988;6(2):269-276.
Eight patients with intracranial tumors or arteriovenous malformation (AVM)s which were less than 3 cm in diameter were treated by a technique of stereotactic radiotherapy during the 4 months period from July 1988 through October 1988 at the Division of Radiation Therapy, Kang-Nam St. Mary's Hospital, Catholic University Medical College. The patients were diagnosed as AVMs in 3 cases, acoustic neurinoma,...
Ir-192 Brachytherapy Planning of Brain Tumor
Tae Kin Choi, Jeong Ho Park, Ok Bae Kim, Soo Ji Suh
Radiat Oncol J. 1988;6(2):277-282.
Although widely used in external beam treatment planning, computed tomography scans are infrequent in incranial tumors by implanting of Radioactive isotope. This incranial brachytherapy has only become possible by using CT scans and stereotaxic operation methods. The coincidence of single source and tumor axes in brachytherapy is very important to determine the therapeutic dosages. Eventhough using the CT scan, according...
Intracavitary Irradiation of Locally Advanced Recurrent Adenocarcinoma of Rectum Along the Fistula tract
Kyeong Ae Kim, Sung Kyu Kim, Sei One Shin, Myung Se Kim, Sun Kyuo Song, Min Chul Shim, Koing Bo Kwun
Radiat Oncol J. 1988;6(2):289-294.
Radiation therapy has been used as adjuvant therapy or primary treatment for inoperable, remnant or recurrent cancer. Many authors reported good palliation effect by external irradiation or interstitial therapy, but the report of intracavitary irradiation for recurrent, inoperable rectal cancer is very rare. We experienced a case of recurrent adenocarcinoma of rectum along fistula tract after laparotomy and postoperative radiotherapy...
Case Reports
Radical Radiotherapy with Lympectomy (Wide excisional biopsy) for Early Breast Cancer: A Case Report and Review of Literature
Won Young Oh, In Soon Whang
Radiat Oncol J. 1988;6(2):283-288.
However, long-term results of retrospective studies suggest that, for the great majority of individuals, mastectomy or conservative surgery with radiation therapy were be equally effective. The results at 5 and 10 years from prospective randomized trials indicate that survival following primary radiation therapy for early breast cancer is equivalent to that following mastectomy. When competently performed, primary radiation therapy gives...
Radiation Therapy of a Chordoma of the Thoracic Vertebra: a Case Report and Review of Literatures
Joo Young Kim, Myung Sun Choi
Radiat Oncol J. 1988;6(2):295-300.
Chordom is a malignant tumor arising from the primitive notochord involving the axial skeleton. It usually occurs at sacrococcygeal and basisphenoidal area but only rarely does at other vertebral areas, especially at the thoracic vertebrae. It has a slow growth rate and is locally aggressive with an extremely high rate of local recurrence. Either surgery or radiation alone often fails to...
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